Compare Hotels on the Lake in South Carolina

When you stay at Clemson University's James F. Martin Inn in Clemson, you'll be connected to the convention center, just steps from Clemson University and Lake Hartwell.

When you stay at Hampton Inn Columbia I-26/Harbison Blvd. in Columbia, you'll be in the business district, within a 15-minute drive of University of South Carolina and Lake Murray.

With a stay at Myrtlewood Villas in Myrtle Beach (Central Myrtle Beach), you'll be within a 5-minute drive of Broadway at the Beach and Ripley's Aquarium.

Located in Kiawah Island, Charleston Kiawah Island/Andell Inn is next to a golf course, a 3-minute walk from Freshfields Village and 13 minutes by foot from Bohicket Marina.

When you stay at this vacation home in Hilton Head Island, you'll be by the sea, within a 10-minute drive of Palmetto Dunes Club and Coligny Beach.

When you stay at this vacation home in North Charleston, you'll be on the waterfront, within a 5-minute drive of Charleston Tanger Outlets and North Charleston Coliseum and Performing Arts Center.

When you stay at Days Inn by Wyndham Columbia in Columbia, you'll be in the historical district, within a 10-minute drive of University of South Carolina and Riverbanks Zoo and Garden.

When you stay at this villa in Hilton Head Island, you'll be next to a golf course, within a 5-minute drive of Palmetto Dunes Club and Coligny Beach.