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Lowest round trip fares by airline from San Francisco and St. Louis

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Cheap flights from San Francisco to St. Louis

Cheap flights from San Francisco to St Louis

Leave your car safely in the carport and head to San Francisco International (SFO) on the BART Rapid Rail or the Caltrain Commuter Rail. Grab a drink and sit back while in air, as typical flight times are just under three-and-a-half hours. When you land at Lambert-St Louis International (STL), climb on the Light Rail or pick up a rental car and drive yourself into St. Louis proper.

Attractions

Get a feel for downtown St. Louis with a tour of The Loop. This six-block neighborhood houses an assortment of cafes and stores to explore. To commune with nature, head over to Forest Park. Tourists and local alike enjoy spending time in this sprawling 1,300-acre greenspace, prized for its place as a relaxing escape from the city. Gaze at the Gateway Arch, the monument for which St. Louis is best known, which remains a reminder of the impact of Westward expansion. Make a stop at the St. Louis Zoo and spend time with the amazing animals that call it home.

Hints and tips

For easy access to galleries and boutiques, stay in Chesterfield, or if you plan on attending to business during your visit, make Downtown St. Louis your jumping-off point. Temperatures vary seasonally in St. Louis. For easiest access to the outdoor activities, for which this region is popular, visit June through September when you will enjoy the warmest temperatures.

Packages from San Francisco to St. Louis

St. Louis vacations with economy flights

Hotels in St. Louis

See all 526 Properties in St. Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis, MO
    4.0 out of 5.0
     
     
    4.4 out of 5 (30 reviews)

    Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse and Gateway Arch. Dome at America’s Center and Busch Stadium are also ...

    Hyatt Regency St. Louis at The Arch$139

    Hyatt Regency St. Louis at The Arch$139
    Drury Plaza Hotel St. Louis at the Arch

    Drury Plaza Hotel St. Louis at the Arch

    2 South 4th Street, St. Louis, MO
      3.0 out of 5.0
       
       
      4.3 out of 5 (11 reviews)

      Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse, Gateway Arch, and Busch Stadium. Dome at America’s Center and America's ...

      Drury Plaza Hotel St. Louis at the Arch$135

      Drury Plaza Hotel St. Louis at the Arch$135
      Clayton Plaza Hotel

      Clayton Plaza Hotel

      7750 Carondelet Avenue, St. Louis, MO
        3.5 out of 5.0
         
         
        4.1 out of 5 (12 reviews)

        Located in Downtown, this hotel is 0.2 mi (0.3 km) from Plaza Clayton and within 3 mi (5 km) of Washington University and Forest Park. St. Louis Art Museum and ...

        Clayton Plaza Hotel$104

        Clayton Plaza Hotel$104
        Marriott St. Louis Airport

        Marriott St. Louis Airport

        10700 Pear Tree Lane, St. Louis, MO
          3.5 out of 5.0
           
           
          3.9 out of 5 (22 reviews)

          Located in Airport Township, this hotel is within 6 mi (10 km) of St. Louis Mercantile Library, Westport Plaza, and Blanche M. Touhill Performing Arts Center. ...

          Marriott St. Louis Airport$90

          Marriott St. Louis Airport$90
          Hollywood Casino & Hotel St. Louis

          Hollywood Casino & Hotel St. Louis

          777 Casino Center Drive, Maryland Heights, MO
            3.5 out of 5.0
             
             
            3.9 out of 5 (12 reviews)

            Situated near the airport, this hotel is 1.4 mi (2.2 km) from Hollywood Casino Amphitheatre and within 9 mi (15 km) of Historic Main Street and Lindenwood University. ...

            Hollywood Casino & Hotel St. Louis$84

            Hollywood Casino & Hotel St. Louis$84
            Marriott St. Louis Grand

            Marriott St. Louis Grand

            800 Washington Ave, St. Louis, MO
              4.0 out of 5.0
               
               
              5.0 out of 5 (1 reviews)

              Located in Downtown St. Louis, this romantic hotel is steps from Washington Avenue Historic District and America's Center Convention Complex. Dome at America’s ...

              Marriott St. Louis Grand$139

              Marriott St. Louis Grand$139
              La Quinta Inn & Suites by Wyndham St Louis Airport-Riverport

              La Quinta Inn & Suites by Wyndham St Louis Airport-Riverport

              13615 Riverport Drive, I-70 & Earth City Expswy, Maryland Heights, MO
                3.0 out of 5.0
                 
                 
                4.6 out of 5 (7 reviews)

                Situated near the airport, this hotel is 0.6 mi (1 km) from Hollywood Casino Amphitheatre and within 6 mi (10 km) of Family Arena and Westport Plaza. Historic ...

                La Quinta Inn & Suites by Wyndham St Louis Airport-Riverport$87

                La Quinta Inn & Suites by Wyndham St Louis Airport-Riverport$87
                Hilton St. Louis at the Ballpark

                Hilton St. Louis at the Ballpark

                1 S Broadway, St. Louis, MO
                  4.0 out of 5.0
                   
                   
                  4.0 out of 5 (14 reviews)

                  Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse, Busch Stadium, and Gateway Arch. America's Center Convention Complex ...

                  Hilton St. Louis at the Ballpark$140

                  Hilton St. Louis at the Ballpark$140
                  Pear Tree Inn St. Louis Near Union Station

                  Pear Tree Inn St. Louis Near Union Station

                  2211 Market Street, St. Louis, MO
                    3.0 out of 5.0
                     
                     
                    4.4 out of 5 (5 reviews)

                    Located in Downtown St. Louis, this hotel is within 1 mi (2 km) of Washington Avenue Historic District, Enterprise Center, and City Museum. America's Center ...

                    Pear Tree Inn St. Louis Near Union Station$110

                    Pear Tree Inn St. Louis Near Union Station$110
                    HoteLumiere at the Arch

                    HoteLumiere at the Arch

                    999 N. 2nd St., St. Louis, MO
                      4.0 out of 5.0
                       
                       
                      3.0 out of 5 (3 reviews)

                      Located in Downtown St. Louis, this hotel is within a 10-minute walk of Laclede's Landing and Dome at America’s Center. America's Center Convention Complex and ...

                      HoteLumiere at the Arch$129

                      HoteLumiere at the Arch$129
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                      *Savings based on all holiday package bookings with Flight + Hotel on CheapTickets.com from January through December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

                      *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.