Compare Cheap 4 Star Hotels

When you stay at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau in Jackson, you'll be in the business district, within a 15-minute drive of Shawnee National Forest and Mississippi River.

With a stay at Drury Inn & Suites Jackson MO, you'll be centrally located in Jackson, within a 10-minute drive of Cape Girardeau Conservation Nature Center and Saint Francis Healthcare System.

With a stay at Comfort Suites Jackson-Cape Girardeau, you'll be centrally located in Jackson, within a 15-minute drive of Shawnee National Forest and Mississippi River.

When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River.

When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Shawnee National Forest.

Located in Murphysboro, Holiday Inn Express & Suites Murphysboro - Carbondale by IHG is within a 15-minute drive of Shawnee National Forest and Southern Illinois University.

Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, a 3-minute drive from Saint Francis Medical Center and 5 minutes from Saint Francis Healthcare System.

When you stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Shawnee National Forest and Mississippi River.

With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River.

With a stay at Candlewood Suites Cape Girardeau by IHG in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River.

With a stay at Fairfield Inn & Suites by Marriott Cape Girardeau in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River.

With a stay at Quality Inn Cape Girardeau North in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River.