Compare Cheap Hotels Near Florence (FLO) Airport

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Cheap Florence Regional Hotels

Hyatt Place Florence Downtown

100 East Evans Street Florence Florence SC

$100 nightly

$112 total

Jan 5 - Jan 6, 2026

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

2.15 mi from Florence Regional

A stay at Hyatt Place Florence Downtown places you in the heart of Florence, within a 10-minute walk of Pee Dee Mental Health Center and Drs Bruce and Lee Foundation Library.

Pool

Breakfast included

Hotel Florence, Tapestry Collection by Hilton

126 W Evans St Florence SC

$130 nightly

$146 total

Dec 28 - Dec 29

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

2.22 mi from Florence Regional

A stay at Hotel Florence, Tapestry Collection by Hilton places you in the heart of Florence, steps from Pee Dee Mental Health Center and 6 minutes by foot from Mcleod Regional Medical Center.

Spa

Parking included

Walking distance from one of South Carolina's top Medical centers.

Florence SC

$208 nightly

$233 total

Dec 21 - Dec 22

Total with taxes and fees

2.3 mi from Florence Regional

With a stay at this vacation home in Florence, you'll be within a 5-minute drive of Old Greenwood Athletic Park and Greenwood Baseball Park and Playground.

Kitchen

Washer

Rodeway Inn Florence Downtown

415 S. IRBY ST Florence SC

2.27 mi from Florence Regional

With a stay at Rodeway Inn Florence Downtown in Florence, you'll be a 4-minute walk from Drs Bruce and Lee Foundation Library and 12 minutes by foot from Pee Dee Mental Health Center.

Pet friendly

Free WiFi

Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees

Florence SC

2.27 mi from Florence Regional

Located in Florence, this vacation home is within a 10-minute drive of Florence National Cemetery and Old Greenwood Athletic Park.

Kitchen

Washer

Perfect Get-Away In The Heart Of Downtown Florence

Florence SC

2.41 mi from Florence Regional

With a stay at this vacation home in Florence, you'll be within a 5-minute drive of Pee Dee Mental Health Center and War Between the States Museum.

Washer

Dryer

Come Stay A While

Florence SC

2.42 mi from Florence Regional

With a stay at this cottage in Florence, you'll be within a 10-minute walk of Drs Bruce and Lee Foundation Library and Florence Museum.

Washer

Dryer

Hickory Haven 3Br Elegant Downtown Hidden Gem

Florence SC

2.59 mi from Florence Regional

With a stay at this vacation home in Florence, you'll be within a 10-minute walk of Florence Museum and Drs Bruce and Lee Foundation Library.

Kitchen

Washer

Cozy Retreat in Florence, SC

Florence SC

2.84 mi from Florence Regional

With a stay at this vacation home in Florence, you'll be within a 10-minute drive of Francis Marion University and Eastern Carolina Agricultural Fairgrounds.

Washer

Dryer

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC

$62 nightly

$70 total

Dec 21 - Dec 22

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

4.99 mi from Florence Regional

When you stay at Howard Johnson by Wyndham Florence in Florence, you'll be near the airport and within a 5-minute drive of Dr. Eddie Floyd Tennis Center.

Breakfast included

Parking included

Tasteful and peaceful unit near downtown

Florence SC

2.93 mi from Florence Regional

With a stay at this apartment in Florence, you'll be a 2-minute walk from War Between the States Museum and 15 minutes by foot from Florence Museum.

Kitchen

Washer

Pineapple House: Historic. Southern Charm. Walk Downtown.

Florence SC

3.01 mi from Florence Regional

A stay at this vacation home places you in the heart of Florence, within a 15-minute walk of War Between the States Museum and Florence Museum.

Kitchen

Washer

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Florence Regional hotels essential information

Accommodation	118 hotels
Lowest Price	$70
Highest Price	$233
Popular hotels	Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton, Walking distance from one of South Carolina's top Medical centers., Rodeway Inn Florence Downtown, Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees, Perfect Get-Away In The Heart Of Downtown Florence, Come Stay A While, Hickory Haven 3Br Elegant Downtown Hidden Gem, Cozy Retreat in Florence, SC, Howard Johnson by Wyndham Florence, Tasteful and peaceful unit near downtown, Pineapple House: Historic. Southern Charm. Walk Downtown.

Most Recent Florence Regional Hotel Reviews

Hyatt Place Florence Downtown

5 out of 5

Posted 4 days ago

CheapTickets Verified Review

"I wish Hyatt Place would upgrade the scramble egg on the menu. The powdered eggs are not very good. It's not the staff's fault. I'm sure it is a corporate decision. Step up the breakfast menu."

A verified traveler stayed at Hyatt Place Florence Downtown