Compare Hotels with Air Conditioning in Seneca

Secret Bargains - Save an extra 10% or more on select Hotels with Air Conditioning

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Featured Seneca Hotels with Air Conditioning

Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123 Seneca SC
$94 nightly
The price is $103 total per night
$103 total
May 13 - May 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Best Western Seneca-Clemson in Seneca, you'll be a 1-minute drive from Lake Keowee and 8 minutes from Clemson University.
Pool
Breakfast included
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Seneca SC
With a stay at this cabin in Seneca, you'll be in the mountains, within a 15-minute drive of Lake Keowee and Golden Corner Plaza.
Kitchen
Washer
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd Seneca SC
$76 nightly
The price is $83 total per night
$83 total
May 17 - May 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Days Inn by Wyndham Seneca / Clemson Area in Seneca, you'll be in the business district, within a 15-minute drive of Lake Keowee and Clemson University.
Pool
Breakfast included
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
$114 nightly
The price is $125 total per night
$125 total
May 10 - May 11
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Hampton Inn & Suites Seneca-Clemson Area in Seneca, you'll be in the business district, a 2-minute drive from Lake Keowee and 7 minutes from Clemson University.
Pool
Breakfast included
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

Seneca SC
Located in Seneca, this vacation home is on the waterfront, within a 15-minute drive of Lake Hartwell and Friendship Recreaction Area.
Pool
Kitchen
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
$88 nightly
The price is $97 total per night
$97 total
May 24 - May 25
Total with taxes and fees
Free Cancellation
With a stay at Quality Inn Seneca Clemson Area US-123, you'll be centrally located in Seneca, a 3-minute drive from Lake Keowee and 10 minutes from Clemson University.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Seneca
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Seneca hotels essential information

Accommodation
1,655 hotels
Lowest Price
$83
Highest Price
$125
Popular hotels
Best Western Seneca-Clemson, Fall fun at the cabin! Convenient to Lake Keowee and Clemson, Days Inn by Wyndham Seneca / Clemson Area, Hampton Inn & Suites Seneca-Clemson Area, 😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks, Quality Inn Seneca Clemson Area US-123

Most Recent Seneca Hotel Reviews

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

4 out of 5
Posted 18 hours ago
CheapTickets Verified Review
"The TV feed was intermittent. The bathroom floor tile was loose as the shower door was designed to leak on the floor. (poor design) The property is clean and people friendly and hospitable."
A verified traveler stayed at Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area

Top Picks