Important: This destination may have COVID-19 travel restrictions in place, including specific restrictions for lodging. Check any national, local, and health advisories for this destination before you book.

Cheap flights from Detroit (DTT) to Key West (EYW)

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Lowest round trip fares by airline from Detroit and Key West

Cheapest prices ($157 One Way, $265 Round Trip) found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Sun, May 16
DTW
Detroit
EYW
Key West
$157
American Airlines
Wed, May 26
DTW
Detroit
EYW
Key West
$169
American Airlines
Sat, May 29
DTW
Detroit
EYW
Key West
$188
United
Fri, May 21
DTW
Detroit
EYW
Key West
$189
American Airlines
Fri, May 14
FNT
Flint
EYW
Key West
$195
American Airlines
Wed, May 19 - Wed, May 26
DTW
Detroit
EYW
Key West
$265
American Airlines
Wed, May 19 - Tue, May 25
DTW
Detroit
EYW
Key West
$295
American Airlines
Thu, May 20 - Wed, May 26
DTW
Detroit
EYW
Key West
$297
Delta
Sun, May 16 - Thu, May 20
DTW
Detroit
EYW
Key West
$302
American Airlines
Tue, May 18 - Wed, May 26
DTW
Detroit
EYW
Key West
$310
American Airlines

Great Deals On Cheap Hotels in Key West

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street, Key West, FL
The price is $288 per night from May 10 to May 10
Located in Key West Historic District, this hotel is steps from Simonton Beach, Duval Street, and South Beach. Higgs Beach and Southernmost Point are also within ...
4.3/5Excellent! (4 reviews)
"So close to beach and restaurants in walking distance"

Reviewed on Mar 14, 2021

Southwinds Motel
Seashell Motel & Key West Hostel

Seashell Motel & Key West Hostel

1.5 out of 5
718 South Street, Key West, FL
The price is $129 per night from Jun 1 to Jun 1
Located in Old Town Key West, this hostel is within a 5-minute walk of Duval Street and South Beach. Higgs Beach and Key West Butterfly and Nature Conservatory ...
3.5/5Good! (4 reviews)
"First off for the money we paid the property was in poor condition you can see through the door there were cracks all around the bottom of it then when we flush the toilet twice sewage came back up into the shower stall the beds were up against the wall so you had to climb out at night to go to the ..."

Reviewed on Mar 19, 2020

Seashell Motel & Key West Hostel
Duval House

Duval House

3 out of 5
815 Duval St, Key West, FL
The price is $258 per night from May 31 to May 31
Located in Key West Historic District, this bed & breakfast is steps from Duval Street and Ernest Hemingway Home and Museum. South Beach and Key West Butterfly ...
5/5Exceptional! (2 reviews)
"Great location and charm. Attentive staff. Good breakfast"

Reviewed on Sep 16, 2019

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fly From Detroit to Key West

Origin Detroit
Destination Key West
Number of Daily Flights
Earliest Flight Departure Date
Latest Flight Departure Date
Popular Airlines

Cheap flights from Detroit to Key West

Are you ready to book your flight, but feeling nervous about paying too much if prices drop in a few days? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus $50 more in CheapCash, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a Key West Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Key West vacation that you can't get when you book flights and hotel separately.

Relax in Key West With Confidence and Convenience

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.