Cheap flights from St. Louis (STL) to Santo Domingo (SDQ)

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Lowest round trip fares by airline from St. Louis and Santo Domingo

Cheapest prices ( One Way, $305 Round Trip) found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Great Deals On Cheap Hotels in Santo Domingo

Be Live Experience Hamaca Beach

Be Live Experience Hamaca Beach

3.5 out of 5
Calle Duarte #1-B Esq. Caracol, Boca Chica, Santo Domingo, 15700
The price is $60 per night from Jan 31 to Feb 1
$60
per night
Jan 31 - Feb 1
Stay at this 3.5-star beach hotel in Boca Chica. Enjoy free parking, 2 outdoor pools, and 2 restaurants. Our guests praise the convenient parking and the family ...
2.5/5 (1,026 reviews)
"Me encanto el lugar en general el servició de todos el desayuno ufff riquísimo y un cafe negro como si yo lo uniera echo en casa se lo recomiendo picina chalada la playa hay mismo"

Reviewed on Jan 28, 2023

Be Live Experience Hamaca Beach
Be Live Experience Hamaca Suites

Be Live Experience Hamaca Suites

3.5 out of 5
Calle Duarte #1-C, Esq. Caracol, Boca Chica, Santo Domingo, 15700
The price is $77 per night from Jan 31 to Feb 1
$77
per night
Jan 31 - Feb 1
Stay at this 3.5-star beach hotel in Boca Chica. Enjoy free parking, 2 outdoor pools, and 2 restaurants. Our guests praise the helpful staff and the comfy rooms ...
2.3/5 (441 reviews)
"I love it"

Reviewed on Dec 29, 2022

Be Live Experience Hamaca Suites
Plaza Real Resort

Plaza Real Resort

3 out of 5
Avenida Boulevard, Villas del Mar, Guayacanes, San Pedro de Macoris, 21000
The price is $34 per night from Mar 1 to Mar 2
$34
per night
Mar 1 - Mar 2
Stay at this 3-star beach aparthotel in Guayacanes. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the pool and the helpful staff in our ...
3.3/5 (579 reviews)
"Staff was very nice, and were able to accommodate my requests to switch rooms because of a better room safer for my toddler girl. Room was comfortable and pleasing it even included a little stove, fridge, sink, kitchen cabinets, pots, pans, and plates to cook, and round dinning table with chairs, ..."

Reviewed on Jan 9, 2023

Plaza Real Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fly From St. Louis to Santo Domingo

Origin St. Louis
Destination Santo Domingo
Number of Daily Flights
Earliest Flight Departure Date
Latest Flight Departure Date
Popular Airlines

Cheap flights from St. Louis to Santo Domingo

Are you ready to book your flight, but feeling nervous about paying too much if prices drop in a few days? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus $50 more in CheapCash, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a Santo Domingo Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Santo Domingo vacation that you can't get when you book flights and hotel separately.

Relax in Santo Domingo With Confidence and Convenience

Going cheap doesn't mean giving up great service. Our agents are available 24/7 to help you find the right cheap flights and hotel, and to answer questions about your trip.

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.