Compare Cheap Hotels in Hartsville
Secret Bargains - Save an extra 10% or more on select hotels
Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Cheap Hartsville Hotels

Fairfield Inn by Marriott Hartsville
200 S 4th St Hartsville SC
$93 nightly
The price is $104 total per night
$104 total
Dec 27 - Dec 28
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.15 mi from city center
A stay at Fairfield Inn by Marriott Hartsville places you in the heart of Hartsville, within a 5-minute walk of Coker College and Hartsville Museum.

Hampton Inn & Suites Hartsville
203 East Carolina Ave. Hartsville SC
$122 nightly
The price is $137 total per night
$137 total
Dec 26 - Dec 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.17 mi from city center
A stay at Hampton Inn & Suites Hartsville places you in the heart of Hartsville, within a 5-minute walk of East Home Avenue Historic District and Coker College.

The Landmark Inn
1301 South 4th Street Hartsville SC
$76 nightly
The price is $84 total per night
$84 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.58 mi from city center
Located in Hartsville, The Landmark Inn is within a 5-minute drive of Hartsville Museum and Coker College.

The Mantissa Hotel
130 East Carolina Ave Hartsville SC
$188 nightly
The price is $211 total per night
$211 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.08 mi from city center
A stay at The Mantissa Hotel places you in the heart of Hartsville, steps from Hartsville Museum and 3 minutes by foot from Center Theatre.

Quality Inn
903 S 5th Street Hartsville SC
$62 nightly
The price is $70 total per night
$70 total
Jan 14 - Jan 15, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.94 mi from city center
With a stay at Quality Inn Hartsville in Hartsville, you'll be within a 5-minute drive of Hartsville Museum and Center Theatre.

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Hartsville SC
$138 nightly
The price is $150 total per night
$150 total
Dec 21 - Dec 22
Total with taxes and fees
5.69 mi from city center
Located in Hartsville, Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi is within a 15-minute drive of Segars-McKinnon Heritage Preserve and Kalmia Gardens.

Quiet lakefront condo with the best views on Prestwood lake.
Hartsville SC
0.97 mi from city center
Located in Hartsville, this condo is within a 5-minute drive of Lawton Park and Center Theatre.

Lakeside Living
Hartsville SC
5.7 mi from city center
Located in Hartsville, Lakeside Living is on the waterfront, within a 15-minute drive of Segars-McKinnon Heritage Preserve and Kalmia Gardens.

Lakefront Paradise!
Hartsville SC
0.97 mi from city center
Located in Hartsville, this condo is within a 5-minute drive of Lawton Park and Center Theatre.

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
$62 nightly
The price is $70 total per night
$70 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.32 mi from city center
When you stay at Howard Johnson by Wyndham Florence in Florence, you'll be near the airport and within a 5-minute drive of Dr. Eddie Floyd Tennis Center.

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
$85 nightly
The price is $95 total per night
$95 total
Dec 23 - Dec 24
Total with taxes and fees
Free Cancellation
18.35 mi from city center
When you stay at Park Inn by Radisson Florence, SC in Florence, you'll be near the airport and within a 5-minute drive of Dr. Eddie Floyd Tennis Center.

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
$99 nightly
The price is $110 total per night
$110 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.96 mi from city center
Located in Florence, Comfort Inn & Suites Florence Center Area is within a 5-minute drive of Florence Civic Center and Magnolia Mall.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Often, one of the most difficult things about booking a hotel is finding the best time to go. The cost of staying in hotels in could vary significantly, depending on the time of the year chosen. If you would like to figure out the most suitable time to take a trip then using CheapTickets could be the best option for you. We will be able to provide information on hotels in to ensure that you get the best deal possible. So if you are looking for a booking website that will streamline the process and offer good prices, then log in and get booking.
Hartsville hotels essential information
Accommodation | 174 hotels |
|---|---|
Lowest Price | $70 |
Highest Price | $211 |
Popular hotels | Fairfield Inn by Marriott Hartsville, Hampton Inn & Suites Hartsville, The Landmark Inn, The Mantissa Hotel, Quality Inn, Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi, Quiet lakefront condo with the best views on Prestwood lake., Lakeside Living, Lakefront Paradise!, Howard Johnson by Wyndham Florence, Park Inn by Radisson Florence, SC, Comfort Inn & Suites Florence Center Area |
Most Recent Hartsville Hotel Reviews

Comfort Inn & Suites Florence Center Area
5 out of 5
Posted 3 days ago
CheapTickets Verified Review
"Plenty of space, but it also had a cozy/comfortable feel. Staff was super friendly and there was a good variety of items available for the free breakfast.
Everything was clean, the bed was very comfortable..
Just 5-10 minutes from 95, and plenry of food and shopping options nearby."
A verified traveler stayed at Comfort Inn & Suites Florence Center Area
- Types of Hotels
- Top 20 Hartsville Hotels
- Hotels Near Hartsville
- Top Hotel Brands
- Hotels By Star Rating
- Cities near Hartsville
- Hotels with WiFi in Hartsville
- Hotels with Restaurants in Hartsville
- Hotels with Free Parking in Hartsville
- Hotels with Air Conditioning in Hartsville
- Business Hotels in Hartsville
- Hotels with Free Breakfast in Hartsville
- Hotels with Pools in Hartsville
- Hotels with Bars in Hartsville
- Hotels with Shopping in Hartsville
- Hotels with a Gym in Hartsville
- Kid Friendly Hotels in Hartsville
- Pet Friendly Hotels in Hartsville
- Hotels with Room Service in Hartsville
- Boutique Hotels in Hartsville
- Adventure Sport Hotels in Hartsville
- Hotels with a Wedding Venue in Hartsville
- Spa Resorts & Hotels in Hartsville
- Beach Resorts & Hotels in Hartsville
- Luxury Hotels in Hartsville
More to Explore in Hartsville
Top Picks
Hotels
- Hotels in Anderson
- Hotels in North Charleston
- Hotels in Sullivan's Island
- Hotels in Clemson
- Hotels in Mount Pleasant
- Hotels in Summerville
- Hotels in Surfside Beach
- Hotels in Charleston
- Hotels in Myrtle Beach
- Hotels in Greenville
- Hotels in Pawleys Island
- Hotels in Columbia
- Hotels in Daufuskie Island
- Hotels in Kiawah Island
- Hotels in Folly Beach
- 4 Star Hotels in Myrtle Beach
- Hotels in North Myrtle Beach
Flights






