Compare Cheap Hotels Near Cairo (CIR) Airport
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Cheap Cairo Regional Hotels

Quality Inn Cairo I-57
13201 Kessler Road Cairo IL
$79 nightly
The price is $87 total per night
$87 total
Apr 29 - Apr 30
Total with taxes and fees
Free Cancellation
2.08 mi from Cairo Regional
With a stay at Quality Inn Cairo I-57 in Cairo, you'll be within a 15-minute drive of Mississippi River and Ohio River Valley.
Breakfast included
Pet friendly

Peaceful secluded cabin located near Horseshoe Lake
Miller City IL
$159 nightly
The price is $169 total per night
$169 total
Apr 26 - Apr 27
Total with taxes and fees
6.27 mi from Cairo Regional
This cabin is 0.3 mi (0.4 km) from Shawnee National Forest and 6.2 mi (9.9 km) from Ohio River Valley.
Kitchen
Pet friendly

Cozy cabins on beautiful Horseshoe Lake
Olive Branch IL
$133 nightly
The price is $140 total per night
$140 total
Apr 25 - Apr 26
Total with taxes and fees
10.24 mi from Cairo Regional
This cabin is 0.4 mi (0.7 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.
Air conditioning
Lake view

The Rested Duck Mallard Room
Olive Branch IL
$145 nightly
The price is $154 total per night
$154 total
May 25 - May 26
Total with taxes and fees
10.24 mi from Cairo Regional
This cabin is 0.4 mi (0.7 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.
Air conditioning

Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
$65 nightly
The price is $72 total per night
$72 total
Apr 29 - Apr 30
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
11.2 mi from Cairo Regional
With a stay at Super 8 by Wyndham Charleston/Sikeston East MO, you'll be centrally located in Charleston, 10.3 mi (16.6 km) from Mississippi River and 20.5 mi (33 km) from Shawnee National Forest.
Breakfast included
Pet friendly

Eagle Inn Charleston
2811 East Marshall Street Charleston MO
$55 nightly
The price is $61 total per night
$61 total
May 2 - May 3
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.69 mi from Cairo Regional
With a stay at Eagle Inn Charleston in Charleston, you'll be 10.1 mi (16.3 km) from Mississippi River and 20.6 mi (33.1 km) from Shawnee National Forest.
Pet friendly
Parking included

The Riverstone Hotel Charleston-Sikeston
102 Drake St Charleston MO
$75 nightly
The price is $83 total per night
$83 total
Apr 25 - Apr 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
12.65 mi from Cairo Regional
When you stay at The Riverstone Hotel Charleston-Sikeston in Charleston, you'll be 13 minutes by car from City of Miner Convention Center.
Breakfast included
Pet friendly

May graduates, hikers, bike riders, fisherman, side-by-siders--we got you!
Tamms IL
12.81 mi from Cairo Regional
When you stay at this vacation home in Tamms, you'll be steps from Shawnee National Forest.
Kitchen
Washer

La Center Motel
474 W Kentucky Dr La Center KY
$65 nightly
The price is $70 total per night
$70 total
Apr 26 - Apr 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
13.53 mi from Cairo Regional
When you stay at La Center Motel in La Center, you'll be 13 minutes by car from Ohio River Valley.
Parking included
Free WiFi

Welcoming 4-bedroom house with AC in charming La Center
La Center KY
$242 nightly
The price is $259 total per night
$259 total
May 25 - May 26
Total with taxes and fees
14.06 mi from Cairo Regional
When you stay at this vacation home in La Center, you'll be 15 minutes by car from Ohio River Valley.
Washer
Dryer

Solar Eclipse Festival at our Campground at Benton Speedway. April 6-8th 2024.
Benton MO
15.45 mi from Cairo Regional
When you stay at this campground in Benton, you'll be 14 minutes by car from Front Street Studio & Art Gallery.
Pet friendly

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$102 nightly
The price is $117 total per night
$117 total
Apr 28 - Apr 29
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
20.76 mi from Cairo Regional
A stay at Drury Inn & Suites Sikeston, MO places you in the heart of Sikeston, a 1-minute drive from City of Miner Convention Center and 5 minutes from Sikeston Depot Museum.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cairo Regional hotels essential information
Accommodation | 87 hotels |
|---|---|
Lowest Price | $61 |
Highest Price | $259 |
Popular hotels | Quality Inn Cairo I-57, Peaceful secluded cabin located near Horseshoe Lake , Cozy cabins on beautiful Horseshoe Lake, The Rested Duck Mallard Room, Super 8 by Wyndham Charleston/Sikeston East MO, Eagle Inn Charleston, The Riverstone Hotel Charleston-Sikeston, May graduates, hikers, bike riders, fisherman, side-by-siders--we got you!, La Center Motel, Welcoming 4-bedroom house with AC in charming La Center, Solar Eclipse Festival at our Campground at Benton Speedway. April 6-8th 2024., Drury Inn & Suites Sikeston, MO |
Most Recent Cairo Regional Hotel Reviews

The Riverstone Hotel Charleston-Sikeston
1 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Coffee "
A verified traveler stayed at The Riverstone Hotel Charleston-Sikeston
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