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Cheap Louisiana Hotels

River's Edge Motel
201 Mansion St Louisiana MO
$80 nightly
The price is $91 total per night
$91 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.43 mi from city center
With a stay at River's Edge Motel in Louisiana, you'll be a 1-minute drive from Mississippi River and 9 minutes from Clarksville State Game Refuge.
Pet friendly
Parking included

The Eagles Nest Inn
215 Georgia St Louisiana MO
$105 nightly
The price is $119 total per night
$119 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
0.24 mi from city center
With a stay at The Eagles Nest Inn in Louisiana, you'll be a 1-minute drive from Mississippi River and 8 minutes from Clarksville State Game Refuge.
Parking included
Free WiFi

The Yellow Rose Historic Home
Louisiana MO
$308 nightly
The price is $316 total per night
$316 total
Dec 14 - Dec 15
Total with taxes and fees
0.2 mi from city center
With a stay at this vacation home in Louisiana, you'll be a 1-minute drive from Mississippi River and 9 minutes from Clarksville State Game Refuge.
Kitchen
Washer

Historic rooms near riverfront in downtown, Louisiana, MO
Louisiana MO
$133 nightly
The price is $133 total per night
$133 total
Dec 15 - Dec 16
Total with taxes and fees
0.24 mi from city center
With a stay at this bed & breakfast in Louisiana, you'll be a 1-minute drive from Mississippi River and 8 minutes from Clarksville State Game Refuge.
Air conditioning

Cozy room located in historic downtown with a 5 minute walk to the riverfront!
Louisiana MO
$133 nightly
The price is $140 total per night
$140 total
Dec 13 - Dec 14
Total with taxes and fees
0.24 mi from city center
With a stay at this bed & breakfast in Louisiana, you'll be a 1-minute drive from Mississippi River and 8 minutes from Clarksville State Game Refuge.
Air conditioning

Quality Inn & Suites Hannibal West
120 Lindsey Drive Hannibal MO
$79 nightly
The price is $92 total per night
$92 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
27.22 mi from city center
A stay at Quality Inn & Suites Hannibal West places you in the heart of Hannibal, a 3-minute drive from Hannibal Regional Hospital and 7 minutes from Molly Brown Museum and Home.
Pool
Hot Tub

Sleep Inn & Suites Hannibal West
105 Lakeside Dr Hannibal MO
$101 nightly
The price is $117 total per night
$117 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
27.36 mi from city center
A stay at Sleep Inn & Suites Hannibal West places you in the heart of Hannibal, within a 5-minute drive of Hospital Park and Hannibal Regional Hospital.
Pool
Breakfast included

Comfort Inn & Suites - Hannibal
4000 Market St Hannibal MO
$83 nightly
The price is $96 total per night
$96 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
24.81 mi from city center
With a stay at Comfort Inn & Suites - Hannibal, you'll be centrally located in Hannibal, within a 15-minute drive of Mississippi River and Sodalis Nature Preserve.
Pool
Hot Tub

Best Western On The River
401 North 3rd Street Hannibal MO
$101 nightly
The price is $116 total per night
$116 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
24.45 mi from city center
When you stay at Best Western On The River in Hannibal, you'll be in the historical district, within a 5-minute walk of Mississippi River and Jim's Journey: The Huck Finn Freedom Center.
Pool
Hot Tub

Days Inn by Wyndham Hannibal
4070 Market St Hannibal MO
$63 nightly
The price is $72 total per night
$72 total
Dec 25 - Dec 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
24.9 mi from city center
With a stay at Days Inn by Wyndham Hannibal in Hannibal, you'll be in the business district, within a 15-minute drive of Mississippi River and Sodalis Nature Preserve.
Breakfast included
Pet friendly

Motel 6 Hannibal, MO
123 Huckleberry Heights Dr Hannibal MO
$58 nightly
The price is $67 total per night
$67 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
24.85 mi from city center
With a stay at Motel 6 Hannibal, MO in Hannibal, you'll be within a 10-minute drive of Mississippi River and Indian Mounds Park.
Pet friendly
Parking included

Baymont by Wyndham Hannibal
4141 Market St Hannibal MO
$65 nightly
The price is $75 total per night
$75 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
24.87 mi from city center
With a stay at Baymont by Wyndham Hannibal, you'll be centrally located in Hannibal, within a 15-minute drive of Mississippi River and Sodalis Nature Preserve.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Louisiana hotels essential information
Accommodation | 82 hotels |
|---|---|
Lowest Price | $67 |
Highest Price | $316 |
Popular hotels | River's Edge Motel, The Eagles Nest Inn, The Yellow Rose Historic Home, Historic rooms near riverfront in downtown, Louisiana, MO, Cozy room located in historic downtown with a 5 minute walk to the riverfront!, Quality Inn & Suites Hannibal West, Sleep Inn & Suites Hannibal West, Comfort Inn & Suites - Hannibal, Best Western On The River, Days Inn by Wyndham Hannibal, Motel 6 Hannibal, MO, Baymont by Wyndham Hannibal |
Most Recent Louisiana Hotel Reviews

Quality Inn & Suites Hannibal West
5 out of 5
Posted 17 hours ago
CheapTickets Verified Review
"Everything was great "
A verified traveler stayed at Quality Inn & Suites Hannibal West
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