Compare Luxury Hotels in Syracuse

Secret Bargains - Save an extra 10% or more on select Luxury Hotels

Start date: Check-in selected.
To Date
End date: Check-out

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Featured Syracuse Luxury Hotels

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

5 out of 5
Passeggio Adorno 10/12 Syracuse SR
With a stay at Grand Hotel Des Ètrangers - The Leading Hotels of the World in Syracuse (Ortigia), you'll be steps from Tropical Aquarium of Syracuse and Fonte Aretusa.
Pool
Breakfast included
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

5 out of 5
Viale Mazzini, 12 Syracuse SR
$214 nightly
The price is $247 total per night
$247 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Grand Hotel Ortigia Siracusa places you in the heart of Syracuse, steps from Ionian Sea and Porta Marina.
Spa
Free WiFi
Minareto

Minareto

5 out of 5
Via del Faro Massolivieri 26 Syracuse SR
When you a stay at Minareto in Syracuse, you'll be near the bay, just steps from Ionian Sea and Spiaggia del Minareto.
Pool
Breakfast included
Eureka Palace Hotel Spa Resort

Eureka Palace Hotel Spa Resort

4 out of 5
Strada Spinagallo 50 Syracuse SR
Free Cancellation
Reserve now, pay when you stay
Located in Syracuse, Eureka Palace Hotel Spa Resort is in the business district, within a 10-minute drive of Pineta del Gelsomineto Beach and Ionian Sea.
Pool
Hot Tub
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

4 out of 5
Via Vittorio Veneto 93 Syracuse SR
Free Cancellation
Reserve now, pay when you stay
A stay at Algila' Ortigia Charme Hotel places you in the heart of Syracuse, steps from Ionian Sea and Lungomare di Ortigia.
Breakfast included
Free WiFi
Hotel Livingston Siracusa

Hotel Livingston Siracusa

4 out of 5
Via Nizza, 17 Syracuse SR
A stay at Hotel Livingston Siracusa places you in the heart of Syracuse, steps from Lungomare di Ortigia and Ionian Sea.
Breakfast included
Free WiFi
Hotel Parco delle Fontane

Hotel Parco delle Fontane

4 out of 5
Viale Scala Greca, 325 Syracuse SR
$108 nightly
The price is $124 total per night
$124 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hotel Parco delle Fontane in Syracuse (Tiche), you'll be a 3-minute walk from Doggy Park and within a 5-minute drive of Ionian Sea.
Pool
Breakfast included
Grande Albergo Alfeo

Grande Albergo Alfeo

4 out of 5
Via Nino Bixio 5 Syracuse SR
Free Cancellation
Reserve now, pay when you stay
A stay at Grande Albergo Alfeo places you in the heart of Syracuse, within a 5-minute walk of Santa Lucia Bridge and Syracuse Forum Ruins.
Breakfast included
Pet friendly
Charme Hotel Henry's House

Charme Hotel Henry's House

4 out of 5
Via del Castello Maniace n. 68 Syracuse SR
$281 nightly
The price is $321 total per night
$321 total
Dec 27 - Dec 28
Total with taxes and fees
A stay at Charme Hotel Henry's House places you in the heart of Syracuse, steps from Lungomare di Ortigia and Ionian Sea.
Breakfast included
Free WiFi
Palazzo Artemide - VRetreats

Palazzo Artemide - VRetreats

4 out of 5
Via Roma 66 Syracuse SR
$257 nightly
The price is $295 total per night
$295 total
Dec 11 - Dec 12
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Palazzo Artemide - VRetreats, SLH Collection, you'll be centrally located in Syracuse, steps from Cathedral of Syracuse and Piazza del Duomo.
Pet friendly
Free WiFi
L'Approdo delle Sirene

L'Approdo delle Sirene

3 out of 5
Riva Giuseppe Garibaldi 15 Syracuse SR
Located in Syracuse (Ortigia), L'Approdo delle Sirene is a 3-minute walk from Temple of Apollo and 7 minutes by foot from Cathedral of Syracuse.
Free WiFi
Air conditioning
Alla Giudecca

Alla Giudecca

3 out of 5
Via Alagona 52, Ortigia Syracuse SR
Free Cancellation
Reserve now, pay when you stay
With a stay at Alla Giudecca in Syracuse (Ortigia), you'll be steps from Jewish Bath and Museum of Cinema.
Kitchen
Free WiFi
Don't see what you're looking for?
See all available properties in Syracuse
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Often, one of the most difficult things about booking a hotel is finding the best time to go. The cost of staying in hotels in could vary significantly, depending on the time of the year chosen. If you would like to figure out the most suitable time to take a trip then using CheapTickets could be the best option for you. We will be able to provide information on hotels in to ensure that you get the best deal possible. So if you are looking for a booking website that will streamline the process and offer good prices, then log in and get booking.

Syracuse hotels essential information

Accommodation
2,170 hotels
Lowest Price
$124
Highest Price
$321
Popular hotels
Grand Hotel Des Ètrangers - The Leading Hotels of the World, Grand Hotel Ortigia Siracusa, Minareto, Eureka Palace Hotel Spa Resort, Algila' Ortigia Charme Hotel, Hotel Livingston Siracusa, Hotel Parco delle Fontane, Grande Albergo Alfeo, Charme Hotel Henry's House, Palazzo Artemide - VRetreats, L'Approdo delle Sirene, Alla Giudecca

Most Recent Syracuse Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

5 out of 5
Posted 8 days ago
CheapTickets Verified Review
"Great location. Great service. Enjoy Ortigia!"
A verified traveler stayed at Algila' Ortigia Charme Hotel
Algila' Ortigia Charme Hotel

Types of Hotels

Top 20 Syracuse Hotels

Top Hotel Brands

Hotels By Star Rating

Cities near Syracuse