Compare Cheap Hotels Near Cairo (CIR) Airport

Name: Drury Inn & Suites Sikeston, MO
Price range: $103 total

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Cheap Cairo Regional Hotels

Quality Inn Cairo I-57

13201 Kessler Road Cairo IL

$70 nightly

$78 total

Dec 13 - Dec 14

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

2.07 mi from Cairo Regional

Located in Cairo, Quality Inn Cairo I-57 is a 2-minute drive from Ohio River and 5 minutes from Ohio River Valley.

Breakfast included

Pet friendly

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL

$206 nightly

$218 total

Dec 7 - Dec 8

Total with taxes and fees

6.27 mi from Cairo Regional

This cabin is 0.3 mi (0.4 km) from Shawnee National Forest and 6.2 mi (9.9 km) from Ohio River Valley.

Kitchen

Pet friendly

Cozy cabins on beautiful Horseshoe Lake

Olive Branch IL

$133 nightly

$140 total

Dec 7 - Dec 8

Total with taxes and fees

10.24 mi from Cairo Regional

This cabin is 0.5 mi (0.8 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.

Air conditioning

Lake view

The Rested Duck Mallard Room

Olive Branch IL

$145 nightly

$154 total

Dec 22 - Dec 23

Total with taxes and fees

10.24 mi from Cairo Regional

This cabin is 0.5 mi (0.8 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.

Air conditioning

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

$59 nightly

$65 total

Dec 6 - Dec 7

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

11.2 mi from Cairo Regional

With a stay at Super 8 by Wyndham Charleston/Sikeston East MO, you'll be centrally located in Charleston, 10.3 mi (16.6 km) from Mississippi River and 12.7 mi (20.4 km) from Fort Defiance State Park.

Breakfast included

Pet friendly

Eagle Inn Charleston

2811 East Marshall Street Charleston MO

$60 nightly

$67 total

Dec 6 - Dec 7

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

10.69 mi from Cairo Regional

With a stay at Eagle Inn Charleston in Charleston, you'll be 10.1 mi (16.3 km) from Mississippi River and 11.7 mi (18.9 km) from Fort Defiance State Park.

Pet friendly

Parking included

Quality Inn Charleston - Sikeston

102 Drake St Charleston MO

$64 nightly

$71 total

Dec 13 - Dec 14

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

12.65 mi from Cairo Regional

When you stay at Quality Inn Charleston - Sikeston in Charleston, you'll be 13 minutes by car from City of Miner Convention Center.

Breakfast included

Pet friendly

Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.

Tamms IL

12.81 mi from Cairo Regional

When you stay at this vacation home in Tamms, you'll be steps from Shawnee National Forest.

Kitchen

Washer

La Center Motel

474 W Kentucky Dr La Center KY

$65 nightly

$70 total

Jan 4 - Jan 5, 2026

Total with taxes and fees

13.53 mi from Cairo Regional

When you stay at La Center Motel in La Center, you'll be 13 minutes by car from Ohio River Valley.

Parking included

Free WiFi

Solar Eclipse Festival at our Campground at Benton Speedway. April 6-8th 2024.

Benton MO

15.45 mi from Cairo Regional

When you stay at this campground in Benton, you'll be 14 minutes by car from Front Street Studio & Art Gallery.

Pet friendly

Fabulous cabin with AC in charming Tamms

Tamms IL

16.2 mi from Cairo Regional

Located in Tamms, this cabin is a 3-minute drive from Shawnee National Forest and 10 minutes from Ullin City Hall.

Washer

Dryer

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

$90 nightly

$103 total

Dec 9 - Dec 10

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

20.76 mi from Cairo Regional

A stay at Drury Inn & Suites Sikeston, MO places you in the heart of Sikeston, a 1-minute drive from City of Miner Convention Center and 5 minutes from Sikeston Depot Museum.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Cairo Regional hotels essential information

Accommodation	80 hotels
Lowest Price	$65
Highest Price	$218
Popular hotels	Quality Inn Cairo I-57, Peaceful secluded cabin located near Horseshoe Lake , Cozy cabins on beautiful Horseshoe Lake, The Rested Duck Mallard Room, Super 8 by Wyndham Charleston/Sikeston East MO, Eagle Inn Charleston, Quality Inn Charleston - Sikeston, Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout., La Center Motel, Solar Eclipse Festival at our Campground at Benton Speedway. April 6-8th 2024., Fabulous cabin with AC in charming Tamms, Drury Inn & Suites Sikeston, MO