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Independent in Charleston
Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
$62 nightly
The price is $69 total per night
$69 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.46 mi from city center
With a stay at Super 8 by Wyndham Charleston/Sikeston East MO, you'll be centrally located in Charleston, 10.3 mi (16.6 km) from Mississippi River and 12.7 mi (20.4 km) from Fort Defiance State Park.
Quality Inn Charleston - Sikeston
102 Drake St Charleston MO
$66 nightly
The price is $73 total per night
$73 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.03 mi from city center
When you stay at Quality Inn Charleston - Sikeston in Charleston, you'll be 13 minutes by car from City of Miner Convention Center.
Eagle Inn Charleston
2811 East Marshall Street Charleston MO
$60 nightly
The price is $67 total per night
$67 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
2.32 mi from city center
With a stay at Eagle Inn Charleston in Charleston, you'll be 10.1 mi (16.3 km) from Mississippi River and 11.7 mi (18.9 km) from Fort Defiance State Park.
Pet friendly
Parking included
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night
$102 total
Dec 18 - Dec 19
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
29.3 mi from city center
With a stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
The Riverview
777 Main St Cape Girardeau MO
$96 nightly
The price is $109 total per night
$109 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
28.46 mi from city center
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Isle Casino Cape Girardeau.
Parking included
Free WiFi
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
$95 nightly
The price is $108 total per night
$108 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
13.51 mi from city center
When you stay at Hampton Inn Sikeston in Sikeston, you'll be near the airport, within a 5-minute drive of Central Park and Sikeston Depot Museum.
Courtyard by Marriott Cape Girardeau Downtown
400 Broadway St. Cape Girardeau MO
$116 nightly
The price is $131 total per night
$131 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
28.12 mi from city center
Located in Cape Girardeau, Courtyard by Marriott Cape Girardeau Downtown is within a 15-minute walk of Shawnee National Forest and eDen Spa & Salon.
Parking included
Free WiFi
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$90 nightly
The price is $103 total per night
$103 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.49 mi from city center
A stay at Drury Inn & Suites Sikeston, MO places you in the heart of Sikeston, a 1-minute drive from City of Miner Convention Center and 5 minutes from Sikeston Depot Museum.
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St Cape Girardeau MO
$70 nightly
The price is $79 total per night
$79 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
29 mi from city center
With a stay at Pear Tree Inn Cape Girardeau Near the Medical Center, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
$95 nightly
The price is $107 total per night
$107 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
28.92 mi from city center
With a stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$70 nightly
The price is $79 total per night
$79 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
29.1 mi from city center
Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, within a 5-minute drive of Saint Francis Medical Center and Saint Francis Healthcare System.
Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
$70 nightly
The price is $84 total per night
$84 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
28.07 mi from city center
With a stay at Candlewood Suites Cape Girardeau by IHG in Cape Girardeau, you'll be within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Charleston hotels essential information
Accommodation | 93 hotels |
|---|---|
Lowest Price | $67 |
Highest Price | $131 |
Popular hotels | Super 8 by Wyndham Charleston/Sikeston East MO, Quality Inn Charleston - Sikeston, Eagle Inn Charleston, Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview, Hampton Inn Sikeston, Courtyard by Marriott Cape Girardeau Downtown, Drury Inn & Suites Sikeston, MO, Pear Tree Inn Cape Girardeau Near the Medical Center, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Pear Tree Inn Cape Girardeau West, Candlewood Suites Cape Girardeau by IHG |
Most Recent Charleston Hotel Reviews
Hampton Inn Sikeston
5 out of 5
Posted 3 days ago
CheapTickets Verified Review
"Yes"
A verified traveler stayed at Hampton Inn Sikeston
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