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Independent in Cairo

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road Cairo IL
$68 nightly
The price is $76 total per night
$76 total
Jul 10 - Jul 11
Total with taxes and fees
Free Cancellation
2.68 mi from city center
With a stay at Quality Inn Cairo I-57 in Cairo, you'll be within a 15-minute drive of Mississippi River and Ohio River Valley.
Breakfast included
Pet friendly
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
$60 nightly
The price is $66 total per night
$66 total
Jul 12 - Jul 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.04 mi from city center
With a stay at Super 8 by Wyndham Charleston/Sikeston East MO, you'll be centrally located in Charleston, 10.3 mi (16.6 km) from Mississippi River and 14 mi (22.5 km) from Ohio River.
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL
$187 nightly
The price is $198 total per night
$198 total
Jun 21 - Jun 22
Total with taxes and fees
10.85 mi from city center
This cabin is 0.3 mi (0.4 km) from Shawnee National Forest and 6.2 mi (9.9 km) from Ohio River Valley.
Kitchen
Pet friendly
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

2.5 out of 5
102 Drake St Charleston MO
$75 nightly
The price is $83 total per night
$83 total
Jun 17 - Jun 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
11.71 mi from city center
When you stay at The Riverstone Hotel Charleston-Sikeston in Charleston, you'll be 13 minutes by car from City of Miner Convention Center.
Pool
Breakfast included
La Center Motel

La Center Motel

2 out of 5
474 W Kentucky Dr La Center KY
$65 nightly
The price is $70 total per night
$70 total
Jun 17 - Jun 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
11.79 mi from city center
When you stay at La Center Motel in La Center, you'll be 13 minutes by car from Ohio River Valley.
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

Olive Branch IL
$133 nightly
The price is $140 total per night
$140 total
Jun 17 - Jun 18
Total with taxes and fees
14.88 mi from city center
This cabin is 0.4 mi (0.7 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.
Air conditioning
Lake view
Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre

Dongola IL
$265 nightly
The price is $281 total per night
$281 total
Jun 20 - Jun 21
Total with taxes and fees
24.79 mi from city center
Located in Dongola, this cabin is on a lake, within a 15-minute drive of Dongola Lake and Dongola Public Library.
Kitchen
Washer
Wandering the wineries or hitting the hills? We got you! Come stay!

Wandering the wineries or hitting the hills? We got you! Come stay!

Tamms IL
17.4 mi from city center
When you stay at this vacation home in Tamms, you'll be steps from Shawnee National Forest.
Kitchen
Washer
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Kevil KY
17.75 mi from city center
With a stay at this vacation home in Kevil, you'll be 16.8 mi (27.1 km) from Mississippi River and 17.7 mi (28.5 km) from Paducah Riverwalk.
Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall

Kevil KY
$181 nightly
The price is $205 total per night
$205 total
Jun 21 - Jun 22
Total with taxes and fees
18.71 mi from city center
With a stay at this vacation home in Kevil, you'll be within a 15-minute drive of Ohio River Valley and Paul Rowton Indoor Tennis Center.
Kitchen
Washer
Fabulous cabin with AC in charming Tamms

Fabulous cabin with AC in charming Tamms

Tamms IL
20.46 mi from city center
With a stay at this cabin in Tamms, you'll be a 3-minute drive from Shawnee National Forest and 10 minutes from Ullin City Hall.
The Rested Duck Mallard Room

The Rested Duck Mallard Room

Olive Branch IL
$133 nightly
The price is $140 total per night
$140 total
Jun 17 - Jun 18
Total with taxes and fees
14.88 mi from city center
This cabin is 0.4 mi (0.7 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.
Air conditioning
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cairo hotels essential information

Accommodation
28 hotels
Lowest Price
$66
Highest Price
$281
Popular hotels
Quality Inn Cairo I-57, Super 8 by Wyndham Charleston/Sikeston East MO, Peaceful secluded cabin located near Horseshoe Lake , The Riverstone Hotel Charleston-Sikeston, La Center Motel, Cozy cabins on beautiful Horseshoe Lake, Charming cottage overlooking Lake Acre, Wandering the wineries or hitting the hills? We got you! Come stay!, Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286, Charming Home just minutes from Interstate and Mall, Fabulous cabin with AC in charming Tamms, The Rested Duck Mallard Room

Most Recent Cairo Hotel Reviews

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

4 out of 5
Posted 5 days ago
CheapTickets Verified Review
"The outside of the hotel needs some work The breakfast needed more than instant oatmeal for breakfast. Muffins wrapped separately would have been nice. Banana along with the apples. Cold cereals in little bowls. Just anything more than what they had."
A verified traveler stayed at Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO

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