Cheap Vacations in Isla Grande

Choose two or more items and save on your trip:

Isla Grande vacations

Price found within the past 48 hours. Click for updated prices.
Amarla Boutique Hotel Casco Viejo Adults Only

Amarla Boutique Hotel Casco Viejo Adults Only

3 out of 5
Casco Viejo
Price was $1,182, price is now $939 per person
$939
per person
Dec 21 - Dec 24
found 1 hour ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was $3,390, price is now $1,896 per person
$1,896
per person
Dec 18 - Dec 24
just found
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $2,597, price is now $1,457 per person
$1,457
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

3.5 out of 5
Casco Viejo
Price was $5,366, price is now $3,750 per person
$3,750
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Tocumen Airport
Price was $1,700, price is now $1,204 per person
$1,204
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,765, price is now $1,327 per person
$1,327
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3 out of 5
Casco Viejo
Price was $1,701, price is now $1,288 per person
$1,288
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Bella Vista
Price was $2,010, price is now $1,535 per person
$1,535
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Villas The Tides by Playa Caracol Resort

Villas The Tides by Playa Caracol Resort

3.5 out of 5
Price was $1,378, price is now $1,071 per person
$1,071
per person
Dec 25 - Dec 30
found 1 day ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Casa La Costa By Wynwood House

Casa La Costa By Wynwood House

3.5 out of 5
Casco Viejo
Price was $1,349, price is now $1,064 per person
$1,064
per person
Dec 26 - Jan 1
just found
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)

3-night Isla Grande vacations

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $842, price is now $578 per person
$578
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

3.5 out of 5
Price was $4,759, price is now $3,630 per person
$3,630
per person
Dec 30 - Jan 2
found 6 hours ago
Roundtrip non-stop flight included
Lima (LIM) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $2,183, price is now $1,119 per person
$1,119
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,243, price is now $681 per person
$681
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Price was $995, price is now $669 per person
$669
per person
Dec 21 - Dec 24
found 1 hour ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $992, price is now $715 per person
$715
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $865, price is now $632 per person
$632
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5 out of 5
Price was $1,017, price is now $762 per person
$762
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
American Trade Hotel

American Trade Hotel

4.5 out of 5
Price was $1,066, price is now $811 per person
$811
per person
Dec 21 - Dec 24
found 1 hour ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Renaissance Panama City Hotel

Renaissance Panama City Hotel

5 out of 5
Price was $781, price is now $618 per person
$618
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Amarla Boutique Hotel Casco Viejo Adults Only

Amarla Boutique Hotel Casco Viejo Adults Only

3 out of 5
Price was $1,182, price is now $939 per person
$939
per person
Dec 21 - Dec 24
found 1 hour ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $807, price is now $645 per person
$645
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)

4-night Isla Grande vacations

Price found within the past 48 hours. Click for updated prices.
Hotel San Pedro de Taboga

Hotel San Pedro de Taboga

3 out of 5
Price was $683, price is now $443 per person
$443
per person
Dec 6 - Dec 10
found 21 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $1,979, price is now $857 per person
$857
per person
Dec 16 - Dec 20
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,487, price is now $703 per person
$703
per person
Dec 11 - Dec 15
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $960, price is now $596 per person
$596
per person
Dec 11 - Dec 15
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $1,159, price is now $776 per person
$776
per person
Dec 11 - Dec 15
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $938, price is now $647 per person
$647
per person
Dec 11 - Dec 15
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
American Trade Hotel

American Trade Hotel

4.5 out of 5
Price was $1,475, price is now $1,036 per person
$1,036
per person
Dec 16 - Dec 20
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $926, price is now $674 per person
$674
per person
Dec 11 - Dec 15
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Price was $1,599, price is now $1,170 per person
$1,170
per person
Dec 11 - Dec 15
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

3.5 out of 5
Save 100% on your flight
Price was $1,088, price is now $806 per person
$806
per person
Dec 17 - Dec 21
found 4 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Hotel Casa Panamá

Hotel Casa Panamá

4 out of 5
Price was $734, price is now $554 per person
$554
per person
Dec 16 - Dec 20
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Price was $831, price is now $640 per person
$640
per person
Dec 17 - Dec 21
found 4 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)

5-night Isla Grande vacations

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,071, price is now $653 per person
$653
per person
Dec 15 - Dec 20
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,739, price is now $794 per person
$794
per person
Dec 15 - Dec 20
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $2,292, price is now $1,049 per person
$1,049
per person
Dec 15 - Dec 20
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,042, price is now $710 per person
$710
per person
Dec 15 - Dec 20
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $1,370, price is now $951 per person
$951
per person
Dec 15 - Dec 20
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

3.5 out of 5
Price was $5,366, price is now $3,750 per person
$3,750
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,049, price is now $771 per person
$771
per person
Dec 15 - Dec 20
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Price was $1,028, price is now $764 per person
$764
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3 out of 5
Price was $1,701, price is now $1,288 per person
$1,288
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
American Trade Hotel

American Trade Hotel

4.5 out of 5
Price was $1,718, price is now $1,305 per person
$1,305
per person
Dec 15 - Dec 20
found 1 day ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Villas The Tides by Playa Caracol Resort

Villas The Tides by Playa Caracol Resort

3.5 out of 5
Price was $1,378, price is now $1,071 per person
$1,071
per person
Dec 25 - Dec 30
found 1 day ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Hotel San Felipe

Hotel San Felipe

4 out of 5
Price was $1,021, price is now $794 per person
$794
per person
Dec 10 - Dec 15
found 1 day ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)

6-7 night Isla Grande vacations

Price found within the past 48 hours. Click for updated prices.
La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood

3 out of 5
Price was $1,087, price is now $887 per person
$887
per person
Dec 26 - Jan 1
just found
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $3,390, price is now $1,896 per person
$1,896
per person
Dec 18 - Dec 24
just found
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $2,597, price is now $1,457 per person
$1,457
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

3.5 out of 5
Save 100% on your flight
Price was $8,335, price is now $5,825 per person
$5,825
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,700, price is now $1,204 per person
$1,204
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,765, price is now $1,327 per person
$1,327
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $2,010, price is now $1,535 per person
$1,535
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
Casa La Costa By Wynwood House

Casa La Costa By Wynwood House

3.5 out of 5
Price was $1,349, price is now $1,064 per person
$1,064
per person
Dec 26 - Jan 1
just found
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
La Moderna Downtown Nights by Wynwood

La Moderna Downtown Nights by Wynwood

3 out of 5
Price was $1,182, price is now $952 per person
$952
per person
Dec 26 - Jan 1
just found
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
Casco View Life Residences

Casco View Life Residences

4 out of 5
Price was $1,208, price is now $979 per person
$979
per person
Dec 28 - Jan 4
found 1 day ago
Roundtrip flight included
Montego Bay (MBJ) to Panama City (PTY)
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Price was $1,623, price is now $1,315 per person
$1,315
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Panama City (PTY)
La Cuadra by Wynwood House

La Cuadra by Wynwood House

3 out of 5
Price was $2,151, price is now $1,761 per person
$1,761
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)

Flight deals to Isla Grande

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Thu, Nov 26 - Sat, Nov 28
SJO
San José
PTY
Panama City
$264 Roundtrip, just found
$264
Roundtrip
just found
Select Copa flight, departing Thu, Nov 26 from San José to Panama City, returning Sat, Nov 28, priced at $264 just found
Mon, Jan 11 - Sat, Jan 16
MEX
Mexico City
PTY
Panama City
$419 Roundtrip, found 10 hours ago
$419
Roundtrip
found 10 hours ago
Select Aeromexico flight, departing Mon, Jan 11 from Mexico City to Panama City, returning Sat, Jan 16, priced at $419 found 10 hours ago
Sat, Nov 28 - Mon, Dec 7
MIA
Miami
PTY
Panama City
$574 Roundtrip, found 3 days ago
$574
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 28 from Miami to Panama City, returning Mon, Dec 7, priced at $574 found 3 days ago

Top rated hotels for your Isla Grande vacation

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande Isla Grande Colon
0.08 mi from city center
$459 nightly
The price is $505 total per night
$505 total
Nov 7 - Nov 8
Total with taxes and fees
When you stay at Ordovician Beach Resort in Isla Grande, you'll be in a national park and steps from Portobelo National Park.
On private beach
Pool
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
0.19 mi from city center
$99 nightly
The price is $109 total per night
$109 total
Nov 7 - Nov 8
Total with taxes and fees
When you stay at HOTEL ISLA GRANDE in Isla Grande, you'll be near the bay and steps from Portobelo National Park.
Breakfast included
Spa
Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira Isla Grande Provincia de Colón
0.22 mi from city center
Get rates
When you stay at Hotel Cocotal in Isla Grande, you'll be steps from Portobelo National Park.
Breakfast included
Pet friendly
Don't see what you're looking for?
See all available properties in Isla Grande
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings with Flight + Hotel made on CheapTickets.com from 2019-04-01 - 2020-03-31 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.