Cheap Vacations in Panama

Choose two or more items and save on your trip:

Panama vacations

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $887, price is now $598 per person
$598
per person
Jun 11 - Jun 14
found 16 hours ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was $1,279, price is now $948 per person
$948
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,086, price is now $848 per person
$848
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $941, price is now $746 per person
$746
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Price was $1,214, price is now $975 per person
$975
per person
Jun 11 - Jun 14
found 16 hours ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Villa Caprichosa

Villa Caprichosa

3 out of 5
Price was $821, price is now $660 per person
$660
per person
May 15 - May 18
found 9 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
San Francisco
Price was $919, price is now $741 per person
$741
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Bella Vista
Price was $1,023, price is now $840 per person
$840
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Price was $1,109, price is now $914 per person
$914
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Casco Viejo
Price was $1,238, price is now $1,042 per person
$1,042
per person
May 16 - May 21
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

3-night Panama vacations

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $887, price is now $598 per person
$598
per person
Jun 11 - Jun 14
found 16 hours ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $1,279, price is now $948 per person
$948
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,086, price is now $848 per person
$848
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $941, price is now $746 per person
$746
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments

4 out of 5
Price was $2,339, price is now $1,865 per person
$1,865
per person
Jun 11 - Jun 14
found 6 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Price was $1,214, price is now $975 per person
$975
per person
Jun 11 - Jun 14
found 16 hours ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Villa Caprichosa

Villa Caprichosa

3 out of 5
Price was $821, price is now $660 per person
$660
per person
May 15 - May 18
found 9 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $919, price is now $741 per person
$741
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $1,023, price is now $840 per person
$840
per person
May 16 - May 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Price was $1,109, price is now $914 per person
$914
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Price was $1,028, price is now $865 per person
$865
per person
Jun 11 - Jun 14
found 6 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Price was $1,024, price is now $865 per person
$865
per person
Jun 11 - Jun 14
found 6 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

4-night Panama vacations

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $851, price is now $465 per person
$465
per person
Jun 8 - Jun 12
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Hotel Plaza Herrera

Hotel Plaza Herrera

4 out of 5
Save 100% on your flight
Price was $1,420, price is now $935 per person
$935
per person
May 29 - Jun 2
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Price was $843, price is now $662 per person
$662
per person
Jun 8 - Jun 12
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Price was $1,356, price is now $1,103 per person
$1,103
per person
May 21 - May 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Price was $1,608, price is now $1,311 per person
$1,311
per person
May 21 - May 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Irresistible City Center

Irresistible City Center

3.5 out of 5
Price was $1,106, price is now $902 per person
$902
per person
May 20 - May 24
found 4 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member

2.5 out of 5
Price was $1,133, price is now $930 per person
$930
per person
May 20 - May 24
found 4 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
Price was $1,319, price is now $1,091 per person
$1,091
per person
May 16 - May 20
found 16 hours ago
Roundtrip flight included
Washington (WAS) to Panama City (PTY)
Lesplanade by Wynwood House

Lesplanade by Wynwood House

3 out of 5
Price was $761, price is now $635 per person
$635
per person
May 29 - Jun 2
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Price was $1,319, price is now $1,105 per person
$1,105
per person
May 25 - May 29
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
The Westin Panama

The Westin Panama

4 out of 5
Price was $1,496, price is now $1,258 per person
$1,258
per person
May 25 - May 29
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Price was $1,177, price is now $992 per person
$992
per person
May 21 - May 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

5-night Panama vacations

Price found within the past 48 hours. Click for updated prices.
Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member

2.5 out of 5
Price was $939, price is now $696 per person
$696
per person
May 20 - May 25
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Panama City (PTY)
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,293, price is now $813 per person
$813
per person
May 16 - May 21
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $1,876, price is now $1,284 per person
$1,284
per person
May 18 - May 23
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,458, price is now $1,024 per person
$1,024
per person
May 18 - May 23
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,228, price is now $896 per person
$896
per person
May 18 - May 23
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,185, price is now $880 per person
$880
per person
May 18 - May 23
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $1,412, price is now $1,071 per person
$1,071
per person
May 18 - May 23
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Price was $1,848, price is now $1,446 per person
$1,446
per person
May 16 - May 21
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Price was $1,516, price is now $1,193 per person
$1,193
per person
May 18 - May 23
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
Price was $1,438, price is now $1,145 per person
$1,145
per person
May 20 - May 25
found 22 hours ago
Roundtrip flight included
Washington (WAS) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,238, price is now $1,000 per person
$1,000
per person
May 18 - May 23
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Irresistible City Center

Irresistible City Center

3.5 out of 5
Price was $917, price is now $743 per person
$743
per person
May 20 - May 25
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Panama City (PTY)

6-7 night Panama vacations

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,322, price is now $721 per person
$721
per person
May 31 - Jun 6
found 1 day ago
Roundtrip flight included
Washington (IAD) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,602, price is now $1,145 per person
$1,145
per person
May 31 - Jun 6
found 1 day ago
Roundtrip flight included
Washington (IAD) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $1,944, price is now $1,395 per person
$1,395
per person
May 31 - Jun 6
found 1 day ago
Roundtrip flight included
Washington (IAD) to Panama City (PTY)
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Save 100% on your flight
Price was $2,144, price is now $1,562 per person
$1,562
per person
May 22 - May 29
found 8 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,283, price is now $939 per person
$939
per person
May 31 - Jun 6
found 1 day ago
Roundtrip flight included
Washington (IAD) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,377, price is now $1,013 per person
$1,013
per person
May 25 - May 31
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Price was $1,867, price is now $1,427 per person
$1,427
per person
May 25 - May 31
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member

2.5 out of 5
Price was $1,349, price is now $1,052 per person
$1,052
per person
May 25 - May 31
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,444, price is now $1,159 per person
$1,159
per person
May 25 - May 31
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Irresistible City Center

Irresistible City Center

3.5 out of 5
Price was $1,322, price is now $1,083 per person
$1,083
per person
May 25 - May 31
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
MARINN PLACE Financial District

MARINN PLACE Financial District

3.5 out of 5
Price was $1,160, price is now $957 per person
$957
per person
May 31 - Jun 6
found 1 day ago
Roundtrip flight included
Washington (IAD) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Price was $1,600, price is now $1,321 per person
$1,321
per person
May 31 - Jun 6
found 1 day ago
Roundtrip flight included
Washington (IAD) to Panama City (PTY)

Top places to visit in Panama

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FlightsFlightsHotelsHotels

Panama City

Panama City

Flight deals to Panama

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Fri, Sep 11 - Tue, Sep 15
SJO
San José
PTY
Panama City
$275 Roundtrip, found 16 hours ago
$275
Roundtrip
found 16 hours ago
Select Copa flight, departing Fri, Sep 11 from San José to Panama City, returning Tue, Sep 15, priced at $275 found 16 hours ago
Mon, Aug 31 - Sat, Sep 5
MIA
Miami
PTY
Panama City
$352 Roundtrip, found 3 hours ago
$352
Roundtrip
found 3 hours ago
Select Copa flight, departing Mon, Aug 31 from Miami to Panama City, returning Sat, Sep 5, priced at $352 found 3 hours ago
Mon, May 4 - Mon, May 11
MEX
Mexico City
PTY
Panama City
$397 Roundtrip, found 3 hours ago
$397
Roundtrip
found 3 hours ago
Select Copa flight, departing Mon, May 4 from Mexico City to Panama City, returning Mon, May 11, priced at $397 found 3 hours ago

Top rated hotels for your Panama vacation

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Free Cancellation
Reserve now, pay when you stay
91.33 mi from city center
$138 nightly
The price is $151 total per night
$151 total
May 5 - May 6
Total with taxes and fees
Centrally located in Panama City, Hotel Riu Plaza Panama is within a 15-minute walk of Crown Casino and Fiesta Casino.
Pool
Breakfast included
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Free Cancellation
101.96 mi from city center
$133 nightly
The price is $146 total per night
$146 total
May 5 - May 6
Total with taxes and fees
Located in Tocumen, Crowne Plaza Panama Airport by IHG is within a 10-minute drive of Los Pueblos Commercial Center and Metromall Panama.
Pool
Free airport shuttle
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Free Cancellation
Reserve now, pay when you stay
92.79 mi from city center
$114 nightly
The price is $125 total per night
$125 total
May 1 - May 2
Total with taxes and fees
With a stay at Sheraton Grand Panama in Panama City (San Francisco), you'll be within a 5-minute drive of Multiplaza Pacific Mall and Cinta Costera.
Pool
Spa
Don't see what you're looking for?
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings with Flight + Hotel made on CheapTickets.com from 2019-04-01 - 2020-03-31 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.