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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property

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Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, a desk, a chair, a kitchenette, and a bathroom.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A buffet with labeled containers of omelets and other dishes.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Free WiFi
  • Air conditioning
The current price is $116
$103 nightly
$116 total
Total with taxes and fees
Sep 6 - Sep 7

Explore the area

View in a map
3253 William Street, Cape Girardeau, MO, 63701
  • Place, Cape Splash Family Aquatic Center
    ‪4 min drive‬
  • Place, Southeast Missouri State University
    ‪7 min drive‬
  • Place, Century Casino & Hotel Cape Girardeau
    ‪9 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪5 min drive‬

Room options

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

A hotel room with two beds, a TV, a desk, and a chair.

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(6 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

A bed with white bedding and pillows against a wooden headboard.

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.6 out of 10
Exceptional
(7 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed

A hotel room with a bed, a blue sofa, a desk, and a green chair.

Suite, 1 King Bed

9.8 out of 10
Exceptional
(37 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 2 Queen Beds

A bed with white bedding and pillows against a wooden headboard.

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(68 reviews)
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

A hotel room with two beds, a desk, a chair, a sofa, and a lamp.

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(17 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 1 Queen Bed

A bed with white bedding and pillows against a wooden headboard.

Standard Room, 1 Queen Bed

9.4 out of 10
Exceptional
(6 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed
  • Free WiFi

View all photos for Standard Room

A bed with white bedding and pillows against a wooden headboard.

Standard Room

8.4 out of 10
Very good
(5 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Feature)

A bed with white bedding and pillows against a wooden headboard.

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible (Mobility)

A bed with white bedding and pillows against a wooden headboard.

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

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4.8 out of 5, Exceptional, 1,012 reviews
$100 nightly
The price is $113
Aug 13 - Aug 14
Total with taxes and fees
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About the neighborhood

Cape Girardeau

When you stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Shawnee National Forest and Mississippi River. .This spa hotel is 0.5 mi (0.8 km) from Saint Francis Medical Center and 2.4 mi (3.8 km) from Cape Splash Family Aquatic Center.

What's nearby

  • Cape Splash Family Aquatic Center - 4 min drive - 2.9 miles
  • Riverfront Park - 7 min drive - 5.5 miles
  • Southeast Missouri State University - 7 min drive - 3.7 miles
  • Century Casino & Hotel Cape Girardeau - 9 min drive - 6.5 miles
  • Giant City State Park - 54 min drive - 49.1 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬7 min walk
  • ‪Rhodes - ‬20 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪Qdoba Mexican Eats - ‬13 min walk
  • ‪Taco Bell - ‬12 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers 102 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas. Pillowtop beds feature down comforters and premium bedding. A pillow menu is available. 52-inch flat-screen televisions come with premium cable channels. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool and a fitness center.
Guests can indulge in a pampering treatment at the hotel's full-service spa.
Make yourself at home in one of the 102 guestrooms featuring microwaves and flat-screen televisions. Your pillowtop bed comes with down comforters and premium bedding. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms have complimentary toiletries and hair dryers.
Take time to pamper yourself with a visit to the full-service spa. If you're looking for recreational opportunities, you'll find an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access, a banquet hall, and a vending machine.
A complimentary breakfast is included.
Featured amenities include complimentary wired internet access, a business center, and complimentary newspapers in the lobby. Planning an event in Cape Girardeau? This hotel has 118 square feet (11 square meters) of space consisting of conference space and a meeting room. Free self parking is available onsite.
A complimentary breakfast is offered.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business center
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoking not allowed

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed

Children and extra beds

Children are welcome
Cribs (infant beds) are not available

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a fire extinguisher and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 11 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 777 out of 1006 reviews
Rating 8 - Good. 149 out of 1006 reviews
Rating 6 - Okay. 41 out of 1006 reviews
Rating 4 - Poor. 19 out of 1006 reviews
Rating 2 - Terrible. 20 out of 1006 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified review

10/10 Excellent

Jeffrey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
clean room, easy parking, solid breakfast
Stayed 1 night in Apr 2026
Verified review

8/10 Good

Leneatha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent stay.....only thing missing was a hot tub by the pool, everything else was A+
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

Sarah

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, large rooms, comfortable beds, friendly staff, huge breakfast room and nice breakfast selection. Would absolutely stay here again!
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Sarah

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, large rooms, comfortable beds, friendly staff, huge breakfast room and nice breakfast selection. Would absolutely stay here again!
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Linda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was very clean. Breakfast was good with several options. Would recommend staying here.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel is in a convenient central area. Was clean and staff was friendly.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Heather

Liked: Cleanliness, staff & service, amenities
Room was clean, breakfast was nice.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Jeff

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was clean and the room are comfortable. It is located right off the interstate near a lot of restaurants, shopping and large medical facility.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Amber

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was probably the cleanest hotel we have ever stayed in. The beds were also very comfortable. Staff was also friendly and helpful.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Bryan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent place to stay.
Stayed 1 night in Nov 2025
Verified review

10/10 Excellent

RYAN

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great Staff!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Sara

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
For the price, this stay exceeded my expectations. Everything was clean and the staff were very helpful. The suite we stayed in had many helpful features. Breakfast also was delicious and there were many options.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Vanessa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was recommended by a friend of ours. The hotel staff were great. It was clean and quiet. Me and my husband enjoyed our stay.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Arriel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room staff is very nice parking it great
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Rex

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was very good and staff was extremely friendly and rooms were very clean
Stayed 2 nights in Jan 2026
Verified review

10/10 Excellent

Matthew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel and room was extremely clean. The lobby and breakfast area was clean, well organized and inviting. There was plenty of parking. The breakfast was superior compared to most I've experienced and was really well laid out and organized and staff maintained supply of food superbly
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

John

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was excellent. Staff was very friendly and helpful.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Janelle

lovely hotel
Stayed 2 nights in Dec 2025
Verified review

10/10 Excellent

Andrew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I was amazed to find out this place is 20+ years old. It is in great shape. Room was wonderful. Breakfast was great; very lovely stay.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Nancy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was very clean. Very quiet even though the hotel was full. Breakfast was wonderful.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Nellie

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and staff was very friendly.
Stayed 2 nights in Nov 2025
Verified review

10/10 Excellent

Mike

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place to stay.
Stayed 1 night in Jun 2025
Verified review

8/10 Good

Mary

Liked: Cleanliness, staff & service, amenities
Clean, courteous staff
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Summer

Liked: Cleanliness, staff & service, amenities
It was amazing check in to check out
Stayed 1 night in Aug 2025
Verified review

10/10 Excellent

Marcus

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful room, whirlpool bath, breakfast, staff
Stayed 1 night in Nov 2025