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Lowest round trip fares by airline from Des Moines and Phoenix

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Cheap flights from Des Moines to Phoenix

Cheap flights from Des Moines to Phoenix

Air travel from Des Moines International Airport (DSM) to Phoenix Sky Harbor International Airport (PHX), gives travelers an aerial view over dozens of landscapes; including mountains, plains, waterways and deserts. Visitors traveling for business may not have much time to get out of Phoenix, but there are still plenty of sights to see downtown. CityScape is a grand courtyard that links live music, quaint retail shops, and major dining attractions.

Key Facts

Interstates 10 and 17 make it an easy drive to Mesa, Chandler and Surprise, which all feature interesting opportunities for visitors to experience life on a ranch, hike on a rocky mountain, or visit some beautiful Southwestern style homes.

The Apache Trail is worth the four-hour drive from Phoenix, and the scenery along the way is more than pleasant. Those who stay close to the city center can check out a Phoenix Suns or Arizona Cardinals game, depending on the season. The Orpheum Theater and the Pueblo Grand Indian Market, both provide local culture and history lessons, as well as artifacts for visitors to peruse.

Hints and Tips

Nonstop flights from DSM to PHX are about three hours long. Connecting flights to thousands of worldwide destinations are made daily from PHX, so expect it to be busy. Rental cars from PHX allow visitors to take in many splendors, including fine dining and nightlife, such as Gallo Blanco. Country music can often be heard from stadiums, street corners and local diners.

Packages from Des Moines to Phoenix

Phoenix vacations with economy flights

Hotels in Phoenix

See all 5,787 Properties in Phoenix
Talking Stick Resort

Talking Stick Resort

9800 E. Talking Stick Way, Scottsdale, AZ
    4.0 out of 5.0
     
     
    4.5 out of 5 (38 reviews)

    This family-friendly Scottsdale resort is located in the mountains, within 2 mi (3 km) of Butterfly Wonderland, OdySea Aquarium, and Salt River Fields at Talking ...

    Talking Stick Resort$149

    Talking Stick Resort$149
    SureStay Hotel by Best Western Phoenix Airport

    SureStay Hotel by Best Western Phoenix Airport

    3037 E Van Buren St, Phoenix, AZ
      2.0 out of 5.0
       
       
      3.3 out of 5 (30 reviews)

      Located in Downtown Phoenix, this hotel is 0.4 mi (0.7 km) from Celebrity Theater and within 6 mi (10 km) of Phoenix Convention Center and Chase Field. Talking ...

      SureStay Hotel by Best Western Phoenix Airport$54

      SureStay Hotel by Best Western Phoenix Airport$54
      Arizona Grand Resort

      Arizona Grand Resort

      8000 S. Arizona Grand Parkway, Phoenix, AZ
        4.0 out of 5.0
         
         
        4.1 out of 5 (34 reviews)

        This family-friendly Phoenix resort is located in the suburbs, within a 15-minute walk of Oasis Water Park and Arizona Mills Mall. Diablo Stadium is 2.5 mi (4 ...

        Arizona Grand Resort$179

        Arizona Grand Resort$179
        3 Palms

        3 Palms

        7707 E McDowell Rd, Scottsdale, AZ
          3.5 out of 5.0
           
           
          3.9 out of 5 (98 reviews)

          Located in South Scottsdale, this hotel is within 3 mi (5 km) of Big Surf, Desert Botanical Garden, and Scottsdale Stadium. Scottsdale Healthcare Osborn Medical ...

          3 Palms$51

          3 Palms$51
          The Scottsdale Resort at McCormick Ranch

          The Scottsdale Resort at McCormick Ranch

          7700 E Mccormick Pkwy, Scottsdale, AZ
            4.0 out of 5.0
             
             
            4.1 out of 5 (16 reviews)

            Located in South Scottsdale, this spa resort is 2.2 mi (3.5 km) from Salt River Fields at Talking Stick and 2.7 mi (4.3 km) from OdySea Aquarium. Butterfly Wonderland ...

            The Scottsdale Resort at McCormick Ranch$149

            The Scottsdale Resort at McCormick Ranch$149
            Scottsdale Plaza Resort

            Scottsdale Plaza Resort

            7200 N Scottsdale Rd, Scottsdale, AZ
              4.0 out of 5.0
               
               
              4.0 out of 5 (23 reviews)

              Located in South Scottsdale, this spa resort is within 3 mi (5 km) of Old Town, Salt River Fields at Talking Stick, and Scottsdale Fashion Square. Camelback ...

              Scottsdale Plaza Resort$139

              Scottsdale Plaza Resort$139
              Country Inn & Suites by Radisson, Phoenix Airport, AZ

              Country Inn & Suites by Radisson, Phoenix Airport, AZ

              4702 E University Dr, Phoenix, AZ
                3.0 out of 5.0
                 
                 
                4.2 out of 5 (6 reviews)

                Located in South Mountain, this hotel is within 3 mi (5 km) of Tempe Center for the Arts, Grady Gammage Memorial Auditorium, and Tempe Town Lake. Diablo Stadium ...

                Country Inn & Suites by Radisson, Phoenix Airport, AZ$73

                Country Inn & Suites by Radisson, Phoenix Airport, AZ$73
                Omni Scottsdale Resort & Spa at Montelucia

                Omni Scottsdale Resort & Spa at Montelucia

                4949 E Lincoln Drive, Paradise Valley, AZ
                  5.0 out of 5.0
                   
                   
                  4.7 out of 5 (3 reviews)

                  Situated in the suburbs, this luxury resort is 1.9 mi (3.1 km) from Camelback Mountain and within 6 mi (10 km) of Scottsdale Fashion Square and Biltmore Fashion ...

                  Omni Scottsdale Resort & Spa at Montelucia$259

                  Omni Scottsdale Resort & Spa at Montelucia$259
                  Baymont by Wyndham Phoenix I-10 near 51st Ave

                  Baymont by Wyndham Phoenix I-10 near 51st Ave

                  1242 N 53rd Avenue, Phoenix, AZ
                    2.5 out of 5.0
                     
                     
                    4.5 out of 5 (2 reviews)

                    Located in Estrella, this hotel is 2.6 mi (4.1 km) from Maryvale Baseball Park and within 6 mi (10 km) of Ashley Furniture HomeStore Pavilion and Arizona State ...

                    Baymont by Wyndham Phoenix I-10 near 51st Ave$55

                    Baymont by Wyndham Phoenix I-10 near 51st Ave$55
                    Hyatt Regency Scottsdale Resort and Spa at Gainey Ranch

                    Hyatt Regency Scottsdale Resort and Spa at Gainey Ranch

                    7500 E Doubletree Ranch Rd, Scottsdale, AZ
                      4.5 out of 5.0
                       
                       
                      4.4 out of 5 (15 reviews)

                      Located in South Scottsdale, this luxury resort is 2.5 mi (4 km) from Salt River Fields at Talking Stick and 3 mi (4.9 km) from OdySea Aquarium. Butterfly Wonderland ...

                      Hyatt Regency Scottsdale Resort and Spa at Gainey Ranch$299

                      Hyatt Regency Scottsdale Resort and Spa at Gainey Ranch$299
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                      *Savings based on all holiday package bookings with Flight + Hotel on CheapTickets.com from January through December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

                      *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.