Cape Girardeau Vacation Rentals

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Vacation Rentals in Cape Girardeau

On the Wine Trail - Minutes to Giant City, Shawnee Forest, SIU - Amazing Shower

Alto Pass IL

With a stay at this vacation home in Alto Pass, you'll be a 1-minute walk from Shawnee National Forest and 15 minutes by foot from Peachbarn Winery.

Kitchen

Washer

* On the Wine Trail * Hot Tub * Wi-Fi *

Alto Pass IL

With a stay at this vacation home, you'll be centrally located in Alto Pass, steps from Shawnee National Forest and 15 minutes by foot from Peachbarn Winery.

Hot Tub

Kitchen

Notting Hill Cottage

Alto Pass IL

With a stay at this vacation home in Alto Pass, you'll be a 1-minute drive from Shawnee National Forest and 6 minutes from Peachbarn Winery.

Hot Tub

Kitchen

Sip, Hike, Relax - A Private 20-Acre Haven in Wine Country

Alto Pass IL

With a stay at this vacation home in Alto Pass, you'll be steps from Shawnee National Forest and a 3-minute drive from Peachbarn Winery.

Hot Tub

Kitchen

Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen

Anna IL

With a stay at this vacation home, you'll be centrally located in Anna, within a 15-minute drive of Shawnee National Forest and Shawnee Community College.

Wine Trail, Cozy Cabin plus hot tub

Cobden IL

With a stay at this vacation home in Cobden, you'll be within a 10-minute drive of Shawnee National Forest and Owl Creek Vineyard.

Hot Tub

Kitchen

Sunset Ridge - Cabin 4

Cobden IL

With a stay at this vacation home in Cobden, you'll be steps from Shawnee National Forest and Rustle Hill Winery.

Hot Tub

Kitchen

Quaint, Beautiful Home next to SEMO and Hospital

Cape Girardeau MO

With a stay at this vacation home in Cape Girardeau, you'll be within a 5-minute drive of Mississippi River and Shawnee National Forest.

Beautiful location in the secluded woods

Pomona IL

$180 nightly

$191 total

Feb 16 - Feb 17

Total with taxes and fees

When you stay at this vacation home in Pomona, you'll be 1 minutes by foot from Shawnee National Forest.

Kitchen

Washer

* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *

Alto Pass IL

With a stay at this vacation home, you'll be centrally located in Alto Pass, steps from Shawnee National Forest and 15 minutes by foot from Peachbarn Winery.

Kitchen

Free WiFi

Magical Victorian near hiking / wine trail

Anna IL

$362 nightly

$401 total

Jan 20 - Jan 21

Total with taxes and fees

With a stay at this vacation home in Anna, you'll be within a 15-minute drive of Shawnee National Forest and Anna City Park.

Kitchen

Washer

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

Cape Girardeau MO

With a stay at this vacation home, you'll be centrally located in Cape Girardeau, within a 5-minute drive of Mississippi River and Shawnee National Forest.

Don't see what you're looking for?

See all available properties in Cape Girardeau

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.