Cheap Vacations in Isla Grande

Choose two or more items and save on your trip:

3-night Isla Grande vacations

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,141, price is now $879 per person
$879
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $1,468, price is now $934 per person
$934
per person
Sep 23 - Sep 26
found 8 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,528, price is now $979 per person
$979
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,165, price is now $915 per person
$915
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5 out of 5
Price was $1,245, price is now $1,002 per person
$1,002
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $1,212, price is now $977 per person
$977
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Surfside Beachfront Suites by Playa Caracol Resorts

Surfside Beachfront Suites by Playa Caracol Resorts

3.5 out of 5
Price was $1,121, price is now $908 per person
$908
per person
Sep 23 - Sep 26
found 8 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,148, price is now $935 per person
$935
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Price was $1,396, price is now $1,141 per person
$1,141
per person
Sep 23 - Sep 26
found 8 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Sansara Surf and Yoga Resort - Retreat

Sansara Surf and Yoga Resort - Retreat

4.5 out of 5
Price was $1,349, price is now $1,110 per person
$1,110
per person
Sep 23 - Sep 26
found 8 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
The Buenaventura Golf & Beach Resort Panama, Autograph Collection

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

5 out of 5
Price was $1,176, price is now $971 per person
$971
per person
Sep 23 - Sep 26
found 8 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Villa Marina Hotel

Villa Marina Hotel

3.5 out of 5
Price was $1,076, price is now $891 per person
$891
per person
Sep 23 - Sep 26
found 8 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)

4-night Isla Grande vacations

Price found within the past 48 hours. Click for updated prices.
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Price was $1,136, price is now $899 per person
$899
per person
Sep 21 - Sep 25
found 12 hours ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $1,920, price is now $1,047 per person
$1,047
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,769, price is now $1,108 per person
$1,108
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,278, price is now $964 per person
$964
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $1,347, price is now $1,028 per person
$1,028
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Las Clementinas

Las Clementinas

3.5 out of 5
Price was $1,350, price is now $1,072 per person
$1,072
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,225, price is now $978 per person
$978
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,264, price is now $1,012 per person
$1,012
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Price was $1,572, price is now $1,287 per person
$1,287
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Price was $1,438, price is now $1,185 per person
$1,185
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Renaissance Panama City Hotel

Renaissance Panama City Hotel

5 out of 5
Price was $1,089, price is now $904 per person
$904
per person
Sep 18 - Sep 22
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Hotel San Felipe

Hotel San Felipe

4 out of 5
Price was $1,148, price is now $968 per person
$968
per person
Sep 13 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)

5-night Isla Grande vacations

Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá

Hotel Casa Panamá

4 out of 5
Price was $1,034, price is now $856 per person
$856
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $1,909, price is now $1,014 per person
$1,014
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Save 100% on your flight
Price was $1,979, price is now $1,151 per person
$1,151
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $1,448, price is now $1,053 per person
$1,053
per person
Sep 19 - Sep 24
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,291, price is now $962 per person
$962
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Las Clementinas

Las Clementinas

3.5 out of 5
Price was $1,389, price is now $1,077 per person
$1,077
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,347, price is now $1,049 per person
$1,049
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,275, price is now $1,015 per person
$1,015
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Price was $1,941, price is now $1,560 per person
$1,560
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Hotel San Felipe

Hotel San Felipe

4 out of 5
Price was $1,383, price is now $1,125 per person
$1,125
per person
Sep 26 - Oct 1
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Price was $1,238, price is now $1,010 per person
$1,010
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Price was $1,486, price is now $1,222 per person
$1,222
per person
Sep 12 - Sep 17
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)

6-7 night Isla Grande vacations

Price found within the past 48 hours. Click for updated prices.
Victoria Hotel and Suites Panama

Victoria Hotel and Suites Panama

3.5 out of 5
Price was $1,064, price is now $829 per person
$829
per person
Sep 14 - Sep 21
found 11 hours ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $2,158, price is now $1,233 per person
$1,233
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Save 100% on your flight
Price was $2,209, price is now $1,355 per person
$1,355
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,516, price is now $1,109 per person
$1,109
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Price was $1,295, price is now $985 per person
$985
per person
Sep 14 - Sep 21
found 11 hours ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,515, price is now $1,193 per person
$1,193
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
Las Clementinas

Las Clementinas

3.5 out of 5
Price was $1,652, price is now $1,309 per person
$1,309
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
Hotel San Felipe

Hotel San Felipe

4 out of 5
Price was $1,496, price is now $1,203 per person
$1,203
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
Renaissance Panama City Hotel

Renaissance Panama City Hotel

5 out of 5
Price was $1,301, price is now $1,057 per person
$1,057
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Price was $1,759, price is now $1,432 per person
$1,432
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Price was $1,925, price is now $1,580 per person
$1,580
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
Amarla Boutique Hotel Casco Viejo Adults Only

Amarla Boutique Hotel Casco Viejo Adults Only

3 out of 5
Price was $1,702, price is now $1,405 per person
$1,405
per person
Sep 26 - Oct 2
found 7 hours ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)

Flight deals to Isla Grande

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Tue, Sep 1 - Fri, Sep 4
SJO
San José
PTY
Panama City
$243 Roundtrip, found 10 hours ago
$243
Roundtrip
found 10 hours ago
Select Copa flight, departing Tue, Sep 1 from San José to Panama City, returning Fri, Sep 4, priced at $243 found 10 hours ago
Mon, Sep 14 - Tue, Sep 15
MEX
Mexico City
PTY
Panama City
$408 Roundtrip, found 1 day ago
$408
Roundtrip
found 1 day ago
Select Copa flight, departing Mon, Sep 14 from Mexico City to Panama City, returning Tue, Sep 15, priced at $408 found 1 day ago
Sat, Aug 29 - Tue, Sep 1
MIA
Miami
PTY
Panama City
$416 Roundtrip, found 10 hours ago
$416
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Sat, Aug 29 from Miami to Panama City, returning Tue, Sep 1, priced at $416 found 10 hours ago

Top rated hotels for your Isla Grande vacation

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande Isla Grande Colon
0.08 mi from city center
$437 nightly
The price is $481 total per night
$481 total
Aug 16 - Aug 17
Total with taxes and fees
When you stay at Ordovician Beach Resort in Isla Grande, you'll be in a national park and steps from Portobelo National Park.
On private beach
Pool
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
0.19 mi from city center
$89 nightly
The price is $98 total per night
$98 total
Aug 7 - Aug 8
Total with taxes and fees
When you stay at HOTEL ISLA GRANDE in Isla Grande, you'll be near the bay and steps from Portobelo National Park.
Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira Isla Grande Provincia de Colón
0.22 mi from city center
Get rates
When you stay at Hotel Cocotal in Isla Grande, you'll be steps from Portobelo National Park.
Don't see what you're looking for?
See all available properties in Isla Grande
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings with Flight + Hotel made on CheapTickets.com from 2019-04-01 - 2020-03-31 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.