Compare Cheap Hartsville Independent
Secret Bargains - Save an extra 10% or more on select hotels
Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Independent in Hartsville

Fairfield Inn by Marriott Hartsville
200 S 4th St Hartsville SC
$101 nightly
The price is $113 total per night
$113 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.15 mi from city center
A stay at Fairfield Inn by Marriott Hartsville places you in the heart of Hartsville, within a 5-minute walk of Coker College and Hartsville Museum.
Pool
Breakfast included

Hampton Inn & Suites Hartsville
203 East Carolina Ave. Hartsville SC
$135 nightly
The price is $151 total per night
$151 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.17 mi from city center
A stay at Hampton Inn & Suites Hartsville places you in the heart of Hartsville, within a 5-minute walk of East Home Avenue Historic District and Coker College.
Pool
Breakfast included

Quality Inn
903 S 5th Street Hartsville SC
$63 nightly
The price is $71 total per night
$71 total
Dec 23 - Dec 24
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.13 mi from city center
With a stay at Quality Inn in Hartsville, you'll be within a 5-minute drive of Hartsville Museum and Center Theatre.
Pool
Breakfast included

The Landmark Inn
1301 South 4th Street Hartsville SC
$76 nightly
The price is $84 total per night
$84 total
Dec 8 - Dec 9
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.58 mi from city center
Located in Hartsville, The Landmark Inn is within a 5-minute drive of Hartsville Museum and Coker College.
Pool
Breakfast included

The Mantissa Hotel
130 East Carolina Ave Hartsville SC
$162 nightly
The price is $181 total per night
$181 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.08 mi from city center
A stay at The Mantissa Hotel places you in the heart of Hartsville, steps from Hartsville Museum and 3 minutes by foot from Center Theatre.
Breakfast included
Parking included

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Hartsville SC
5.69 mi from city center
Located in Hartsville, Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi is within a 15-minute drive of Segars-McKinnon Heritage Preserve and Kalmia Gardens.
Kitchen
Pet friendly

Quiet lakefront condo with the best views on Prestwood lake.
Hartsville SC
0.97 mi from city center
Located in Hartsville, this condo is within a 5-minute drive of Lawton Park and Center Theatre.
Kitchen
Washer

Cozy Blue Cottage 2BR/1BA
Hartsville SC
1.13 mi from city center
Located in Hartsville, this cottage is within a 5-minute drive of Hartsville Memorial Library and Hartsville Museum.
Kitchen
Washer

Lakeside Living
Hartsville SC
5.7 mi from city center
Located in Hartsville, Lakeside Living is on the waterfront, within a 15-minute drive of Segars-McKinnon Heritage Preserve and Kalmia Gardens.
Hot Tub
Kitchen

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
$62 nightly
The price is $70 total per night
$70 total
Dec 8 - Dec 9
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.32 mi from city center
When you stay at Howard Johnson by Wyndham Florence in Florence, you'll be near the airport and within a 5-minute drive of Dr. Eddie Floyd Tennis Center.
Breakfast included
Parking included

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
$94 nightly
The price is $105 total per night
$105 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.35 mi from city center
When you stay at Park Inn by Radisson Florence, SC in Florence, you'll be near the airport and within a 5-minute drive of Dr. Eddie Floyd Tennis Center.
Breakfast included
Pet friendly

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
$100 nightly
The price is $112 total per night
$112 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.96 mi from city center
Located in Florence, Comfort Inn & Suites Florence Center Area is within a 5-minute drive of Florence Civic Center and Magnolia Mall.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Often, one of the most difficult things about booking a hotel is finding the best time to go. The cost of staying in hotels in could vary significantly, depending on the time of the year chosen. If you would like to figure out the most suitable time to take a trip then using CheapTickets could be the best option for you. We will be able to provide information on hotels in to ensure that you get the best deal possible. So if you are looking for a booking website that will streamline the process and offer good prices, then log in and get booking.
Hartsville hotels essential information
Accommodation | 173 hotels |
|---|---|
Lowest Price | $70 |
Highest Price | $181 |
Popular hotels | Fairfield Inn by Marriott Hartsville, Hampton Inn & Suites Hartsville, Quality Inn, The Landmark Inn, The Mantissa Hotel, Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi, Quiet lakefront condo with the best views on Prestwood lake., Cozy Blue Cottage 2BR/1BA, Lakeside Living, Howard Johnson by Wyndham Florence, Park Inn by Radisson Florence, SC, Comfort Inn & Suites Florence Center Area |
Most Recent Hartsville Hotel Reviews

The Mantissa Hotel
5 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Excellent staff and in the heart of a beautiful downtown."
A verified traveler stayed at The Mantissa Hotel
Types of Hotels
Top 20 Hartsville Hotels
Hotels Near Hartsville
Top Hotel Brands
Hotels By Star Rating
Cities near Hartsville
More to Explore in Hartsville
Top Picks
Hotels
- Hotels in Anderson
- Hotels in North Charleston
- Hotels in Sullivan's Island
- Hotels in Clemson
- Hotels in Mount Pleasant
- Hotels in Summerville
- Hotels in Surfside Beach
- Hotels in Charleston
- Hotels in Myrtle Beach
- Hotels in Greenville
- Hotels in Pawleys Island
- Hotels in Columbia
- Hotels in Daufuskie Island
- Hotels in Kiawah Island
- Hotels in Folly Beach
- 4 Star Hotels in Myrtle Beach
- Hotels in North Myrtle Beach
Flights





