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Hampton Inn & Suites St. Louis/South I-55

Property class: 2.5

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Photo gallery for Hampton Inn & Suites St. Louis/South I-55

A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.
A modern kitchen with a sink, dishwasher, and microwave. There is a large mirror above the sink and a countertop with various items. The room has a neutral color scheme and a view of a living area with a couch and a TV.
Pool
A gym with treadmills, exercise bikes, and a mirror.
A snack display area with various packaged snacks and a refrigerated section.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
The current price is $126
$110 nightly
$126 total
Total with taxes and fees
Oct 31 - Nov 1

Explore the area

View in a map
4200 Midamerica Lane, St. Louis, MO, 63129
  • Place, Gateway Arch
    ‪17 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Place, St. Louis Zoo
    ‪23 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪29 min drive‬

Room options

View all photos for Room, 2 Queen Beds

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room, 2 Queen Beds

9.8 out of 10
Exceptional
(41 reviews)
  • 460 sq ft
  • Sleeps 4
  • 2 Queen Beds
  • Free wired internet

View all photos for Room, 1 King Bed

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room, 1 King Bed

9.8 out of 10
Exceptional
(19 reviews)
  • 460 sq ft
  • Sleeps 2
  • 1 King Bed
  • Free wired internet

View all photos for Studio Suite, 1 King Bed with Sofa bed, Microwave

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Studio Suite, 1 King Bed with Sofa bed, Microwave

9.2 out of 10
Wonderful
(5 reviews)
  • 460 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free wired internet

View all photos for Studio Suite, 1 King Bed with Sofa bed, Jetted Tub

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Studio Suite, 1 King Bed with Sofa bed, Jetted Tub

10.0 out of 10
Exceptional
(3 reviews)
  • 460 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free wired internet

View all photos for Room, 2 Queen Beds, Accessible, Microwave (Mobility and Hearing)

A hotel room with a bed, desk, chair, television, and a minibar.

Room, 2 Queen Beds, Accessible, Microwave (Mobility and Hearing)

9.6 out of 10
Exceptional
(29 reviews)
  • 460 sq ft
  • Sleeps 4
  • 2 Queen Beds
  • Free wired internet

View all photos for Room, 1 King Bed, Accessible, Microwave (Mobility and Hearing)

A hotel room with a large bed, two bedside lamps, a nightstand with a phone, and a door to another room.

Room, 1 King Bed, Accessible, Microwave (Mobility and Hearing)

9.8 out of 10
Exceptional
(23 reviews)
  • 460 sq ft
  • Sleeps 2
  • 1 King Bed
  • Free wired internet

View all photos for Studio, 1 King Bed with Sofa bed, Accessible, Microwave (Mobility and Hearing)

A hotel room with a bed, a desk with a telephone, a chair, a sofa, a lamp, and a painting on the wall.

Studio, 1 King Bed with Sofa bed, Accessible, Microwave (Mobility and Hearing)

8.0 out of 10
Very good
(6 reviews)
  • 460 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free wired internet

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About the neighborhood

St. Louis

With a stay at Hampton Inn & Suites St. Louis/South I-55 in St. Louis, you'll be within a 10-minute drive of Mississippi River and Barnes Jewish South Campus. .This hotel is 13.3 mi (21.4 km) from St. Louis Zoo and 11.3 mi (18.1 km) from Missouri Botanical Garden.

What's nearby

  • Busch Stadium - 16 min drive - 17.6 miles
  • Gateway Arch - 17 min drive - 18.0 miles
  • Enterprise Center - 17 min drive - 18.2 miles
  • St. Louis Union Station - 18 min drive - 17.6 miles
  • St. Louis Zoo - 23 min drive - 22.2 miles

Getting around

  • Kirkwood Station - 14 min drive
  • St. Louis Lambert Intl. Airport (STL) - 31 min drive

Restaurants

  • ‪McDonald's - ‬3 min drive
  • ‪Burger King - ‬10 min walk
  • ‪Hardee's / Red Burrito - ‬10 min walk
  • ‪Subway - ‬3 min drive
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive

About this property

Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55 offers 92 accommodations with safes and coffee/tea makers. 37-inch LCD televisions come with cable channels and pay movies. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include complimentary toiletries and hair dryers.

This St. Louis hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include complimentary weekday newspapers and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool and a fitness center.

Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision.

Make yourself at home in one of the 92 guestrooms featuring refrigerators and LCD televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms have complimentary toiletries and hair dryers. Conveniences include safes and complimentary weekday newspapers, as well as phones with free local calls.
Enjoy recreational amenities such as an indoor pool and a fitness center. This hotel also features complimentary wireless internet access, a fireplace in the lobby, and a banquet hall.
Grab a bite from the grocery/convenience store serving guests of Hampton Inn & Suites St. Louis/South I-55. A complimentary buffet breakfast is served daily from 6:00 AM to 10:00 AM.
Featured amenities include complimentary wired internet access, a business center, and express check-in. Planning an event in St. Louis? This hotel has 753 square feet (70 square meters) of space consisting of conference space and a meeting room. Free self parking is available onsite.
A complimentary buffet breakfast is served each morning between 6:00 AM and 10:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Hot tub
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business center
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Contactless check-in available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 75 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total pets
Pets cannot be left unattended

Children and extra beds

Children are welcome
Free cribs are available on request at the property

Property payment types

  • American Express
  • Discover
  • Mastercard
  • Visa

Important information

Optional extras

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Hampton Inn I-55
Hampton Inn I-55 St.Louis
Hampton Inn South St.Louis
Hampton Inn St.Louis I-55
Hampton Inn St.Louis South
Hampton Inn St.Louis South I-55
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 St. Louis
St.Louis South
Hampton Inn Suites St.Louis South at I 55

Hampton Inn & Suites St. Louis/South I-55 Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 814 out of 1001 reviews
Rating 8 - Good. 134 out of 1001 reviews
Rating 6 - Okay. 27 out of 1001 reviews
Rating 4 - Poor. 5 out of 1001 reviews
Rating 2 - Terrible. 21 out of 1001 reviews

9.6/10

Cleanliness

9.8/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great stay and staff was very helpful!
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing hotel and staff
Stayed 8 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel is very beautiful and modern. Our room was excellent! The beds are very comfortable, but most importantly the front desk staff are some of the most amazing and helpful people! And I would love to give a shout out to Priscilla, who was just very accommodating and very nice!! Bonus : the food is good !!
Stayed 4 nights in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was friendly, breakfast was delicious. I really enjoyed my stay
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, polite staff, great location
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean and comfortable
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Every thing was great and will be back soon
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great shower, place was tip top
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Parking felt safe , nice staff
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I had a great stay. Clean rooms and friendly staff
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room and good breakfast. We love stay in this hotel.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Breakfast was excellent. Clean fresh room. Nice staff. Lots of parking. Excellent stay!!
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff friendly, parking lot security, clean and smells clean when you enter room.
Stayed 1 night in Apr 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Parking was great, very close to all highways, staff super friendly, and room was great. Food not the best to me but I would stay here again.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location. Clean.
Stayed 1 night in Apr 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Parking was safe. Easy location
Stayed 3 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Kudos to both the housecleaning staff for such a clean room & the breakfast attendants that were supervising the breakfast. They were all super friendly & helpful! Bed was comfy, loved the shower, breakfast was good, & so very happy that y'all allow dogs!!! I wish the pet fee was a little cheaper, though. We have stayed there before & will definitely stay again!
Stayed 3 nights in May 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We stayed one night on our way back from Tulsa OK to Indianapolis. We were traveling with a small dog and needed space to walk her. We drove to area restaurants and stores and found them easily accessible without using the Interstate. The hotel was quiet and well kept, and the staff took care of our rather minor needs.
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Room was clean and comfortable Staff professional friendly and helpful Breakfast was great! Several choices.
Stayed 5 nights in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The front desk attendant was very helpful and welcoming. I was impressed wit the cleanliness of our room and the hot breakfast options. Would definitely stay there again!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really nice rooms and staff , good breakfast!
Stayed 1 night in Sep 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very cl
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a great stay for us! Friendly desk and breakfast staff. Clean throughout the property! Very comfortable.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was clean. Staff was courteous. The breakfast was average for 3 star hotel.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

The room was excellent and so was the staff.
Stayed 1 night in Jan 2026