Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Lowest round trip fares by airline from San Francisco and Buffalo

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Cheap flights from San Francisco to Buffalo

Cheap flights from San Francisco to Buffalo

Are you ready to book your flight, but feeling nervous about paying too much if the price drops? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus a $50 CheapCash bonus, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a Buffalo Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Buffalo vacation that you can't get when you book flights and hotel separately.

Relax in Buffalo With Confidence and Convenience

Going cheap doesn't mean giving up great service. Our agents are available 24/7 to help you find the right cheap flights and hotel, and to answer questions about your trip.

Need to grab a cheap travel deal while you're on the go? Download our mobile app, where you can search and book just like you would on your home computer. Stay in-the-know on great rates on flights from San Francisco to Buffalo by signing up for exclusive email deals.

Hotels in Buffalo

See all 180 Properties in Buffalo
Millennium Buffalo

Millennium Buffalo

2040 Walden Ave, Buffalo, NY
    3.5 out of 5.0
     
     
    3.8 out of 5 (11 reviews)

    This family-friendly Buffalo hotel is located near the airport, within 1 mi (2 km) of Holiday Twin Rinks and Walden Galleria Mall. Wilcox Mansion - Theodore ...

    Millennium Buffalo$76

    Millennium Buffalo$76
    Buffalo Grand Hotel

    Buffalo Grand Hotel

    120 Church St, Buffalo, NY
      3.0 out of 5.0
       
       
      3.4 out of 5 (41 reviews)

      Located in Downtown Buffalo, this hotel is within a 10-minute walk of Guaranty / Prudential Building, Coca-Cola Field, and Canalside. Buffalo and Erie County ...

      Buffalo Grand Hotel$79

      Buffalo Grand Hotel$79
      Hotel Buffalo International Airport

      Hotel Buffalo International Airport

      901 Dick Rd, Buffalo, NY
        2.5 out of 5.0
         
         
        3.8 out of 5 (4 reviews)

        Situated in Buffalo, this hotel is within 3 mi (5 km) of Walden Galleria Mall, Island Park, and Holiday Twin Rinks. Glen Falls is 2.9 mi (4.6 km) away.

        Hotel Buffalo International Airport$62

        Hotel Buffalo International Airport$62
        Days Hotel by Wyndham Buffalo Airport

        Days Hotel by Wyndham Buffalo Airport

        4345 Genesee St, Buffalo, NY
          3.0 out of 5.0
           
           
          3.2 out of 5 (17 reviews)

          Situated near the airport, this hotel is within 6 mi (10 km) of Island Park, Walden Galleria Mall, and Glen Falls. Holiday Twin Rinks and Eastern Hills Mall ...

          Days Hotel by Wyndham Buffalo Airport$69

          Days Hotel by Wyndham Buffalo Airport$69
          Hyatt Regency Buffalo / Hotel and Conference Center

          Hyatt Regency Buffalo / Hotel and Conference Center

          Two Fountain Plaza, Buffalo, NY
            3.5 out of 5.0
             
             
            3.9 out of 5 (23 reviews)

            Located in Downtown Buffalo, this spa hotel is within a 15-minute walk of Shea's Performing Arts Center and Coca-Cola Field. Buffalo and Erie County Naval and ...

            Hyatt Regency Buffalo / Hotel and Conference Center$113

            Hyatt Regency Buffalo / Hotel and Conference Center$113
            Country Inn & Suites by Radisson, Buffalo South I-90, NY

            Country Inn & Suites by Radisson, Buffalo South I-90, NY

            164b Slade Ave, West Seneca, NY
              2.5 out of 5.0
               
               
              4.2 out of 5 (5 reviews)

              Situated in West Seneca, this hotel is 2.6 mi (4.1 km) from Buffalo and Erie County Botanical Gardens and within 6 mi (10 km) of Pierce - Arrow Museum and New ...

              Country Inn & Suites by Radisson, Buffalo South I-90, NY$60

              Country Inn & Suites by Radisson, Buffalo South I-90, NY$60
              Hyatt Place Buffalo/Amherst

              Hyatt Place Buffalo/Amherst

              5020 Main Street, Amherst, NY
                3.0 out of 5.0
                 
                 
                4.0 out of 5 (5 reviews)

                Situated near the airport, this hotel is within 2 mi (3 km) of Daemen College, Island Park, and Glen Falls. Grover Cleveland Golf Course and University at Buffalo ...

                Hyatt Place Buffalo/Amherst$105

                Hyatt Place Buffalo/Amherst$105
                Wyndham Garden Buffalo Downtown

                Wyndham Garden Buffalo Downtown

                125 High St, Buffalo, NY
                  3.0 out of 5.0
                   
                   
                  4.2 out of 5 (4 reviews)

                  Located in Downtown Buffalo, this hotel is within 1 mi (2 km) of Buffalo Niagara Medical Campus and Shea's Performing Arts Center. Buffalo Niagara Convention ...

                  Wyndham Garden Buffalo Downtown$87

                  Wyndham Garden Buffalo Downtown$87
                  Embassy Suites Buffalo

                  Embassy Suites Buffalo

                  200 Delaware Avenue, Buffalo, NY
                    3.5 out of 5.0
                     
                     
                    4.0 out of 5 (5 reviews)

                    Located in Downtown Buffalo, this hotel is within a 5-minute walk of Statler Tower and Buffalo Niagara Convention Center. Coca-Cola Field and Wilcox Mansion ...

                    Embassy Suites Buffalo$122

                    Embassy Suites Buffalo$122
                    Motel 6 Buffalo Airport

                    Motel 6 Buffalo Airport

                    52 Freeman Rd, Williamsville, NY
                      2.0 out of 5.0
                       
                       
                      3.2 out of 5 (5 reviews)

                      Situated in Williamsville, this motel is within 3 mi (5 km) of Eastern Hills Mall, Samuel’s Grande Manor, and Diamond Hawk Golf Course. Island Park and Glen ...

                      Motel 6 Buffalo Airport$34

                      Motel 6 Buffalo Airport$34
                      Map

                      *Savings based on all holiday package bookings with Flight + Hotel on CheapTickets.com from January through December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

                      *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.