Compare Business Hotels in Seneca
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Featured Seneca Business Hotels

Best Western Seneca-Clemson
511 Bypass Highway 123 Seneca SC
$94 nightly
The price is $103 total per night
$103 total
May 13 - May 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Best Western Seneca-Clemson in Seneca, you'll be a 1-minute drive from Lake Keowee and 8 minutes from Clemson University.
Pool
Breakfast included

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street Seneca SC
$111 nightly
The price is $122 total per night
$122 total
May 24 - May 25
Total with taxes and fees
When you stay at Hampton Inn & Suites Seneca-Clemson Area in Seneca, you'll be in the business district, a 2-minute drive from Lake Keowee and 7 minutes from Clemson University.
Pool
Breakfast included

Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd Seneca SC
$76 nightly
The price is $83 total per night
$83 total
May 17 - May 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Days Inn by Wyndham Seneca / Clemson Area in Seneca, you'll be in the business district, within a 15-minute drive of Lake Keowee and Clemson University.
Pool
Breakfast included

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
$91 nightly
The price is $99 total per night
$99 total
May 17 - May 18
Total with taxes and fees
Free Cancellation
With a stay at Quality Inn Seneca Clemson Area US-123, you'll be centrally located in Seneca, a 3-minute drive from Lake Keowee and 10 minutes from Clemson University.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Seneca hotels essential information
Accommodation | 1,656 hotels |
|---|---|
Lowest Price | $83 |
Highest Price | $122 |
Popular hotels | Best Western Seneca-Clemson, Hampton Inn & Suites Seneca-Clemson Area, Days Inn by Wyndham Seneca / Clemson Area, Quality Inn Seneca Clemson Area US-123 |
Most Recent Seneca Hotel Reviews

Fairfield Inn & Suites Seneca Clemson Univ Area
4 out of 5
Posted 5 hours ago
CheapTickets Verified Review
"Yes and yes,the room was clean but it had a bad smell, the handicap railing in bathroom at toilet was loose feeling. The lady at front desk when we arrived was rude
"
A verified traveler stayed at Fairfield Inn & Suites Seneca Clemson Univ Area
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