Compare Cheap Hotels in Effingham
Secret Bargains - Save an extra 10% or more on select hotels
Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Cheap Effingham Hotels

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
$62 nightly
The price is $70 total per night
$70 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
12.27 mi from city center
When you stay at Howard Johnson by Wyndham Florence in Florence, you'll be near the airport and within a 5-minute drive of Dr. Eddie Floyd Tennis Center.
Breakfast included
Parking included

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
$85 nightly
The price is $95 total per night
$95 total
Dec 23 - Dec 24
Total with taxes and fees
Free Cancellation
12.2 mi from city center
When you stay at Park Inn by Radisson Florence, SC in Florence, you'll be near the airport and within a 5-minute drive of Dr. Eddie Floyd Tennis Center.
Breakfast included
Pet friendly

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
$99 nightly
The price is $110 total per night
$110 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
9.89 mi from city center
Located in Florence, Comfort Inn & Suites Florence Center Area is within a 5-minute drive of Florence Civic Center and Magnolia Mall.
Pool
Breakfast included

Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
$100 nightly
The price is $112 total per night
$112 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
9.41 mi from city center
A stay at Hyatt Place Florence Downtown places you in the heart of Florence, within a 10-minute walk of Pee Dee Mental Health Center and Drs Bruce and Lee Foundation Library.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St Florence SC
$89 nightly
The price is $100 total per night
$100 total
Dec 24 - Dec 25
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
12.42 mi from city center
Located in Florence, La Quinta Inn & Suites by Wyndham Florence is within a 10-minute drive of Mcleod Regional Medical Center and Florence Civic Center.
Pool
Breakfast included

Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $119 total per night
$119 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.08 mi from city center
With a stay at Home2 Suites by Hilton Florence, SC in Florence, you'll be within a 5-minute walk of Regal Swamp Fox and Florence Civic Center.
Pool
Breakfast included

Tru by Hilton Florence I-95
2140 West Lucas Street Florence SC
$97 nightly
The price is $108 total per night
$108 total
Dec 24 - Dec 25
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
12.51 mi from city center
Located in Florence, Tru by Hilton Florence I-95 is a 3-minute drive from Dr. Eddie Floyd Tennis Center and 6 minutes from Pee Dee Mental Health Center.
Pool
Breakfast included

Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road Florence SC
$113 nightly
The price is $127 total per night
$127 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
12.39 mi from city center
Located in Florence, Hampton Inn & Suites Florence-North-I-95 is in a shopping district, a 3-minute drive from Dr. Eddie Floyd Tennis Center and 6 minutes from Pee Dee Mental Health Center.
Pool
Hot Tub

Residence Inn Marriott Florence
2660 Hospitality Blvd Florence SC
$99 nightly
The price is $111 total per night
$111 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.09 mi from city center
With a stay at Residence Inn Marriott Florence in Florence, you'll be within a 10-minute walk of Florence Civic Center and Florence Veterans Park.
Pool
Breakfast included

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
$81 nightly
The price is $90 total per night
$90 total
Dec 24 - Dec 25
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.5 mi from city center
With a stay at Quality Inn & Suites Florence Civic Center, you'll be centrally located in Florence, just a 4-minute walk from Magnolia Mall and 13 minutes by foot from Florence Civic Center.
Pool
Breakfast included

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard Florence SC
$99 nightly
The price is $111 total per night
$111 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10 mi from city center
With a stay at TownePlace Suites by Marriott Florence in Florence, you'll be a 1-minute walk from Florence Veterans Park and 9 minutes by foot from Florence Civic Center.
Pool
Breakfast included

Staybridge Suites Florence - Civic Center by IHG
150 Westpark Drive Florence SC
$125 nightly
The price is $140 total per night
$140 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
10.28 mi from city center
Located in Florence, Staybridge Suites Florence - Civic Center by IHG is within a 15-minute walk of Florence Civic Center and Florence Veterans Park.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Often, one of the most difficult things about booking a hotel is finding the best time to go. The cost of staying in hotels in could vary significantly, depending on the time of the year chosen. If you would like to figure out the most suitable time to take a trip then using CheapTickets could be the best option for you. We will be able to provide information on hotels in to ensure that you get the best deal possible. So if you are looking for a booking website that will streamline the process and offer good prices, then log in and get booking.
Effingham hotels essential information
Accommodation | 138 hotels |
|---|---|
Lowest Price | $70 |
Highest Price | $140 |
Popular hotels | Howard Johnson by Wyndham Florence, Park Inn by Radisson Florence, SC, Comfort Inn & Suites Florence Center Area, Hyatt Place Florence Downtown, La Quinta Inn & Suites by Wyndham Florence, Home2 Suites by Hilton Florence, SC, Tru by Hilton Florence I-95, Hampton Inn & Suites Florence-North-I-95, Residence Inn Marriott Florence, Quality Inn & Suites Florence Civic Center, TownePlace Suites by Marriott Florence, Staybridge Suites Florence - Civic Center by IHG |
Most Recent Effingham Hotel Reviews

Residence Inn Marriott Florence
5 out of 5
Posted 20 hours ago
CheapTickets Verified Review
"Had a good stay for the price. Breakfast options seems limited but may be that's a standard for the area"
A verified traveler stayed at Residence Inn Marriott Florence
More to Explore in Effingham
Top Picks
Hotels
- Hotels in Anderson
- Hotels in North Charleston
- Hotels in Sullivan's Island
- Hotels in Clemson
- Hotels in Mount Pleasant
- Hotels in Summerville
- Hotels in Surfside Beach
- Hotels in Charleston
- Hotels in Myrtle Beach
- Hotels in Greenville
- Hotels in Pawleys Island
- Hotels in Columbia
- Hotels in Daufuskie Island
- Hotels in Kiawah Island
- Hotels in Folly Beach
- 4 Star Hotels in Myrtle Beach
- Hotels in North Myrtle Beach
Flights






