Compare Cheap 4 Star Hotels

A stay at Quality Inn & Suites Hannibal West places you in the heart of Hannibal, a 3-minute drive from Hannibal Regional Hospital and 7 minutes from Molly Brown Museum and Home.

With a stay at Stoney Creek Inn Quincy in Quincy, you'll be in the business district, within a 10-minute drive of Mississippi River and Quincy Mall.

When you stay at Best Western On The River in Hannibal, you'll be in the historical district, within a 5-minute walk of Mississippi River and Jim's Journey: The Huck Finn Freedom Center.

With a stay at Comfort Inn & Suites - Hannibal, you'll be centrally located in Hannibal, within a 15-minute drive of Mississippi River and Sodalis Nature Preserve.

When you stay at Heritage Hotel Quincy in Quincy, you'll be in the business district, within a 10-minute walk of Mississippi River and Oakley Lindsay Center.

With a stay at Oak Hill Inn & Suites in Canton, you'll be within a 5-minute drive of Mississippi River and Golden Age Toys.

With a stay at AmericInn by Wyndham Quincy in Quincy, you'll be in a shopping district, within a 10-minute drive of Mississippi River and Quincy Mall.

With a stay at Baymont by Wyndham Hannibal, you'll be centrally located in Hannibal, within a 15-minute drive of Mississippi River and Sodalis Nature Preserve.

With a stay at Motel 6 Hannibal, MO in Hannibal, you'll be within a 10-minute drive of Mississippi River and Indian Mounds Park.

A stay at Sleep Inn & Suites Hannibal West places you in the heart of Hannibal, within a 5-minute drive of Hospital Park and Hannibal Regional Hospital.

With a stay at Microtel Inn & Suites by Wyndham Quincy Downtown/River Area in Quincy, you'll be on the riverwalk, just steps from Oakley Lindsay Center and a 4-minute drive from Quincy University.

With a stay at Cannon Dam Cabins in Perry, you'll be 0.9 mi (1.4 km) from Mark Twain Lake and 16.7 mi (26.9 km) from Mark Twain State Park.