See all 622 hotels in Southeast Missouri
- Drury Inn & Suites Cape Girardeau
- Pear Tree Inn Sikeston
- Baymont by Wyndham Festus
- Tru By Hilton Cape Girardeau
- Fairfield Inn & Suites by Marriott Sikeston
- Century Casino & Hotel Caruthersville
- Days Inn by Wyndham Perryville
- Hampton Inn By Hilton Dexter
- TownePlace Suites by Marriott Sikeston
- Triangle Inn Motel
- OYO Hickory House Inn
- OYO Malden Airport Inn
- Spring Lake Ranch has a Private, Rustic Lodge perfect for family/group retreats!
- Azaria Lodge - Sleeps up to 38 People - Keep Everyone Together as you Celebrate!
- Arcadia Academy
- YMCA Trout Lodge
- Relax with the whole family at Puckett’s View- Potosi, MO - Home Away From Home.
- Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!