Compare Cheap Hotels in Southeast Missouri

When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River.

A stay at Drury Inn & Suites Sikeston, MO places you in the heart of Sikeston, a 1-minute drive from City of Miner Convention Center and 5 minutes from Sikeston Depot Museum.

Located in Farmington, Baymont Inn and Suites by Wyndham Farmington, MO is in the historical district, within a 15-minute drive of Crown Pointe Golf Club and St. Joe State Park.

When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Shawnee National Forest.

Located in Sikeston, Days Inn and Suites by Wyndham Sikeston is a 3-minute drive from City of Miner Convention Center and 7 minutes from Sikeston Depot Museum.

With a stay at Candlewood Suites Cape Girardeau by IHG in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River.

A stay at Drury Inn & Suites Hayti Caruthersville places you in the heart of Hayti, within a 5-minute drive of Hayti Pentecostal Holiness Church and Hayti Park.

Located in Festus, La Quinta Inn & Suites by Wyndham Festus - St. Louis South is in a rural location, within a 5-minute drive of Jorkerst Memorial Park and Festus Public Library.

With a stay at Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy in French Village, you'll be in a regional park, and 10.6 mi (17.1 km) from Weingarten Vineyard and 14.4 mi (23.2 km) from Big River.

With a stay at Lake Wappapello in Williamsville, you'll be within a 15-minute drive of Poplar Bluff Regional Medical Center and North Main Street Historic District.

Located in Poplar Bluff, Hampton Inn Poplar Bluff is in a rural location, within a 5-minute drive of Poplar Bluff Regional Medical Center and North Main Street Historic District.

With a stay at Motel 6 Poplar Bluff, MO in Poplar Bluff, you'll be within a 10-minute drive of Mark Twain National Forest and Poplar Bluff Regional Medical Center.