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Lowest round trip fares by airline from Houston and St. Louis

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Cheap flights from Houston to St. Louis

Cheap flights from Houston to St. Louis

Are you ready to book your flight, but feeling nervous about paying too much if the price drops? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus a $50 CheapCash bonus, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a St. Louis Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your St. Louis vacation that you can't get when you book flights and hotel separately.

Relax in St. Louis With Confidence and Convenience

Going cheap doesn't mean giving up great service. Our agents are available 24/7 to help you find the right cheap flights and hotel, and to answer questions about your trip.

Need to grab a cheap travel deal while you're on the go? Download our mobile app, where you can search and book just like you would on your home computer. Stay in-the-know on great rates on flights from Houston to St. Louis by signing up for exclusive email deals.

Hotels in St. Louis

See all 619 Properties in St. Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis, MO
    4.0 out of 5.0
     
     
    4.4 out of 5 (30 reviews)

    Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse and Gateway Arch. Dome at America’s Center and Busch Stadium are also ...

    Hyatt Regency St. Louis at The Arch$89

    Hyatt Regency St. Louis at The Arch$89
    Hollywood Casino & Hotel St. Louis

    Hollywood Casino & Hotel St. Louis

    777 Casino Center Drive, Maryland Heights, MO
      3.5 out of 5.0
       
       
      3.9 out of 5 (12 reviews)

      Situated near the airport, this hotel is 1.4 mi (2.2 km) from Hollywood Casino Amphitheatre and within 9 mi (15 km) of Historic Main Street and Lindenwood University. ...

      Hollywood Casino & Hotel St. Louis$84

      Hollywood Casino & Hotel St. Louis$84
      Drury Plaza Hotel St. Louis at the Arch

      Drury Plaza Hotel St. Louis at the Arch

      2 South 4th Street, St. Louis, MO
        3.0 out of 5.0
         
         
        4.3 out of 5 (12 reviews)

        Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse, Gateway Arch, and Busch Stadium. Dome at America’s Center and America's ...

        Drury Plaza Hotel St. Louis at the Arch$114

        Drury Plaza Hotel St. Louis at the Arch$114
        Hilton St. Louis at the Ballpark

        Hilton St. Louis at the Ballpark

        1 S Broadway, St. Louis, MO
          4.0 out of 5.0
           
           
          4.0 out of 5 (14 reviews)

          Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse, Busch Stadium, and Gateway Arch. America's Center Convention Complex ...

          Hilton St. Louis at the Ballpark$91

          Hilton St. Louis at the Ballpark$91
          The Parkway Hotel

          The Parkway Hotel

          4550 Forest Park Ave, St. Louis, MO
            3.0 out of 5.0
             
             
            4.5 out of 5 (4 reviews)

            Located in Central West End, this hotel is within a 10-minute walk of Forest Park, Barnes Jewish Hospital, and World Chess Hall of Fame. Cathedral Basilica of ...

            The Parkway Hotel$101

            The Parkway Hotel$101
            Pear Tree Inn St. Louis Near Union Station

            Pear Tree Inn St. Louis Near Union Station

            2211 Market Street, St. Louis, MO
              3.0 out of 5.0
               
               
              4.4 out of 5 (5 reviews)

              Located in Downtown St. Louis, this hotel is within 1 mi (2 km) of Washington Avenue Historic District, Enterprise Center, and City Museum. America's Center ...

              Pear Tree Inn St. Louis Near Union Station$90

              Pear Tree Inn St. Louis Near Union Station$90
              Drury Inn St. Louis at Union Station

              Drury Inn St. Louis at Union Station

              201 S 20th St, St. Louis, MO
                3.0 out of 5.0
                 
                 
                5.0 out of 5 (3 reviews)

                Located in Downtown St. Louis, this hotel is within a 10-minute walk of Washington Avenue Historic District and Enterprise Center. City Museum and Busch Stadium ...

                Drury Inn St. Louis at Union Station$104

                Drury Inn St. Louis at Union Station$104
                Ameristar Casino Resort and Spa (St. Charles)

                Ameristar Casino Resort and Spa (St. Charles)

                1 Ameristar Blvd, St. Charles, MO
                  4.5 out of 5.0
                   
                   
                  4.4 out of 5 (5 reviews)

                  Located in the heart of St. Charles, this luxury hotel is within 3 mi (5 km) of Lindenwood University, Family Arena, and Katy Trail. Jaycee Park and Hollywood ...

                  Ameristar Casino Resort and Spa (St. Charles)$87

                  Ameristar Casino Resort and Spa (St. Charles)$87
                  Marriott St. Louis Airport

                  Marriott St. Louis Airport

                  10700 Pear Tree Lane, St. Louis, MO
                    3.5 out of 5.0
                     
                     
                    3.9 out of 5 (22 reviews)

                    Located in Airport Township, this hotel is within 6 mi (10 km) of St. Louis Mercantile Library, Westport Plaza, and Blanche M. Touhill Performing Arts Center. ...

                    Marriott St. Louis Airport$117

                    Marriott St. Louis Airport$117
                    Hilton St. Louis Downtown at the Arch

                    Hilton St. Louis Downtown at the Arch

                    400 Olive St, St. Louis, MO
                      4.0 out of 5.0
                       
                       
                      4.0 out of 5 (10 reviews)

                      Located in Downtown St. Louis, this romantic hotel is within a 10-minute walk of Security Building, Dome at America’s Center, and America's Center Convention ...

                      Hilton St. Louis Downtown at the Arch$92

                      Hilton St. Louis Downtown at the Arch$92
                      Map

                      *Savings based on all holiday package bookings with Flight + Hotel on CheapTickets.com from January through December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

                      *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.