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Cheap Cairo Regional Hotels

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road, Cairo, IL
The price is $66 per night
$66
per night
Oct 14 - Oct 15
Free Cancellation
Reserve now, pay when you stay
2.07 mi from Cairo Regional
Located in Cairo, Quality Inn Cairo I-57 is a 2-minute drive from Ohio River and 8 minutes from Mound City National Cemetery.
Super 8 by Wyndham Charleston MO

Super 8 by Wyndham Charleston MO

2 out of 5
310 S Story St, Charleston, MO
The price is $66 per night
$66
per night
Oct 2 - Oct 3
Free Cancellation
Reserve now, pay when you stay
11.2 mi from Cairo Regional
A stay at Super 8 by Wyndham Charleston MO places you in the heart of Charleston, and within a 15-minute drive of The Book Bug.
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

The price is $110 per night
$110
per night
Sep 30 - Oct 1
10.24 mi from Cairo Regional
This cabin is 0.5 mi (0.8 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.
The Rested Duck Mallard Room

The Rested Duck Mallard Room

The price is $110 per night
$110
per night
Sep 30 - Oct 1
10.24 mi from Cairo Regional
This cabin is 0.5 mi (0.8 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.
Eagle Inn Charleston

Eagle Inn Charleston

2 out of 5
2811 East Marshall Street, Charleston, MO
The price is $70 per night
$70
per night
Oct 1 - Oct 2
Free Cancellation
Reserve now, pay when you stay
10.69 mi from Cairo Regional
With a stay at Eagle Inn Charleston in Charleston, you'll be 10.1 mi (16.3 km) from Mississippi River and 20.6 mi (33.1 km) from Shawnee National Forest.
Quality Inn Charleston I-57

Quality Inn Charleston I-57

2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
The price is $66 per night
$66
per night
Oct 9 - Oct 10
Free Cancellation
Reserve now, pay when you stay
12.65 mi from Cairo Regional
Located in Charleston, Quality Inn Charleston I-57 is within a 15-minute drive of The Book Bug and City of Miner Convention Center.
Americas Best Value Inn Ullin Mounds

Americas Best Value Inn Ullin Mounds

2 out of 5
128 Cheekwood Lane, Ullin, IL
The price is $99 per night
$99
per night
Oct 8 - Oct 9
Free Cancellation
Reserve now, pay when you stay
14.91 mi from Cairo Regional
With a stay at Americas Best Value Inn Ullin Mounds in Ullin, you'll be 1.7 mi (2.8 km) from Ullin City Hall and 10.7 mi (17.2 km) from Henry N Barkhausen Cache River Wetlands Center.
Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.

Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.

15.45 mi from Cairo Regional
When you stay at this campground in Benton, you'll be 14 minutes by car from Front Street Studio & Art Gallery.
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
The price is $84 per night
$84
per night
Oct 1 - Oct 2
Free Cancellation
Reserve now, pay when you stay
20.6 mi from Cairo Regional
Located in Sikeston, Best Western Plus Sikeston is within a 15-minute walk of City of Miner Convention Center and The Book Bug.
Travel Inn & Suites

Travel Inn & Suites

2.5 out of 5
100 Matthews Lane, Sikeston, MO
The price is $58 per night
$58
per night
Oct 1 - Oct 2
Free Cancellation
Reserve now, pay when you stay
20.86 mi from Cairo Regional
Located in Sikeston, Travel Inn & Suites is in a rural location, within a 15-minute walk of The Book Bug and City of Miner Convention Center.
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is $68 per night
$68
per night
Oct 5 - Oct 6
Free Cancellation
Reserve now, pay when you stay
20.66 mi from Cairo Regional
With a stay at Days Inn and Suites by Wyndham Sikeston in Sikeston, you'll be within a 5-minute drive of The Book Bug and City of Miner Convention Center.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Sikeston, MO
The price is $99 per night
$99
per night
Oct 12 - Oct 13
Free Cancellation
Reserve now, pay when you stay
20.8 mi from Cairo Regional
A stay at Drury Inn & Suites Sikeston, MO places you in the heart of Sikeston, within a 5-minute walk of City of Miner Convention Center and The Book Bug.
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Cairo Regional hotels essential information

Accommodation
64 hotels
Lowest Price
$58
Highest Price
$110
Popular hotels
Quality Inn Cairo I-57, Super 8 by Wyndham Charleston MO, Cozy cabins on beautiful Horseshoe Lake, The Rested Duck Mallard Room, Eagle Inn Charleston, Quality Inn Charleston I-57, Americas Best Value Inn Ullin Mounds, Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024., Best Western Plus Sikeston, Travel Inn & Suites, Days Inn and Suites by Wyndham Sikeston, Drury Inn & Suites Sikeston, MO

Most Recent Cairo Regional Hotel Reviews

Travel Inn & Suites

Travel Inn & Suites

5 out of 5
Posted 3 days ago
CheapTickets Verified Review
"Very clean and nice for a budget hotel. Looks like it was very recently remodeled. "
A verified traveler stayed at Travel Inn & Suites
Travel Inn & Suites

Top 20 Cairo Regional Hotels

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