See all 172 hotels in Cape Girardeau
- Tru By Hilton Cape Girardeau
- Beautifully Renovated Farmhouse in Jackson, MO
- Charming 1-bedroom B&B with AC, WiFi in historic Cape Girardeau
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Eagles Crossing is a Newly Renovated 3-Bed Farmhouse with a Large Deck & Hot Tub
- Charming farmhouse on a beautiful horse ranch-Shawnee Hills Wine Trail
- Beautiful Cabin Retreat