Compare Cheap Hotels in De Soto
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Cheap De Soto Hotels

82 Acre Hobby Farm with Lincoln Log Cabin
De Soto MO
$265 nightly
The price is $275 total per night
$275 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
3.18 mi from city center
Located in De Soto, this cabin is in a rural location, within a 10-minute drive of Eastside Community Park and Joachim Park.
Kitchen
Washer

Secluded cabin on private property
De Soto MO
6.99 mi from city center
When you stay at this cabin in De Soto, you'll be 3 minutes by foot from Big River.
Kitchen
Washer

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
$53 nightly
The price is $60 total per night
$60 total
Dec 26 - Dec 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
25.98 mi from city center
Located in Farmington, Baymont Inn and Suites by Wyndham Farmington, MO is in the historical district, within a 15-minute drive of Crown Pointe Golf Club and St. Joe State Park.
Pool
Breakfast included

Pear Tree Inn St. Louis Arnold
1201 Drury Ln Arnold MO
$90 nightly
The price is $104 total per night
$104 total
Dec 23 - Dec 24
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
23.12 mi from city center
With a stay at Pear Tree Inn St. Louis Arnold in Arnold, you'll be within a 15-minute drive of Mississippi River and BounceU of St. Louis.
Pool
Breakfast included

Drury Inn & Suites St. Louis Arnold
3800 State Rt 141 Arnold MO
$123 nightly
The price is $142 total per night
$142 total
Dec 24 - Dec 25
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
23.11 mi from city center
With a stay at Drury Inn & Suites St. Louis Arnold in Arnold, you'll be within a 15-minute drive of Mississippi River and Arnold Historical Society & Museum.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
1001 Veterans Blvd Festus MO
$93 nightly
The price is $106 total per night
$106 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
9.7 mi from city center
Located in Festus, La Quinta Inn & Suites by Wyndham Festus - St. Louis South is in a rural location, within a 5-minute drive of Jorkerst Memorial Park and Festus Public Library.
Breakfast included
Pet friendly

Super 8 by Wyndham Farmington
930 Valley Creek Dr Farmington MO
$53 nightly
The price is $60 total per night
$60 total
Dec 25 - Dec 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
24.78 mi from city center
With a stay at Super 8 by Wyndham Farmington in Farmington, you'll be within a 5-minute drive of Farmington Mineral Area Shopping Center and Harlan Park.
Pool
Breakfast included

Baymont by Wyndham Festus
1200 W. Gannon Drive Festus MO
$77 nightly
The price is $87 total per night
$87 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
9.57 mi from city center
With a stay at Baymont by Wyndham Festus in Festus, you'll be 8.7 mi (14.1 km) from Villa Antonio Winery and 25.6 mi (41.2 km) from Grant's Farm.
Pool
Breakfast included

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
1802 Gamel Cemetery Road Festus MO
$127 nightly
The price is $145 total per night
$145 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
9.27 mi from city center
With a stay at Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG in Festus, you'll be within a 5-minute drive of Jorkerst Memorial Park and Sunset Park.
Pool
Breakfast included

Hampton Inn Farmington
850 Valley Creek Dr Farmington MO
$107 nightly
The price is $122 total per night
$122 total
Dec 25 - Dec 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
24.72 mi from city center
With a stay at Hampton Inn Farmington in Farmington, you'll be within a 5-minute drive of Farmington Mineral Area Shopping Center and Harlan Park.
Pool
Hot Tub

Super 8 by Wyndham Potosi
820 E High St Potosi MO
$55 nightly
The price is $60 total per night
$60 total
Dec 20 - Dec 21
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.84 mi from city center
Located in Potosi, Super 8 by Wyndham Potosi is within a 5-minute drive of Washington County Courthouse and St. James Catholic Church.
Breakfast included
Pet friendly

Comfort Inn Festus - St Louis South
1303 Veterans Blvd Festus MO
$78 nightly
The price is $88 total per night
$88 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
9.49 mi from city center
With a stay at Comfort Inn Festus - St Louis South in Festus, you'll be within a 10-minute drive of Mississippi River and Jorkerst Memorial Park.
Breakfast included
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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De Soto hotels essential information
Accommodation | 174 hotels |
|---|---|
Lowest Price | $60 |
Highest Price | $275 |
Popular hotels | 82 Acre Hobby Farm with Lincoln Log Cabin, Secluded cabin on private property, Baymont Inn and Suites by Wyndham Farmington, MO, Pear Tree Inn St. Louis Arnold, Drury Inn & Suites St. Louis Arnold, La Quinta Inn & Suites by Wyndham Festus - St. Louis South, Super 8 by Wyndham Farmington, Baymont by Wyndham Festus, Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG, Hampton Inn Farmington, Super 8 by Wyndham Potosi, Comfort Inn Festus - St Louis South |
Most Recent De Soto Hotel Reviews

Drury Inn & Suites St. Louis Arnold
5 out of 5
Posted 3 days ago
CheapTickets Verified Review
"I always check in late. The overnight staff is top notch. One time they even called me to make sure I was okay and not lost. I will ALWAYS stay at this Drury Inn! "
A verified traveler stayed at Drury Inn & Suites St. Louis Arnold
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