Compare Boutique Hotels in Southwest Houston

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Featured Southwest Houston Boutique Hotels

The St. Regis Houston

The St. Regis Houston

5 out of 5
1919 Briar Oaks Ln Houston TX
$375 nightly
The price is $439 total per night
$439 total
Dec 28 - Dec 29
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Houston (The Galleria), The St. Regis Houston is within a 15-minute drive of Houston Zoo and Toyota Center.
Pool
Spa
Hotel Ylem

Hotel Ylem

3.5 out of 5
8080 S Main St Houston TX
$76 nightly
The price is $89 total per night
$89 total
Dec 24 - Dec 25
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
In the heart of Houston, Hotel Ylem is within a 5-minute drive of NRG Park and MD Anderson Cancer Center.
Breakfast included
Parking included
Hotel Granduca Houston

Hotel Granduca Houston

4 out of 5
1080 Uptown Park Blvd Houston TX
$338 nightly
The price is $396 total per night
$396 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Houston (The Galleria), Hotel Granduca Houston is within a 15-minute drive of Rice University and Houston Zoo.
Pool
Hot Tub
Hotel Derek

Hotel Derek

4 out of 5
2525 West Loop S Houston TX
With a stay at Hotel Derek in Houston (The Galleria), you'll be a 1-minute drive from Westheimer Road and 8 minutes from Rice University.
Pet friendly
Free WiFi
Hotel Vesper, Houston, a Tribute Portfolio Hotel

Hotel Vesper, Houston, a Tribute Portfolio Hotel

2.5 out of 5
5160 Hidalgo St Houston TX
$111 nightly
The price is $130 total per night
$130 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hotel Vesper, Houston, a Tribute Portfolio Hotel, you'll be centrally located in Houston, a 1-minute drive from Westheimer Road and 8 minutes from Rice University.
Pet friendly
Free WiFi
Aloft Houston by the Galleria

Aloft Houston by the Galleria

3 out of 5
5415 Westheimer Road Houston TX
$109 nightly
The price is $128 total per night
$128 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Aloft Houston by the Galleria, you'll be centrally located in Houston, a 1-minute drive from Westheimer Road and 8 minutes from Rice University.
Pool
Pet friendly
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Southwest Houston hotels essential information

Accommodation
1,348 hotels
Lowest Price
$89
Highest Price
$439
Popular hotels
The St. Regis Houston, Hotel Ylem, Hotel Granduca Houston, Hotel Derek, Hotel Vesper, Houston, a Tribute Portfolio Hotel, Aloft Houston by the Galleria

Most Recent Southwest Houston Hotel Reviews

Home2 Suites by Hilton at the Galleria

Home2 Suites by Hilton at the Galleria

5 out of 5
Posted 17 hours ago
CheapTickets Verified Review
"The hotel was staffed with very helpful associates and the room was nice and clean. "
A verified traveler stayed at Home2 Suites by Hilton at the Galleria
Home2 Suites by Hilton at the Galleria

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