Seneca Vacation Rentals

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Check dates for Seneca hotels

Vacation Rentals in Seneca

Lake Jocassee ~ Easy Lake Access ~ Loved By Our Guests ~ Pet Friendly

Salem SC

With a stay at this vacation home in Salem, you'll be on a lake, within a 10-minute drive of Lake Keowee and Lake Jocassee.

Kitchen

Washer

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more

Six Mile SC

$703 nightly

$780 total

Oct 4 - Oct 5

Total with taxes and fees

With a stay at this vacation home in Six Mile, you'll be on the waterfront, within a 15-minute drive of Lake Keowee and World of Energy.

Kitchen

Washer

"Cabin in the Cove" Private waterfront home on beautiful Lake Hartwell

Martin GA

When you stay at this vacation home in Martin, you'll be on the waterfront and steps from Lake Hartwell.

Kitchen

Washer

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water

Seneca SC

When you stay at this vacation home in Seneca, you'll be on the waterfront, within a 15-minute drive of Memorial Stadium and Lake Keowee.

Kitchen

Washer

Resort Access - Lake - Pools -Pickleball - Gym. Spacious townhome for groups

Salem SC

With a stay at this vacation home in Salem, you'll be on a lake, within a 5-minute drive of Lake Keowee and Keowee Key Golf Course.

Pool

Hot Tub

Delightful 2-bedroom house with AC in charming Easley

Easley SC

With a stay at this vacation home in Easley, you'll be a 1-minute walk from Alice Mill Park and 6 minutes by foot from Hagood Park.

Kitchen

Washer

Four Seasons Private Suite on Chestnut Ridge in Highlands - Private Club Access

Highlands NC

Located in Highlands, this vacation home is in the mountains, within a 15-minute drive of Nantahala National Forest and Chattooga River.

Kitchen

Washer

Highland Hideaway 3BD-2BTH, Gameday Stadium-walkable, 82"TV/Pool Table/Firepit

Clemson SC

With a stay at this vacation home in Clemson, you'll be a 2-minute drive from Clemson University and 6 minutes from Memorial Stadium.

Kitchen

Washer

4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!

Seneca SC

With a stay at this vacation home in Seneca, you'll be on the waterfront, within a 15-minute drive of Lake Keowee and Keowee Key Golf Course.

Kitchen

Washer

Cozy 2-bedroom house on Lake Keowee with private dock

West Union SC

With a stay at this vacation home in West Union, you'll be on a lake, within a 15-minute drive of Lake Keowee and Art Circle Gallery.

Kitchen

Washer

Secluded cabin surrounded by mountains, waterfalls, wildlife, and 50,000 acres

Sunset SC

Located in Sunset, this vacation home is in the mountains, within a 15-minute drive of Eastatoe Creek Heritage Preserve and The Rock Golf Course And Resort.

Kitchen

Washer

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

Seneca SC

When you stay at this vacation home in Seneca, you'll be on the waterfront, within a 15-minute drive of Clemson University and Memorial Stadium.

Kitchen

Washer

Don't see what you're looking for?

See all available properties in Seneca

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.