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Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property

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Photo gallery for Residence Inn Durham McPherson/Duke University Medical Cntr

An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.
A hotel room with two beds, a desk, a TV, and a sofa.
A gym with treadmills, elliptical machines, a bench press, and a blue balance board.
A multi-story brick building with a modern entrance and a parking lot.
A spacious lobby with a reception desk, seating area, and a beverage kiosk.

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
The current price is $150
$132 nightly
$150 total
Total with taxes and fees
Aug 10 - Aug 11

Explore the area

View in a map
1108 West Main Street, Durham, NC, 27701
  • Place, Duke University
    ‪3 min walk‬
  • Place, Durham Convention Center
    ‪12 min walk‬
  • Place, Durham Performing Arts Center
    ‪16 min walk‬
  • Airport, Raleigh, NC (RDU-Raleigh - Durham Intl.)
    ‪19 min drive‬

Room options

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

8.8 out of 10
Excellent
(6 reviews)
  • 469 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed

9.0 out of 10
Wonderful
(37 reviews)
  • 480 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 Queen Bed with Sofa bed

A modern hotel room with a bed, a TV, a kitchenette, and a dining area.

Studio, 1 Queen Bed with Sofa bed

9.8 out of 10
Exceptional
(16 reviews)
  • 424 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Hearing Accessible)

A hotel room with a bed, a desk, a chair, and a TV.

Suite, 1 Bedroom (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

10.0 out of 10
Exceptional
(2 reviews)
  • 478 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

  • 479 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

  • 479 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

A hotel room with a bed, a desk, a chair, and a TV.

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

  • 426 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, Multiple Beds (Mobility Accessible, Tub)

A hotel room with two beds, a flat-screen TV mounted on the wall, a wooden headboard, and a window with sheer curtains.

Suite, Multiple Beds (Mobility Accessible, Tub)

8.0 out of 10
Very good
(3 reviews)
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

A hotel room with a bed, a desk, a chair, and a TV.

Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

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About the neighborhood

Durham

Located in Durham (Trinity Park), Residence Inn Durham McPherson/Duke University Medical Cntr is steps from Duke University and a 3-minute drive from Durham Performing Arts Center. .This hotel is 1.9 mi (3.1 km) from Duke University Hospital and 7.3 mi (11.7 km) from Research Triangle Park.

What's nearby

  • Brightleaf Square - 3 min walk - 0.2 miles
  • Duke University - 3 min walk - 0.2 miles
  • Durham Convention Center - 12 min walk - 0.7 miles
  • Durham Performing Arts Center - 16 min walk - 0.9 miles
  • Durham Bulls Athletic Park - 18 min walk - 1.0 mile

Getting around

  • Durham Station - 8 min walk
  • Raleigh-Durham International Airport (RDU) - 21 min drive

Restaurants

  • ‪The Federal - ‬3 min walk
  • ‪Atomic Clock Brewing Co - ‬11 min walk
  • ‪Grub Durham - ‬12 min walk
  • ‪The Can Opener - ‬7 min walk
  • ‪It's A Southern Thing - ‬7 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr offers 147 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas and include dining tables. 32-inch Smart televisions come with premium cable channels, pay movies, and Netflix. Accommodations at this 3-star hotel have kitchens with full-sized refrigerators/freezers, stovetops, microwaves, and cookware/dishes/utensils. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers.

This Durham hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and desk chairs, as well as phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include a 24-hour fitness center.

Children under 18 years old are not allowed in the swimming pool or fitness facility without adult supervision. Guests under 18 years old are not allowed in the fitness facility.

Make yourself at home in one of the 147 guestrooms, featuring kitchens with full-sized refrigerators/freezers and stovetops. 32-inch Smart televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Conveniences include safes and desks, as well as phones with free local calls.
Enjoy recreation amenities such as a 24-hour fitness center or take in the view from a terrace. This hotel also features complimentary wireless internet access, concierge services, and wedding services. Guests can catch a ride to nearby destinations on the complimentary area shuttle.
Grab a bite from the grocery/convenience store serving guests of Residence Inn Durham McPherson/Duke University Medical Cntr. A complimentary on-the-go breakfast is served daily from 7:00 AM to 9:00 AM.
Featured amenities include a business center, express check-in, and express check-out. Planning an event in Durham? This hotel has facilities measuring 2530 square feet (235 square meters), including conference space. Self parking (subject to charges) is available onsite.
A complimentary on-the-go breakfast is served each morning between 7:00 AM and 9:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free area shuttle
  • Self parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business center
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Hardwood flooring in room
  • Lever door handles
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Built in 2015
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Non-plastic coffee stirrers available
  • Renovated entire property - April 2024
  • Smoking not allowed
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Kitchen
  • Microwave
  • Stovetop

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)
Service animals are welcome, and are exempt from fees
2 total (up to 100 lbs per pet)
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Self parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 330 out of 487 reviews
Rating 8 - Good. 109 out of 487 reviews
Rating 6 - Okay. 29 out of 487 reviews
Rating 4 - Poor. 8 out of 487 reviews
Rating 2 - Terrible. 11 out of 487 reviews

9.4/10

Cleanliness

9.4/10

Staff & service

8.8/10

Amenities

9.2/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

RICHARD

Liked: Cleanliness, staff & service, property conditions & facilities
Great downtown location
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Anna F

Liked: Cleanliness, amenities, property conditions & facilities
Courteous staff, spotless rooms, comfortable bed and pillows.
Stayed 4 nights in Dec 2025
Verified

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was great - very friendly staff.
Stayed 2 nights in Sep 2025
Verified

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities
We love this hotel. The staff is excellent and the rooms are well designed and comfortable. The breakfast is delicious.
Stayed 10 nights in Dec 2025
Verified

10/10 Excellent

Syreeta

Liked: Cleanliness, staff & service, amenities
Rooms were spacious and spotless. Customer Service was phenomenal! Housekeeping were friendly and had no problems giving the extra items needed, including extra pillows.
Stayed 2 nights in Feb 2026
Verified

8/10 Good

Minor

Liked: Cleanliness, staff & service
An excellent place to stay!
Stayed 1 night in Feb 2025
Verified

10/10 Excellent

Tim

Liked: Cleanliness, staff & service, amenities
Great stay. The hotel breakfast left a little something to be desired but the room was clean, the staff was helpful. This was everything I expected.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Judy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location with some incredible Restaurants nearby
Stayed 3 nights in Oct 2024
Verified

6/10 Okay

Susan

Liked: Cleanliness, amenities, property conditions & facilities
Wi-Fi did not work and we were not told the procedure for paying for parking. Received a $20 ticket.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Derek

Liked: Cleanliness, staff & service, property conditions & facilities
Was very nice. The staff was very polite when we arrived.
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great and reasonably priced place to stay as a family in the center of Durham.
Stayed 1 night in Sep 2024
Verified

10/10 Excellent

Jackson

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice clean room,good breakfast and great staff.
Stayed 4 nights in Nov 2022
Verified

10/10 Excellent

Wendy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, friendly, great location.
Stayed 1 night in Sep 2024
Verified

10/10 Excellent

Christopher

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place!
Stayed 3 nights in Dec 2023
Verified

8/10 Good

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel for the price. Good location. Big rooms. Quiet. Easy parking. Could be a little cleaner.
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Jo Anne

Liked: Cleanliness, staff & service, property conditions & facilities
Great place
Stayed 2 nights in May 2024
Verified

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025
Verified

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025
Verified

8/10 Good

Heman

Liked: Cleanliness, amenities, property conditions & facilities
Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!
Stayed 9 nights in Jul 2025
Verified

10/10 Excellent

Timmy

Liked: Cleanliness, amenities, property conditions & facilities
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

Mustafa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
comfortable stay
Stayed 3 nights in Nov 2023
Verified

10/10 Excellent

Barbara

Liked: Cleanliness, staff & service, property conditions & facilities
Breakfast was great.
Stayed 3 nights in Jan 2024
Verified

10/10 Excellent

Timothy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great location in Durham!
Stayed 1 night in Apr 2024
Verified

10/10 Excellent

Kelly

Liked: Property conditions & facilities
Very nice staff and very clean!
Stayed 1 night in Feb 2024
Verified

10/10 Excellent

Gonzalo

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel convenient for visiting Duke
Stayed 1 night in Apr 2023