Cheap Vacations in Portsmouth

Choose two or more items and save on your trip:

Flight deals to Portsmouth

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Fri, Jan 23 - Sun, Jan 25
ATL
Atlanta
PGV
Greenville
$219 Roundtrip, found 2 days ago
$219
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Jan 23 from Atlanta to Greenville, returning Sun, Jan 25, priced at $219 found 2 days ago
Tue, Dec 30 - Thu, Jan 8
ATL
Atlanta
EWN
New Bern
$296 Roundtrip, found 4 days ago
$296
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Dec 30 from Atlanta to New Bern, returning Thu, Jan 8, priced at $296 found 4 days ago
Tue, Feb 17 - Tue, Feb 24
STL
St. Louis
OAJ
Jacksonville
$339 Roundtrip, found 4 days ago
$339
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Feb 17 from St. Louis to Jacksonville, returning Tue, Feb 24, priced at $339 found 4 days ago

Top rated hotels for your Portsmouth vacation

Beaufort Hotel NC

Beaufort Hotel NC

3.5 out of 5
2440 Lennoxville Rd Beaufort NC
Free Cancellation
Reserve now, pay when you stay
40.54 mi from city center
$142 nightly
The price is $160 total per night
$160 total
Dec 21 - Dec 22
Total with taxes and fees
With a stay at Beaufort Hotel NC in Beaufort, you'll be on the waterfront, just steps from Rachel Carson Reserve and a 5-minute drive from Beaufort Historic Site.
Pool
Pet friendly
The Anchorage Inn and Marina

The Anchorage Inn and Marina

2.5 out of 5
205 Irvin Garrish Hwy Ocracoke NC
5.5 mi from city center
$79 nightly
The price is $89 total per night
$89 total
Jan 15 - Jan 16, 2026
Total with taxes and fees
With a stay at The Anchorage Inn and Marina in Ocracoke, you'll be on the waterfront, within a 10-minute drive of Outer Banks Beaches and Ocracoke Preservation Museum.
Pool
Pet friendly
Pet friendly cottage perfect for a couple or small family.

Pet friendly cottage perfect for a couple or small family.

Ocracoke NC
5.69 mi from city center
Get rates
With a stay at this vacation home in Ocracoke, you'll be within a 10-minute drive of Outer Banks Beaches and British Cemetery.
Kitchen
Pet friendly
Don't see what you're looking for?
See all available properties in Portsmouth
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings with Flight + Hotel made on CheapTickets.com from as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.