See all 286 hotels in Sikeston
- Pear Tree Inn Sikeston
- Fairfield Inn & Suites by Marriott Sikeston
- TownePlace Suites by Marriott Sikeston
- Drury Inn & Suites Cape Girardeau
- Tru By Hilton Cape Girardeau
- Hampton Inn By Hilton Dexter
- Days Inn by Wyndham Perryville
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Charming farmhouse on a beautiful horse ranch-Shawnee Hills Wine Trail
- OYO Hickory House Inn
- Eagles Crossing is a Newly Renovated 3-Bed Farmhouse with a Large Deck & Hot Tub
- OYO Malden Airport Inn
- Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
- Beautiful Cabin Retreat
- Beautifully Renovated Farmhouse in Jackson, MO
- Charming 1-bedroom B&B with AC, WiFi in historic Cape Girardeau