Best Flight From Detroit Metropolitan Wayne County To ROA

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Amazing DTW to ROA Flight Deals

The cheapest flights to Roanoke Regional were $349 for round trip flights and $392 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 22 - Tue, Sep 29
DTW
Detroit
ROA
Roanoke
$349 Roundtrip, found 5 hours ago
$349
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Sep 22 from Detroit to Roanoke, returning Tue, Sep 29, priced at $349 found 5 hours ago
Tue, Sep 22 - Tue, Sep 29
DTW
Detroit
ROA
Roanoke
$369 Roundtrip, found 5 hours ago
$369
Roundtrip
found 5 hours ago
Select United flight, departing Tue, Sep 22 from Detroit to Roanoke, returning Tue, Sep 29, priced at $369 found 5 hours ago
Tue, Sep 22 - Tue, Sep 29
DTW
Detroit
ROA
Roanoke
$393 Roundtrip, found 5 hours ago
$393
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Sep 22 from Detroit to Roanoke, returning Tue, Sep 29, priced at $393 found 5 hours ago
Tue, Sep 22 - Tue, Sep 29
DTW
Detroit
ROA
Roanoke
$396 Roundtrip, found 5 hours ago
$396
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Sep 22 from Detroit to Roanoke, returning Tue, Sep 29, priced at $396 found 5 hours ago
Tue, Sep 22 - Tue, Sep 29
DTW
Detroit
ROA
Roanoke
$413 Roundtrip, found 5 hours ago
$413
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Sep 22 from Detroit to Roanoke, returning Tue, Sep 29, priced at $413 found 5 hours ago
Tue, Sep 22 - Tue, Sep 29
DTW
Detroit
ROA
Roanoke
$416 Roundtrip, found 5 hours ago
$416
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Sep 22 from Detroit to Roanoke, returning Tue, Sep 29, priced at $416 found 5 hours ago

Hotels near Roanoke Regional Airport (ROA)

Spark by Hilton Roanoke Airport

Spark by Hilton Roanoke Airport

3 out of 5
3695 Thirlane Rd Nw Roanoke VA
$73 nightly
The price is $83 total per night from Sep 21 to Sep 22
$83 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and a free airport shuttle. Popular attractions Valley View Mall and Regal Valley View Grande are located nearby.
8.8/10 Excellent! (529 reviews)
"Front desk attendant was more concerned with her phone than the guests"

Reviewed on Sep 11, 2026

Opens in a new windowSpark by Hilton Roanoke Airport
Comfort Inn Airport

Comfort Inn Airport

2.5 out of 5
5070 Valley View Blvd Nw Roanoke VA
$85 nightly
The price is $97 total per night from Oct 4 to Oct 5
$97 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Valley View Mall and AMF Hilltop Lanes are located nearby.
8.6/10 Excellent! (937 reviews)
"Easy check in. Clean room. Close to restaurants."

Reviewed on Sep 11, 2026

Opens in a new windowComfort Inn Airport
Country Inn & Suites by Radisson, Roanoke, VA

Country Inn & Suites by Radisson, Roanoke, VA

3 out of 5
7860 Plantation Rd Roanoke VA
$92 nightly
The price is $104 total per night from Oct 11 to Oct 12
$104 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Eleanor D. Wilson Museum and Richard Wetherill Visual Arts Center are located nearby.
9/10 Wonderful! (2,454 reviews)
"Great one night stay!"

Reviewed on Sep 12, 2026

Opens in a new windowCountry Inn & Suites by Radisson, Roanoke, VA
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Best Western Plus Inn at Valley View

Best Western Plus Inn at Valley View

2.5 out of 5
5050 Valley View Boulevard Northwest Roanoke VA
$73 nightly
The price is $83 total per night from Sep 27 to Sep 28
$83 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Valley View Mall and Regal Valley View Grande are located nearby.
8.2/10 Very Good! (1,001 reviews)
"Very clean and in a good location spacious room"

Reviewed on Sep 11, 2026

Opens in a new windowBest Western Plus Inn at Valley View
Hyatt Place Roanoke Airport/Valley View Mall

Hyatt Place Roanoke Airport/Valley View Mall

3 out of 5
5040 Valley View Blvd North Roanoke VA
$118 nightly
The price is $134 total per night from Sep 27 to Sep 28
$134 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Valley View Mall and Regal Valley View Grande are located nearby.
Opens in a new windowHyatt Place Roanoke Airport/Valley View Mall
Quality Inn Roanoke Airport

Quality Inn Roanoke Airport

2.5 out of 5
6626 Thirlane Rd Roanoke VA
$81 nightly
The price is $91 total per night from Sep 20 to Sep 21
$91 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Splash Valley at Green Ridge Recreation Center and AMF Hilltop Lanes are located nearby.
Opens in a new windowQuality Inn Roanoke Airport
Super 8 by Wyndham Roanoke VA

Super 8 by Wyndham Roanoke VA

2 out of 5
6616 Thirlane Rd Roanoke VA
$51 nightly
The price is $57 total per night from Sep 20 to Sep 21
$57 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Splash Valley at Green Ridge Recreation Center and AMF Hilltop Lanes are located nearby.
Opens in a new windowSuper 8 by Wyndham Roanoke VA
Hampton Inn & Suites Roanoke Airport

Hampton Inn & Suites Roanoke Airport

2.5 out of 5
5033 Valley View Boulevard NW Roanoke VA
$111 nightly
The price is $125 total per night from Sep 20 to Sep 21
$125 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in Roanoke. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Valley View Mall and Regal Valley View Grande are located nearby.
Opens in a new windowHampton Inn & Suites Roanoke Airport
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Picks

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.