Roxboro Vacation Rentals

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Vacation Rentals in Roxboro

Kerr/Buggs Island Lake waterfront home w/dock, just off main channel!

Clarksville VA

With a stay at this vacation home in Clarksville (Merifield Acres), you'll be within a 15-minute drive of John H. Kerr Reservoir and Merifield Wildlife Management Area.

Durham Retreat: Deck, Grill, Firepit, 10 mins from Duke & Downtown

Durham NC

With a stay at this vacation home in Durham, you'll be within a 10-minute drive of Duke University and Duke University Hospital.

Charming 3-bedroom house, in pleasant North Durham

Durham NC

$385 nightly

$437 total

Jan 6 - Jan 7, 2026

Total with taxes and fees

With a stay at this vacation home in Durham, you'll be within a 15-minute drive of Duke University and Duke University Hospital.

H2O-FRONT Chef’s_Kitchen Gig-WiFi DogsOK EV-Charger Alexa

Clarksville VA

With a stay at this vacation home in Clarksville (Merifield Acres), you'll be a 1-minute drive from John H. Kerr Reservoir and 10 minutes from Merifield Wildlife Management Area.

Urban Oasis w/ King Bed – 3 BR Near Duke & DT

Durham NC

With a stay at this vacation home in Durham, you'll be within a 10-minute drive of Duke University and Duke University Hospital.

Charming 4-bedroom 3-bath house on beautiful Hyco Lake with boat dock.

Semora NC

When you stay at this vacation home in Semora, you'll be within a 5-minute drive of Hyco Lake.

Cozy Ranch New Build 3 bed 2 bath

Durham NC

$358 nightly

$406 total

Dec 17 - Dec 18

Total with taxes and fees

With a stay at this vacation home in Durham, you'll be within a 10-minute drive of Duke University and Duke University Hospital.

Dog Friendly House Near Duke + Downtown + Airport

Durham NC

$285 nightly

$323 total

Dec 17 - Dec 18

Total with taxes and fees

With a stay at this vacation home in Durham, you'll be within a 10-minute drive of Duke University and Duke University Hospital.

WATERFRONT LOG HOME FOR FAMILY CHRISTMAS! HOT TUB/FIREPLACES/LARGE DECK/FIRE PIT

Clarksville VA

A stay at this vacation home places you in the heart of Clarksville, a 1-minute drive from John H. Kerr Reservoir and 9 minutes from Prestwould Plantation.

"Cottage On The Cove" Private Lakefront Paradise with Paddleboards & Kayaks

Roxboro NC

Located in Roxboro, this vacation home is on the waterfront, a 1-minute drive from Mayo Lake and 6 minutes from Mayo Park.

Parthenia 3BR@American Village - Private cul-de-sac home

Durham NC

$293 nightly

$333 total

Dec 17 - Dec 18

Total with taxes and fees

With a stay at this vacation home in Durham, you'll be within a 10-minute drive of Duke University and Duke University Hospital.

Private dock/beach on quiet cove - Lake house w/ king beds. Pet-friendly

Clarksville VA

Located in Clarksville, this vacation home is on the waterfront, within a 15-minute drive of John H. Kerr Reservoir and Prestwould Plantation.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.