See all 2906 hotels in Upstate South Carolina
- Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG
- Woodspring Suites Anderson North I-85
- Horizon Inn & Suites
- Super 8 by Wyndham Greer/Spartanburg Area
- AC Hotel by Marriott Spartanburg
- stayAPT Suites Greenville Greer BMW
- Motel 6 Simpsonville, SC - Greenville
- Hampton Inn Anderson
- Fairfield By Marriott Inn & Suites Piedmont Greenville
- Tanglewood Inn
- Super 8 by Wyndham Gaffney
- Charming 4-bedroom farmhouse w/ WiFi, AC in lovely Eastatoee Valley, Sunset, SC.
- Pet-Friendly Room Near Falls Park on Reedy and Downtown Greenville Fun
- Econo Lodge
- Pet-Friendly Budget Room Close to Michelin HQ & Paris Mountain Park