Cheap Vacations in Port Isabel

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Port Isabel vacations

Price found within the past 48 hours. Click for updated prices.
The Pompano House in Port Isabel

The Pompano House in Port Isabel

2 out of 5
Price was $848, price is now $736 per person
$736
per person
Feb 3 - Feb 7
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Brownsville (BRO)

4-night Port Isabel vacations

Price found within the past 48 hours. Click for updated prices.
The Pompano House in Port Isabel

The Pompano House in Port Isabel

2 out of 5
Price was $848, price is now $736 per person
$736
per person
Feb 3 - Feb 7
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Brownsville (BRO)

Flight deals to Port Isabel

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Mon, Jan 5 - Wed, Jan 7
IAH
Houston
HRL
Harlingen
$184 Roundtrip, found 3 days ago
$184
Roundtrip
found 3 days ago
Select United flight, departing Mon, Jan 5 from Houston to Harlingen, returning Wed, Jan 7, priced at $184 found 3 days ago
Tue, Feb 3 - Fri, Feb 6
MSP
Minneapolis
HRL
Harlingen
$197 Roundtrip, found 2 days ago
$197
Roundtrip
found 2 days ago
Select Sun Country Airlines flight, departing Tue, Feb 3 from Minneapolis to Harlingen, returning Fri, Feb 6, priced at $197 found 2 days ago
Thu, Dec 18 - Wed, Dec 24
AUS
Austin
BRO
Brownsville
$208 Roundtrip, found 3 days ago
$208
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Thu, Dec 18 from Austin to Brownsville, returning Wed, Dec 24, priced at $208 found 3 days ago

Top rated hotels for your Port Isabel vacation

Port Isla Inn

Port Isla Inn

2 out of 5
200 2nd St Port Isabel TX
1.03 mi from city center
$65 nightly
The price is $75 total per night
$75 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
With a stay at Port Isla Inn, you'll be centrally located in Port Isabel, within a 10-minute drive of Beach Park at Isla Blanca and South Padre Island Beach.
Pool
Parking included
Casa Rosa Inn

Casa Rosa Inn

2.5 out of 5
761 W. Highway 100 Port Isabel TX
0.56 mi from city center
Get rates
With a stay at Casa Rosa Inn, you'll be centrally located in Port Isabel, within a 15-minute drive of Beach Park at Isla Blanca and South Padre Island Beach.
Pool
Pet friendly
Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island

4 out of 5
310 Padre Blvd South Padre Island TX
Free Cancellation
Reserve now, pay when you stay
2.86 mi from city center
$66 nightly
The price is $77 total per night
$77 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
When you stay at Margaritaville Beach Resort South Padre Island in South Padre Island, you'll be on the beach, a 2-minute drive from Beach Park at Isla Blanca and 10 minutes from South Padre Island Beach.
Pool
Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings with Flight + Hotel made on CheapTickets.com from 2019-04-01 - 2020-03-31 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.