Compare Business Hotels in South America
Secret Bargains - Save an extra 10% or more on select Business Hotels
Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Featured South America Business Hotels

Radisson Blu Plaza El Bosque Santiago
Av. Manquehue 656 Santiago Region Metropolitana
$126 nightly
The price is $126 total per night
$126 total
Dec 19 - Dec 20
Free Cancellation
With a stay at Radisson Blu Plaza El Bosque Santiago in Santiago (Las Condes), you'll be steps from Parque Araucano and 7 minutes by foot from KidZania Santiago.
Pool
Breakfast included

Grand Hyatt Sao Paulo
Avenida das Nacoes Unidas 13.301 São Paulo SP
$197 nightly
The price is $207 total per night
$207 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Grand Hyatt Sao Paulo in São Paulo (Itaim Bibi), you'll be a 5-minute drive from Shopping Eldorado and 7 minutes from Ibirapuera Park.
Pool
Hot Tub

Pullman Santiago Vitacura
Av. Vitacura 3201 Santiago Region Metropolitana
$95 nightly
The price is $95 total per night
$95 total
Jan 1 - Jan 2, 2026
Free Cancellation
Reserve now, pay when you stay
Located in Santiago (Vitacura), Pullman Santiago Vitacura is within a 5-minute walk of Bicentennial Park and within a 5-minute drive of Costanera Center.
Pool
Pet friendly

NH Collection Medellín Royal
Carrera 42 No 5 Sur 130 Medellín Antioquia
$85 nightly
The price is $85 total per night
$85 total
Dec 14 - Dec 15
Free Cancellation
Reserve now, pay when you stay
With a stay at NH Collection Medellín Royal in Medellín (El Poblado), you'll be within a 5-minute walk of Santafé Mall and Oviedo Shopping Center.
Pool
Spa

NM Lima Hotel
Av Pardo y Aliaga 330 Lima Lima
$86 nightly
The price is $86 total per night
$86 total
Dec 6 - Dec 7
Free Cancellation
Reserve now, pay when you stay
With a stay at NM Lima Hotel, you'll be centrally located in Lima, within a 10-minute drive of Larcomar Shopping Center and Jockey Plaza.
Breakfast included
Parking included

Pullman Lima San Isidro
Av. Jorge Basadre 595, San Isidro Lima Lima
$110 nightly
The price is $110 total per night
$110 total
Jan 2 - Jan 3, 2026
Free Cancellation
Reserve now, pay when you stay
With a stay at Pullman Lima San Isidro in Lima (San Isidro), you'll be within a 10-minute drive of Larcomar Shopping Center and Jockey Plaza.
Pool
Hot Tub

Hotel Plaza El Bosque Ebro
Ebro 2828, Las Condes Santiago Region Metropolitana
$128 nightly
The price is $128 total per night
$128 total
Dec 19 - Dec 20
Free Cancellation
Reserve now, pay when you stay
Located in Santiago (Las Condes), Hotel Plaza El Bosque Ebro is within a 10-minute walk of Costanera Center and Gran Torre Santiago.
Pool
Breakfast included

Hotel Madero Buenos Aires, WorldHotels Elite
Rosario Vera Peñaloza 360 – Dique 2 Buenos Aires Capital Federal
$220 nightly
The price is $223 total per night
$223 total
Jan 5 - Jan 6, 2026
Free Cancellation
Reserve now, pay when you stay
Centrally located in Buenos Aires, Hotel Madero Buenos Aires, WorldHotels Elite is within a 15-minute walk of Puerto Madero Casino and Women's Bridge.
Pool
Hot Tub

Regal Pacific Buenos Aires
25 De Mayo, 764 Buenos Aires Capital Federal
Free Cancellation
Reserve now, pay when you stay
A stay at Regal Pacific Buenos Aires places you in the heart of Buenos Aires, within a 5-minute walk of Galerias Pacifico and Florida Street.
Pool
Spa

GHL Hotel Capital
Calle 25B N69 A-50 Bogotá Distrito Capital
$77 nightly
The price is $77 total per night
$77 total
Dec 14 - Dec 15
Free Cancellation
Reserve now, pay when you stay
With a stay at GHL Hotel Capital in Bogotá (Fontibon), you'll be a 2-minute drive from Salitre Plaza Shopping Mall and 5 minutes from U.S. Embassy Bogotá.
Hot Tub
Breakfast included

Courtyard by Marriott Guayaquil
Av. Francisco De Orellana #236 Guayaquil Guayas
$72 nightly
The price is $81 total per night
$81 total
Dec 26 - Dec 27
Free Cancellation
Reserve now, pay when you stay
With a stay at Courtyard by Marriott Guayaquil in Guayaquil (Kennedy), you'll be a 1-minute drive from San Marino Mall and 5 minutes from Centennial Park.
Pool
Spa

Hotel Cadoro Sao Paulo
Rua Augusta, 129 São Paulo
$108 nightly
The price is $114 total per night
$114 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hotel Cadoro Sao Paulo, you'll be centrally located in São Paulo, steps from Rua Augusta and within a 5-minute drive of Paulista Avenue.
Pool
Free WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South America Business Hotels essential information
Business Hotels in South America |
7817 |
|---|---|
Highest price | $223 |
Cheapest price | $77 |
Total number of hotels in South America | 116,460 |
Popular hotels | Radisson Blu Plaza El Bosque Santiago, Grand Hyatt Sao Paulo, Pullman Santiago Vitacura, NH Collection Medellín Royal, NM Lima Hotel, Pullman Lima San Isidro, Hotel Plaza El Bosque Ebro, Hotel Madero Buenos Aires, WorldHotels Elite, Regal Pacific Buenos Aires, GHL Hotel Capital, Courtyard by Marriott Guayaquil, Hotel Cadoro Sao Paulo |
Most Recent South America Hotel Reviews

Regal Pacific Buenos Aires
5 out of 5
Posted 9 days ago
CheapTickets Verified Review
"Staff was helpful and friendly. Location was good and safe. Walkable to restaurants. Breakfast was good and convenient. Room was clean, but the room and some furniture looks quite dated."
A verified traveler stayed at Regal Pacific Buenos Aires
More Business Hotels
Types of Hotels
More to Explore in South America
Top Picks
Hotels
Flights
Packages
- Cheap Chile Packages
- Cheap Peru Packages
- Cheap Ecuador Packages
- Cheap Bolivia Packages
- Cheap Guyana Packages
- Cheap Falkland Islands Packages
- Cheap French Guiana Packages
- Cheap Paraguay Packages
- Cheap Argentina Packages
- Cheap Las Vegas Packages
- Cheap Colombia Packages
- Cheap Brazil Packages
- Cheap Ireland Packages





