See all 256 hotels in Orangeburg
- Tru by Hilton Orangeburg
- Travelodge by Wyndham Orangeburg
- SpringHill Suites by Marriott Orangeburg
- Fairfield Inn by Marriott Orangeburg
- Comfort Inn & Suites Orangeburg
- Baymont by Wyndham Orangeburg North
- Holiday Inn Express & Suites Orangeburg by IHG
- Hampton Inn & Suites Orangeburg
- Super 8 by Wyndham, Orangeburg
- Quality Inn & Suites Orangeburg
- Sleep Inn Orangeburg
- Days Inn by Wyndham Orangeburg South
- Southern Lodge & Suites
- Crown Inn By Oyo Orangeburg Hwy 301
- Southern Lodge 601
- American INN of Orangeburg
- Tru By Hilton Santee
- Baymont by Wyndham Santee
- Hampton Inn Santee-I-95
- Fairfield Inn & Suites by Marriott Santee
- Best Western Plus Santee Inn
- Holiday Inn Santee by IHG
- Peach Tree Inn
- Comfort Inn & Suites Santee
- Days Inn by Wyndham St George
- Travelodge by Wyndham Santee
- Quality Inn & Suites Santee I-95
- Budget Inn By Belvilla St George I-95
- Ramada by Wyndham Santee I-95
- Motel 6 Saint George, SC – I-95
- Red Roof Inn St George, SC
- Econo Lodge St. George
- Red Roof Inn Santee
- Waterfront Condo on Lake Marion
- Econo Lodge Santee
- Relax Inn
- Quality Inn St George I-95
- Americas Best Value Inn St. George, SC
- Lake Marion 2Bed/2Bath Deluxe!
- Lake Marion 3Bed/3Bath Deluxe!
- AIKEN HISTORIC FARMHOUSE w Stables, Turnout 20 min to TOWN.