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Featured Seneca Hotels with Shopping

Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd Seneca SC
$74 nightly
The price is $81 total per night
$81 total
Jun 18 - Jun 19
Total with taxes and fees
When you stay at Days Inn by Wyndham Seneca / Clemson Area in Seneca, you'll be in the business district, within a 15-minute drive of Lake Keowee and Clemson University.
Pool
Breakfast included

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
$86 nightly
The price is $94 total per night
$94 total
Jul 12 - Jul 13
Total with taxes and fees
Free Cancellation
With a stay at Quality Inn Seneca Clemson Area US-123, you'll be centrally located in Seneca, a 3-minute drive from Lake Keowee and 10 minutes from Clemson University.
Pool
Breakfast included

Best Western Seneca-Clemson
511 Bypass Highway 123 Seneca SC
$97 nightly
The price is $107 total per night
$107 total
Jun 18 - Jun 19
Total with taxes and fees
With a stay at Best Western Seneca-Clemson in Seneca, you'll be a 1-minute drive from Lake Keowee and 5 minutes from Lake Hartwell.
Pool
Breakfast included

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street Seneca SC
$119 nightly
The price is $131 total per night
$131 total
Jun 21 - Jun 22
Total with taxes and fees
When you stay at Hampton Inn & Suites Seneca-Clemson Area in Seneca, you'll be in the business district, within a 5-minute drive of Lake Keowee and Lake Hartwell.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Seneca hotels essential information
Accommodation | 1,662 hotels |
|---|---|
Lowest Price | $81 |
Highest Price | $131 |
Popular hotels | Days Inn by Wyndham Seneca / Clemson Area, Quality Inn Seneca Clemson Area US-123, Best Western Seneca-Clemson, Hampton Inn & Suites Seneca-Clemson Area |
Most Recent Seneca Hotel Reviews

Hampton Inn & Suites Seneca-Clemson Area
5 out of 5
Posted 7 hours ago
CheapTickets Verified Review
"This was my first stay at this location, and I can definitely say that I will be back. The staff was very kind and helpful before, during, and even after the stay. The hotel was very neat and clean, and the rooms were very comfy! The hotel is also in an area close to stores and other amenities."
A verified traveler stayed at Hampton Inn & Suites Seneca-Clemson Area
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