St. James Vacation Rentals

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Vacation Rentals in St. James

The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

Saint James MO

$197 nightly

$200 total

Dec 7 - Dec 8

Total with taxes and fees

Located in St. James, this vacation home is within a 10-minute drive of Rosati Winery Museum and Heinrichshaus Vineyard And Winery.

Kitchen

Washer

The James Stay on Historic Route 66, minutes away from Wineries & Restaurants

Saint James MO

$176 nightly

$176 total

Dec 8 - Dec 9

Total with taxes and fees

With a stay at this vacation home in St. James, you'll be within a 5-minute drive of Meramec Vineyards and St. James Winery.

Kitchen

Washer

Peaceful relaxing and fun

Salem MO

When you stay at this vacation home in Salem, you'll be on a lake and 15 minutes by car from Salem memorial hospital.

Kitchen

Pet friendly

Townside Blue House

Saint James MO

$169 nightly

$176 total

Dec 6 - Dec 7

Total with taxes and fees

Located in St. James, this vacation home is within a 5-minute drive of Meramec Vineyards and St. James Winery.

Kitchen

Washer

Luxury Home in Woods w/ Easy Access to Large Private Gravel Bar on Meramec River

Steelville MO

Located in Steelville, this vacation home is on the waterfront, within a 15-minute drive of Meramec River and Mark Twain National Forest.

Kitchen

Washer

Cozy Modern Farmhouse that Sleeps 8

Rolla MO

Located in Rolla, this vacation home is within a 5-minute drive of Ponzer Park and Cedar Street Playhouse.

Kitchen

Washer

Vineyard Ridge Farmhouse

Saint James MO

$256 nightly

$256 total

Jan 5 - Jan 6, 2026

Total with taxes and fees

When you stay at this vacation home in St. James, you'll be within a 10-minute drive of Rosati Winery Museum and Heinrichshaus Vineyard And Winery.

Kitchen

Washer

4 bedrooms Sleeps 14

Salem MO

$248 nightly

$248 total

Dec 6 - Dec 7

Total with taxes and fees

Located in Salem, this vacation home is within a 15-minute drive of Salem memorial hospital and Mark Twain National Forest.

Washer

Dryer

Charming house near Maramec Spring Park, Steelville/St. James

Steelville MO

Located in Steelville, this vacation home is a 1-minute drive from Woodson K. Woods Memorial Conservation Area and 6 minutes from Maramec Spring Park.

Kitchen

Washer

2BR | Pet-Friendly | Fenced Yard | Near Wineries

Saint James MO

$223 nightly

$235 total

Dec 31 - Jan 1, 2026

Total with taxes and fees

With a stay at this vacation home in St. James, you'll be within a 5-minute drive of St. James Winery and Meramec Vineyards.

Kitchen

Washer

The Rock House - 1 bdrm, 1 bath Salem Missouri Vacation Rental

Salem MO

When you stay at this vacation home in Salem, you'll be 5 minutes by car from Salem memorial hospital.

Kitchen

Free WiFi

Located In The Foothills Of The Ozarks, Enjoy A Peaceful Setting At The Lodge.

Cherryville MO

When you stay at this vacation home in Cherryville, you'll be steps from Mark Twain National Forest.

Kitchen

Dryer

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.