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Featured Spartanburg Business Hotels

Holiday Inn Spartanburg Northwest by IHG
160 Simuel Road Spartanburg SC
$85 nightly
The price is $94 total per night
$94 total
Dec 26 - Dec 27
Total with taxes and fees
Free Cancellation
A stay at Holiday Inn Spartanburg Northwest by IHG places you in the heart of Spartanburg, within a 5-minute drive of University of South Carolina Upstate and Spartanburg Regional Hospital.
Pool
Parking included

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
895 Spartan Blvd Spartanburg SC
$89 nightly
The price is $99 total per night
$99 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
With a stay at Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG in Spartanburg, you'll be within a 15-minute walk of Regal Spartan and WestGate Mall.
Pool
Breakfast included

Best Western Spartanburg Northwest
110 Mobile Dr Spartanburg SC
$84 nightly
The price is $93 total per night
$93 total
Dec 21 - Dec 22
Total with taxes and fees
With a stay at Best Western Spartanburg Northwest in Spartanburg, you'll be in the business district, just a 5-minute walk from North Town Center and 6 minutes by foot from Upper Chinquapin Preserve.
Pool
Breakfast included

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
161 Sha Ln Spartanburg SC
$97 nightly
The price is $108 total per night
$108 total
Dec 28 - Dec 29
Total with taxes and fees
Free Cancellation
Located in Spartanburg, Holiday Inn Express Hotel & Suites Spartanburg-North by IHG is within a 5-minute drive of Cleveland Preserve Farm and Plankowner Brewing Co..
Pool
Breakfast included

Comfort Suites At WestGate Mall
458 West Blackstock Road Spartanburg SC
$91 nightly
The price is $101 total per night
$101 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Comfort Suites At WestGate Mall places you in the heart of Spartanburg, within a 5-minute drive of WestGate Mall and Regal Spartan.
Pool
Breakfast included

Comfort Inn & Suites Spartanburg North
154 Candlenut Lane I-85 Exit 75 Spartanburg SC
$80 nightly
The price is $89 total per night
$89 total
Dec 16 - Dec 17
Total with taxes and fees
A stay at Comfort Inn & Suites Spartanburg North places you in the heart of Spartanburg, within a 5-minute drive of Plankowner Brewing Co. and The Shoppes at Rocky Branch.
Pool
Breakfast included

Quality Inn Spartanburg Northwest
6690 Pottery Rd Spartanburg SC
$61 nightly
The price is $68 total per night
$68 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Spartanburg, Quality Inn Spartanburg Northwest is within a 10-minute drive of University of South Carolina Upstate and WestGate Mall.
Breakfast included
Parking included

Spartanburg Marriott
299 North Church Street Spartanburg SC
$118 nightly
The price is $131 total per night
$131 total
Dec 23 - Dec 24
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Spartanburg Marriott places you in the heart of Spartanburg, steps from Speed Factory Indoor Karting and 4 minutes by foot from Spartanburg Memorial Auditorium.
Pool
Parking included

Residence Inn by Marriott Spartanburg
9011 Fairforest Rd Spartanburg SC
$83 nightly
The price is $92 total per night
$92 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Residence Inn by Marriott Spartanburg in Spartanburg, you'll be in the business district, within a 5-minute drive of North Towne Commons and North Town Center.
Pool
Breakfast included

Days Inn by Wyndham Spartanburg
115 Rogers Commerce Blvd Boiling Springs SC
$77 nightly
The price is $85 total per night
$85 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Boiling Springs, Days Inn by Wyndham Spartanburg is in a rural location, within a 5-minute drive of Plankowner Brewing Co. and The Shoppes at Rocky Branch.
Pool
Parking included

Best Western Plus Spartanburg
125 Sloane Garden Rd Spartanburg SC
$84 nightly
The price is $94 total per night
$94 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Best Western Plus Spartanburg in Spartanburg, you'll be steps from Plankowner Brewing Co. and a 3-minute drive from North Grove Medical Park.
Pool
Breakfast included

Days Inn by Wyndham Spartanburg Waccamaw
101 Outlet Rd Spartanburg SC
$57 nightly
The price is $63 total per night
$63 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Spartanburg, Days Inn by Wyndham Spartanburg Waccamaw is a 1-minute drive from Spartanburg Expo Center and 7 minutes from University of South Carolina Upstate.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Spartanburg hotels essential information
Accommodation | 1,075 hotels |
|---|---|
Lowest Price | $63 |
Highest Price | $131 |
Popular hotels | Holiday Inn Spartanburg Northwest by IHG, Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG, Best Western Spartanburg Northwest, Holiday Inn Express Hotel & Suites Spartanburg-North by IHG, Comfort Suites At WestGate Mall, Comfort Inn & Suites Spartanburg North, Quality Inn Spartanburg Northwest, Spartanburg Marriott, Residence Inn by Marriott Spartanburg, Days Inn by Wyndham Spartanburg, Best Western Plus Spartanburg, Days Inn by Wyndham Spartanburg Waccamaw |
Most Recent Spartanburg Hotel Reviews

Spartanburg Marriott
5 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Bed and pillows were amazing....
"
A verified traveler stayed at Spartanburg Marriott
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