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Featured Cape Girardeau Cheap Hotels

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
$70 nightly
The price is $79 total per night
$79 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, within a 5-minute drive of Saint Francis Medical Center and Saint Francis Healthcare System.
Breakfast included
Pet friendly
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street Cape Girardeau MO
$95 nightly
The price is $107 total per night
$107 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
With a stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Breakfast included
Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway Cape Girardeau MO
$60 nightly
The price is $67 total per night
$67 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Quality Inn Cape Girardeau North in Cape Girardeau, you'll be within a 10-minute drive of Mississippi River and Saint Francis Healthcare System.
Pool
Breakfast included
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St Cape Girardeau MO
$70 nightly
The price is $79 total per night
$79 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Pear Tree Inn Cape Girardeau Near the Medical Center, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pet friendly
Free WiFi
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Cape Girardeau hotels essential information

Accommodation
173 hotels
Lowest Price
$67
Highest Price
$107
Popular hotels
Pear Tree Inn Cape Girardeau West, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Quality Inn, Pear Tree Inn Cape Girardeau Near the Medical Center

Most Recent Cape Girardeau Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

5 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Yes"
A verified traveler stayed at Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau

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