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Lowest round trip fares by airline from Orlando and Hyannis

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Cheap flights from Orlando to Hyannis

Cheap flights from Orlando to Hyannis

Are you ready to book your flight, but feeling nervous about paying too much if the price drops? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus a $50 CheapCash bonus, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a Hyannis Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Hyannis vacation that you can't get when you book flights and hotel separately.

Relax in Hyannis With Confidence and Convenience

Going cheap doesn't mean giving up great service. Our agents are available 24/7 to help you find the right cheap flights and hotel, and to answer questions about your trip.

Need to grab a cheap travel deal while you're on the go? Download our mobile app, where you can search and book just like you would on your home computer. Stay in-the-know on great rates on flights from Orlando to Hyannis by signing up for exclusive email deals.

Hotels in Hyannis

See all 115 Properties in Hyannis
Cape Codder Resort and Spa

Cape Codder Resort and Spa

1225 Iyannough Rd, Hyannis, MA
    3.0 out of 5.0
     
     
    3.5 out of 5 (2 reviews)

    This family-friendly Hyannis resort is located near the airport, within 2 mi (3 km) of Cape Codder Water Park and Hyannis Golf Course. Hyannis Harbor is 2.7 ...

    Cape Codder Resort and Spa$139

    Cape Codder Resort and Spa$139
    Hyannis Harbor Hotel

    Hyannis Harbor Hotel

    213 Ocean St, Hyannis, MA
      3.5 out of 5.0
       
       
      3.7 out of 5 (3 reviews)

      This family-friendly Hyannis hotel is located on the waterfront, within 1 mi (2 km) of John F. Kennedy Hyannis Museum and Kalmus Beach. Cape Cod Melody Tent ...

      Hyannis Harbor Hotel$119

      Hyannis Harbor Hotel$119
      Hyannis Travel Inn

      Hyannis Travel Inn

      18 North St, Hyannis, MA
        2.0 out of 5.0
         
         
        4.5 out of 5 (2 reviews)

        Located in the heart of Hyannis, this hotel is within a 15-minute walk of John F. Kennedy Hyannis Museum and Hyannis Harbor. Cape Codder Water Park is 2.4 mi ...

        Hyannis Travel Inn$80

        Hyannis Travel Inn$80
        Hyannis Inn

        Hyannis Inn

        473 MAIN ST, Hyannis, MA
          2.0 out of 5.0
           
           
          5.0 out of 5 (2 reviews)

          Located in the heart of Hyannis, this motel is within a 15-minute walk of St. Francis Xavier Church and Hyannis Harbor. Cape Codder Water Park is 2.1 mi (3.4 ...

          Hyannis Inn$100

          Hyannis Inn$100
          Best Western Cape Cod Hotel

          Best Western Cape Cod Hotel

          1470 Iyannough Rd. Rt 132, Hyannis, MA
            2.5 out of 5.0
             
             
            4.0 out of 5 (1 reviews)

            This family-friendly hotel is located in the city center, within 1 mi (2 km) of Hyannis Golf Course and Cape Codder Water Park. Cape Cod Carousel and Wild Animal ...

            Best Western Cape Cod Hotel$105

            Best Western Cape Cod Hotel$105
            Resort & Conference Center at Hyannis

            Resort & Conference Center at Hyannis

            35 Scudder Avenue, Hyannis, MA
              3.5 out of 5.0
               
               
              2.0 out of 5 (3 reviews)

              Located in the heart of Hyannis, this family-friendly resort is steps from Twin Brooks Golf Course and Cape Cod Melody Tent. Hyannis Harbor and Cape Codder Water ...

              Resort & Conference Center at Hyannis$110

              Resort & Conference Center at Hyannis$110
              Americas Best Value Inn & Suites Hyannis Cape Cod

              Americas Best Value Inn & Suites Hyannis Cape Cod

              206 Main St, Hyannis, MA
                2.0 out of 5.0
                 
                 
                3.7 out of 5 (23 reviews)

                Located in the heart of Hyannis, this hotel is within a 10-minute walk of Cape Cod Maritime Museum and Hyannis Harbor. Cape Codder Water Park is 2.5 mi (4 km) ...

                Americas Best Value Inn & Suites Hyannis Cape Cod$69

                Americas Best Value Inn & Suites Hyannis Cape Cod$69
                Heritage House Hotel

                Heritage House Hotel

                259 Main Street, Hyannis, MA
                  2.5 out of 5.0
                   
                   
                  4.4 out of 5 (5 reviews)

                  Located in the heart of Hyannis, this hotel is within a 10-minute walk of John F. Kennedy Hyannis Museum and Hyannis Harbor. Cape Cod Carousel and St. Francis ...

                  Heritage House Hotel$89

                  Heritage House Hotel$89
                  Holiday Inn Hyannis

                  Holiday Inn Hyannis

                  1127 Iyannough Rd, Hyannis, MA
                    3.0 out of 5.0
                     
                     
                    4.5 out of 5 (2 reviews)

                    Located in the heart of Hyannis, this hotel is within 3 mi (5 km) of John F. Kennedy Hyannis Museum, Cape Cod Melody Tent, and St. Francis Xavier Church. Hyannis ...

                    Holiday Inn Hyannis$143

                    Holiday Inn Hyannis$143
                    Hyannis Holiday Motel

                    Hyannis Holiday Motel

                    131 Ocean St, Hyannis, MA
                      2.0 out of 5.0
                       
                       
                      3.0 out of 5 (4 reviews)

                      Situated near the beach, this motel is within a 10-minute walk of Cape Cod Maritime Museum and Hyannis Harbor. Cape Codder Water Park is 2.6 mi (4.2 km) away. ...

                      Hyannis Holiday Motel$93

                      Hyannis Holiday Motel$93
                      Map

                      *Savings based on all holiday package bookings with Flight + Hotel on CheapTickets.com from January through December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

                      *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.