Compare Boutique Hotels in Panama

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Featured Panama Boutique Hotels

De Ville Hotel

De Ville Hotel

4.5 out of 5
50 street and Beatriz M. De Cabal Panama City
A stay at De Ville Hotel places you in the heart of Panama City, within a 15-minute walk of Via Espana and Avenida Balboa.
Breakfast included
Parking included
Gatto Blanco Party Hotel

Gatto Blanco Party Hotel

3.5 out of 5
Avenida B con Calle 8 Panama City Panama
A stay at Gatto Blanco Party Hotel places you in the heart of Panama City, within a 15-minute walk of Avenida Balboa and Cinta Costera.
Free WiFi
Restaurant
Los Establos Boutique Resort- All Inclusive

Los Establos Boutique Resort- All Inclusive

4.5 out of 5
Jaramillo Arriba Jaramillo Chiriqui
$547 nightly
The price is $599 total per night
$599 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
When you stay at Los Establos Boutique Resort- All Inclusive in Jaramillo, you'll be in a regional park, within a 5-minute drive of El Explorador and Church of San Juan Bautista.
Pool
All inclusive
Playa Tortuga Hotel Beach And Resort

Playa Tortuga Hotel Beach And Resort

4 out of 5
Camino A Playa Bluff Y P Creek Bocas del Toro Bocas del Toro
With a stay at Playa Tortuga Hotel Beach And Resort in Bocas del Toro, you'll be on the beach, a 4-minute walk from Tortuga Beach and a 1-minute drive from Paunch Beach.
Pool
Parking included
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5 out of 5
Avenida Aquilino de La Guardia Panama City Panama
$220 nightly
The price is $242 total per night
$242 total
Dec 20 - Dec 21
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Bristol Panama, a Registry Collection Hotel, you'll be centrally located in Panama City, steps from Calle 50 and within a 10-minute walk of Soho City Center.
Pool
Spa
Hotel Casa Panamá

Hotel Casa Panamá

4 out of 5
Avenida Eloy Alfaro y Calle 11 Panama City
$73 nightly
The price is $80 total per night
$80 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Panama City (Casco Viejo), Hotel Casa Panamá is within a 10-minute walk of Avenida Balboa and Cinta Costera.
Pet friendly
Free WiFi
The Haven and Spa - Health and Wellness Accommodation - Adults Only

The Haven and Spa - Health and Wellness Accommodation - Adults Only

3.5 out of 5
Avenida A Oeste, Bajo Boquete Chiriqui
When you stay at The Haven and Spa - Health and Wellness Accommodation - Adults Only in Boquete, you'll be in a national park, within a 5-minute drive of Boquete Library and Municipal Park.
Pool
Hot Tub
The Saba Hotel

The Saba Hotel

3.5 out of 5
Panama Internacional zone,Argentina Ave Panama City Panama
With a stay at The Saba Hotel, you'll be centrally located in Panama City, within a 5-minute drive of Albrook Shopping Mall and Via Espana.
Parking included
Free WiFi
The Riverside Inn

The Riverside Inn

3.5 out of 5
11 de Abril Los Naranjos Chiriqui
$234 nightly
The price is $257 total per night
$257 total
Dec 14 - Dec 15
Total with taxes and fees
With a stay at The Riverside Inn in Los Naranjos, you'll be within a 5-minute drive of Municipal Park and Boquete Community Players Theater and Events Center.
Pet friendly
Parking included
Exe Oriental Panama

Exe Oriental Panama

4 out of 5
Avenida 2da Sur, Obarrio, Bella Vista Panama City Panama
$72 nightly
The price is $79 total per night
$79 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Exe Oriental Panama in Panama City (Bella Vista), you'll be a 3-minute walk from Via Espana and 14 minutes by foot from Avenida Balboa.
Free WiFi
Restaurant
American Trade Hotel

American Trade Hotel

4.5 out of 5
Plaza Herrera Casco Viejo Panama City Panama
$262 nightly
The price is $289 total per night
$289 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
American Trade Hotel is in the heart of Panama City, within a 5-minute walk of Museum of History Panama and Independence Square.
Pool
Pet friendly
Toscana Inn

Toscana Inn

3.5 out of 5
Via España, Calle D El Cangrejo Panama City Panama (province)
Free Cancellation
Reserve now, pay when you stay
With a stay at Toscana Inn, you'll be centrally located in Panama City, within a 5-minute drive of Via Espana and Avenida Balboa.
Pet friendly
Free WiFi
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panama Boutique Hotels essential information

 

Boutique Hotels in Panama

21

Highest price
$599
Cheapest price
$79
Total number of hotels in Panama
3,584
Popular hotels
De Ville Hotel, Gatto Blanco Party Hotel, Los Establos Boutique Resort- All Inclusive, Playa Tortuga Hotel Beach And Resort, Bristol Panama, a Registry Collection Hotel, Hotel Casa Panamá, The Haven and Spa - Health and Wellness Accommodation - Adults Only, The Saba Hotel, The Riverside Inn, Exe Oriental Panama, American Trade Hotel, Toscana Inn

 

Most Recent Panama Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Posted 3 days ago
CheapTickets Verified Review
"The Staff was Amazing. Pamela at the hotels store mad my fiancé and I feel like family. The rooms are spacious and clean. "
A verified traveler stayed at Hotel Riu Plaza Panama
Hotel Riu Plaza Panama

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