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Cheap O Brien Hotels
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
obrien FL
9.11 mi from city center
When you stay at this vacation home in O Brien, you'll be on the beach and steps from Suwannee River.
Kitchen
Washer
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
16367 NW 167TH BLVD Alachua FL
$113 nightly
The price is $127 total per night
$127 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
29.91 mi from city center
With a stay at Holiday Inn Express & Suites Alachua - Gainesville Area by IHG in Alachua, you'll be 10.4 mi (16.7 km) from Ruth B. Kirby Gilchrist Blue Springs State Park and 12.7 mi (20.4 km) from Devil's Milhopper Geological State Park.
Pool
Hot Tub
La Quinta Inn & Suite by Wyndham Lake City
165NW CALI DRIVE Lake City FL
$94 nightly
The price is $105 total per night
$105 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.21 mi from city center
With a stay at La Quinta Inn & Suite by Wyndham Lake City in Lake City, you'll be a 5-minute walk from Fresenius Medical Care at Lake City Medical Center and 5 minutes by foot from Lake City Medical Center.
Pool
Breakfast included
Tru by Hilton Lake City
284 NW Centurion Court Lake City FL
$100 nightly
The price is $113 total per night
$113 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
17.91 mi from city center
Located in Lake City, Tru by Hilton Lake City is within a 5-minute drive of Regal UA Cinema 90 and Fresenius Medical Care at Lake City Medical Center.
Pool
Breakfast included
Best Western Plus Lake City
350 SW Florida Gateway Dr Lake City FL
$87 nightly
The price is $98 total per night
$98 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
17.89 mi from city center
Located in Lake City, Best Western Plus Lake City is in the suburbs, within a 5-minute drive of Lake City Mall and Southside Recreation Complex.
Pool
Breakfast included
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
1699 NE Co Rd 337 High Springs FL
$139 nightly
The price is $153 total per night
$153 total
Dec 15 - Dec 16
Total with taxes and fees
24.65 mi from city center
Located in High Springs, Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy is in a regional park, within a 15-minute drive of Poe Springs Park and Santa Fe River.
Kitchen
Pet friendly
Motel 6 – Lake City, Fl – Medical Center
3340 W US Highway 90 Lake City FL
$52 nightly
The price is $59 total per night
$59 total
Dec 18 - Dec 19
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18 mi from city center
With a stay at Motel 6 – Lake City, Fl – Medical Center in Lake City, you'll be within a 10-minute walk of Fresenius Medical Care at Lake City Medical Center and Lake City Medical Center.
Pet friendly
Parking included
Holiday Inn Express & Suites Live Oak by IHG
6694 Us Highway 129 Live Oak FL
$121 nightly
The price is $133 total per night
$133 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
20.02 mi from city center
Located in Live Oak, Holiday Inn Express & Suites Live Oak by IHG is in a rural location, a 4-minute drive from Suwannee County Historical Museum and 6 minutes from Spirit of the Suwannee Music Park.
Pool
Breakfast included
Hampton Inn & Suites Lake City
450 SW Florida Gateway Drive Lake City FL
$87 nightly
The price is $98 total per night
$98 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
17.84 mi from city center
A stay at Hampton Inn & Suites Lake City places you in the heart of Lake City, within a 5-minute drive of Regal UA Cinema 90 and Fresenius Medical Care at Lake City Medical Center.
Pool
Breakfast included
Holiday Inn & Suites Lake City by IHG
213 Sw Commerce Dr Lake City FL
$95 nightly
The price is $107 total per night
$107 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
18.1 mi from city center
Located in Lake City, Holiday Inn & Suites Lake City by IHG is in a rural location, within a 15-minute walk of Fresenius Medical Care at Lake City Medical Center and Lake City Medical Center.
Pool
Pet friendly
Comfort Suites Lake City
3690 W Us Highway 90 Lake City FL
$108 nightly
The price is $121 total per night
$121 total
Dec 16 - Dec 17
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
17.73 mi from city center
A stay at Comfort Suites Lake City places you in the heart of Lake City, within a 15-minute walk of Fresenius Medical Care at Lake City Medical Center and Lake City Medical Center.
Pool
Breakfast included
Courtyard By Marriott Lake City
3004 West US HWY 90 Lake City FL
$107 nightly
The price is $120 total per night
$120 total
Dec 28 - Dec 29
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.24 mi from city center
With a stay at Courtyard By Marriott Lake City in Lake City, you'll be within a 5-minute drive of Lake City Mall and Southside Sports Complex.
Pool
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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O Brien hotels essential information
Accommodation | 347 hotels |
|---|---|
Lowest Price | $59 |
Highest Price | $153 |
Popular hotels | Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!, Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, La Quinta Inn & Suite by Wyndham Lake City, Tru by Hilton Lake City, Best Western Plus Lake City, Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy, Motel 6 – Lake City, Fl – Medical Center, Holiday Inn Express & Suites Live Oak by IHG, Hampton Inn & Suites Lake City, Holiday Inn & Suites Lake City by IHG, Comfort Suites Lake City, Courtyard By Marriott Lake City |
Most Recent O Brien Hotel Reviews
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
5 out of 5
Posted 4 days ago
CheapTickets Verified Review
"Great Property for Families "
A verified traveler from Plantation stayed at Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
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