Compare Cheap Hotels in Sikeston
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Cheap Sikeston Hotels

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
$95 nightly
The price is $108 total per night
$108 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.46 mi from city center
When you stay at Hampton Inn Sikeston in Sikeston, you'll be near the airport, within a 5-minute drive of Central Park and Sikeston Depot Museum.
Pool
Breakfast included

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$90 nightly
The price is $103 total per night
$103 total
Dec 18 - Dec 19
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
3.13 mi from city center
A stay at Drury Inn & Suites Sikeston, MO places you in the heart of Sikeston, a 1-minute drive from City of Miner Convention Center and 5 minutes from Sikeston Depot Museum.
Pool
Breakfast included

Best Western Plus Sikeston
120 S Interstate Drive Sikeston MO
$71 nightly
The price is $81 total per night
$81 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
3.35 mi from city center
Located in Sikeston, Best Western Plus Sikeston is a 2-minute drive from City of Miner Convention Center and 6 minutes from Sikeston Depot Museum.
Pool
Breakfast included

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
$55 nightly
The price is $63 total per night
$63 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
3.07 mi from city center
Located in Sikeston, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is in a rural location, within a 5-minute drive of City of Miner Convention Center and Sikeston Depot Museum.
Breakfast included
Pet friendly

Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
$75 nightly
The price is $86 total per night
$86 total
Dec 18 - Dec 19
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
3.06 mi from city center
A stay at Pear Tree Inn Sikeston places you in the heart of Sikeston, just a 4-minute walk from City of Miner Convention Center and within a 5-minute drive of Sikeston Depot Museum.
Pool
Hot Tub

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$63 nightly
The price is $72 total per night
$72 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
3.34 mi from city center
Located in Sikeston, Days Inn and Suites by Wyndham Sikeston is a 3-minute drive from City of Miner Convention Center and 7 minutes from Sikeston Depot Museum.
Breakfast included
Pet friendly

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
$101 nightly
The price is $114 total per night
$114 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.56 mi from city center
With a stay at Fairfield Inn & Suites by Marriott Sikeston in Sikeston, you'll be within a 5-minute drive of Central Park and Sikeston Depot Museum.
Pool
Breakfast included

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
$59 nightly
The price is $68 total per night
$68 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
2.87 mi from city center
With a stay at Super 8 by Wyndham Sikeston/Miner Area in Sikeston, you'll be within a 5-minute drive of City of Miner Convention Center and Sikeston Depot Museum.
Breakfast included
Pet friendly

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
$93 nightly
The price is $105 total per night
$105 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
1.41 mi from city center
Located in Sikeston, Holiday Inn Express & Suites Sikeston Southwest by IHG is in a rural location, within a 5-minute drive of Central Park and Sikeston Depot Museum.
Pool
Breakfast included

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night
$102 total
Dec 18 - Dec 19
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
29.57 mi from city center
With a stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Hot Tub

The Riverview
777 Main St Cape Girardeau MO
$96 nightly
The price is $109 total per night
$109 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
30.33 mi from city center
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Isle Casino Cape Girardeau.
Parking included
Free WiFi

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
$84 nightly
The price is $91 total per night
$91 total
Jan 7 - Jan 8, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
32.93 mi from city center
With a stay at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau in Jackson, you'll be in the business district, within a 15-minute drive of Mississippi River and Cape Girardeau Conservation Nature Center.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Sikeston hotels essential information
Accommodation | 285 hotels |
|---|---|
Lowest Price | $63 |
Highest Price | $114 |
Popular hotels | Hampton Inn Sikeston, Drury Inn & Suites Sikeston, MO, Best Western Plus Sikeston, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67), Pear Tree Inn Sikeston, Days Inn and Suites by Wyndham Sikeston, Fairfield Inn & Suites by Marriott Sikeston, Super 8 by Wyndham Sikeston/Miner Area, Holiday Inn Express & Suites Sikeston Southwest by IHG, Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau |
Most Recent Sikeston Hotel Reviews

The Riverview
5 out of 5
Posted 3 days ago
CheapTickets Verified Review
"Didn’t eat breakfast "
A verified traveler stayed at The Riverview
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