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Cheap Cairo Hotels

Quality Inn Cairo I-57

13201 Kessler Road Cairo IL

$74 nightly

$83 total

Apr 29 - Apr 30

Total with taxes and fees

Free Cancellation

2.68 mi from city center

With a stay at Quality Inn Cairo I-57 in Cairo, you'll be within a 15-minute drive of Mississippi River and Ohio River Valley.

Breakfast included

Pet friendly

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

$65 nightly

$72 total

Apr 23 - Apr 24

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

10.04 mi from city center

With a stay at Super 8 by Wyndham Charleston/Sikeston East MO, you'll be centrally located in Charleston, 10.3 mi (16.6 km) from Mississippi River and 20.5 mi (33 km) from Shawnee National Forest.

Breakfast included

Pet friendly

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL

$159 nightly

$169 total

Apr 23 - Apr 24

Total with taxes and fees

10.85 mi from city center

This cabin is 0.3 mi (0.4 km) from Shawnee National Forest and 6.2 mi (9.9 km) from Ohio River Valley.

Kitchen

Pet friendly

The Riverstone Hotel Charleston-Sikeston

102 Drake St Charleston MO

$92 nightly

$102 total

Apr 23 - Apr 24

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

11.71 mi from city center

When you stay at The Riverstone Hotel Charleston-Sikeston in Charleston, you'll be 13 minutes by car from City of Miner Convention Center.

Breakfast included

Pet friendly

La Center Motel

474 W Kentucky Dr La Center KY

$65 nightly

$70 total

Apr 26 - Apr 27

Total with taxes and fees

11.79 mi from city center

When you stay at La Center Motel in La Center, you'll be 13 minutes by car from Ohio River Valley.

Parking included

Free WiFi

Cozy cabins on beautiful Horseshoe Lake

Olive Branch IL

$133 nightly

$140 total

Apr 23 - Apr 24

Total with taxes and fees

14.88 mi from city center

This cabin is 0.4 mi (0.7 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.

Air conditioning

Lake view

The Rested Duck Mallard Room

Olive Branch IL

$133 nightly

$140 total

Apr 26 - Apr 27

Total with taxes and fees

14.88 mi from city center

This cabin is 0.4 mi (0.7 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.

Air conditioning

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Kevil KY

17.75 mi from city center

With a stay at this vacation home in Kevil, you'll be 16.8 mi (27.1 km) from Mississippi River and 27 mi (43.4 km) from Shawnee National Forest.

Breakfast included

Kitchen

Eagle Inn Charleston

2811 East Marshall Street Charleston MO

$55 nightly

$61 total

May 2 - May 3

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

9.28 mi from city center

With a stay at Eagle Inn Charleston in Charleston, you'll be 10.1 mi (16.3 km) from Mississippi River and 20.6 mi (33.1 km) from Shawnee National Forest.

Pet friendly

Parking included

Charming cottage overlooking Lake Acre

Dongola IL

$261 nightly

$277 total

Apr 23 - Apr 24

Total with taxes and fees

24.79 mi from city center

Located in Dongola, this cabin is on a lake, within a 15-minute drive of Dongola Lake and Dongola Public Library.

Kitchen

Washer

Charming Home just minutes from Interstate and Mall

Kevil KY

$165 nightly

$187 total

May 4 - May 5

Total with taxes and fees

18.71 mi from city center

With a stay at this vacation home in Kevil, you'll be within a 15-minute drive of Ohio River Valley and Paul Rowton Indoor Tennis Center.

Kitchen

Washer

May graduates, hikers, bike riders, fisherman, side-by-siders--we got you!

Tamms IL

17.4 mi from city center

When you stay at this vacation home in Tamms, you'll be steps from Shawnee National Forest.

Kitchen

Washer

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cairo hotels essential information

Accommodation	28 hotels
Lowest Price	$61
Highest Price	$277
Popular hotels	Quality Inn Cairo I-57, Super 8 by Wyndham Charleston/Sikeston East MO, Peaceful secluded cabin located near Horseshoe Lake , The Riverstone Hotel Charleston-Sikeston, La Center Motel, Cozy cabins on beautiful Horseshoe Lake, The Rested Duck Mallard Room, Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286, Eagle Inn Charleston, Charming cottage overlooking Lake Acre, Charming Home just minutes from Interstate and Mall, May graduates, hikers, bike riders, fisherman, side-by-siders--we got you!