Compare Hotels with Pools in Cape Girardeau
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Featured Cape Girardeau Hotels with Pools
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
$95 nightly
The price is $107 total per night
$107 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
With a stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Breakfast included
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St Cape Girardeau MO
$70 nightly
The price is $79 total per night
$79 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Pear Tree Inn Cape Girardeau Near the Medical Center, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pet friendly
Free WiFi
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night
$102 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Hot Tub
Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
$70 nightly
The price is $84 total per night
$84 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
With a stay at Candlewood Suites Cape Girardeau by IHG in Cape Girardeau, you'll be within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Pet friendly
Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd Cape Girardeau MO
$99 nightly
The price is $112 total per night
$112 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hampton Inn Cape Girardeau I 55 East in Cape Girardeau, you'll be within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Breakfast included
Quality Inn
2011 North Kingshighway Cape Girardeau MO
$60 nightly
The price is $67 total per night
$67 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Quality Inn in Cape Girardeau, you'll be within a 10-minute drive of Mississippi River and Saint Francis Healthcare System.
Pool
Breakfast included
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night
$102 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Cape Girardeau hotels essential information
Accommodation | 173 hotels |
|---|---|
Lowest Price | $67 |
Highest Price | $112 |
Popular hotels | Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Pear Tree Inn Cape Girardeau Near the Medical Center, Drury Inn & Suites Cape Girardeau, Candlewood Suites Cape Girardeau by IHG, Hampton Inn Cape Girardeau I 55 East, Quality Inn, Drury Plaza Hotel Cape Girardeau Conference Center |
Most Recent Cape Girardeau Hotel Reviews
Drury Inn & Suites Cape Girardeau
5 out of 5
Posted 23 hours ago
CheapTickets Verified Review
"Yes"
A verified traveler stayed at Drury Inn & Suites Cape Girardeau
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